Developing experimental designs of pre-clinical drugs after stroke. In vivo model (middle cerebral artery occlusion), behavioral study (rotating pole), in vitro pharmacology study (myography), molecular biology techniques (microarray, immunohistochemistry, western blotting, qPCR, tunel staining).

Effect of risk factors (hypertensive rats) and gender differences (female and male rats) on vascular biology (cerebral arteries) and brain regions after experimental stroke.

Testing of different pre-clinical drugs in female rats after experimental stroke (subarachnoid hemorrhage). Following studies are applied: rotating pole, measurement of intracranial pressure, myography, tunel staining, edema measurement and immunohistochemistry.

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