Forskning
Udskriv Udskriv
Switch language
  1. Region Hovedstaden
  2. Forskere
  3. Anders Juul
Region Hovedstaden - en del af Københavns Universitetshospital
Anders Juul

Anders Juul

Blegdamsvej 9

Bygning: Rigshospitalet

2100 Copenhagen

Danmark

Blegdamsvej 9

Bygning: Rigshospitalet, Klinik for Vækst og Reproduktion

2100 København

Danmark

Telefon: 35455085Fax: 35456054
Download dette CV (PDF)
Profile photoAnders Juul
Professor, Head of Department
Department of Growth and Reproduction GR
Rigshospitalet 5064
Blegdamsvej 9
Copenhagen

Leader of EDMaRC
Rigshospitalet
Faculty of Health and Medical Sciences
University of Copenhagen
Denmark

Phone: +45 3545 5085
Email: anders.juul@regionh.dk
www.edmarc.net
www.reproduction.dk

Curriculum vitae

Education
1991Graduated in medicine, Universitety of Copenhagen
1995Ph.D. degree, University of Copenhagen
1996Authorisation as medical doctor (Danish Health Authorities)
2002Specialist in Paediatrics (Danish Health Authorities)
2003Doctoral dissertation (Dr.med.), University of Copenhagen
2005Expert in Medicical Andrology (certified Europ Academy Andrology)
2012Expert in Paediatric Endocrinology (certified Danish Paediatric Soc)

Current and most recent positions held
1991-94Research assistent/PhD student, Dept. of Growth and Reproduction, Rigshospitalet
1994-96Basic Clinical Training (urology, cardiology, general practitioner)
1996-97Paediatrc Training, Dept. Paediatrics, Glostrup University Hospital
1998-02Paediatric Training, Dept. of Paediatrics, Rigshospitalet
2002-04Consultant (afdelingslæge), Dept. of Growth and Reproduction, Rigshospitalet
2003-Clinical Research Assoc Professor, University of Copenhagen
2004-Consultant (overlæge), Dept. of Growth and Reproduction, Rigshospitalet
2006-Head of Department, Dept. of Growth and Reproduction, Rigshospitalet
2007-Full clinical Professor, Rigshospitalet & University of Copenhagen
2013-Coordinating Professor, JMC, Rigshospitalet and University of Copenhagen

Academic awards and honours
The European Society of Paediatric Endocrinology Research Award 2015

Clinical Expertise
In my outpatient clinic I manage children as well as adult males with rare endocrine disorders. I am considered an international expert in clinical management of patients with Klinefelter syndrome, pituitary and growth disorders, mixed gonadal dysgenesis and puberty disorders

Scientific qualifications
Research bibliometry:
H-index: 63 (Web of Science, Nov 1., 2018), 73 (Google Scholar, Sept 12, 2017)
Peer-reviewed publications: 350
Times cited: 13.334, 8 papers with impact factor >10 (Lancet, Physiol Rev, Nature Rev Endo, HRU, Circulation, Eur Urol) , 56 papers in J Clin Endocrinol Metab (IF 5.4), the leading endocrine journal

Scientific focus areas
Current research areas include:
1) Timing and regulation of normal puberty and its disorders 
2) Disorders of Sex Development (DSD); 47XXY, 45X, 45X/46XY, CAH, PAIS, CHH.
3) Effect of intrauterine growth retardation on postnatal growth, puberty and reproduction
4) Relation between IGF-I, reproductive hormones and adult lifestyle diseases,
5) Genetic and epigenetic modifications, pubertal timing, and gonadal function
6) Endocrine disrupting chemicals and endogenous hormones, pubertytiming and reproductive function in children and adults

Programme Organizing committees
−ESPE Symposium"Use and misuse of GH”, Firence, 1998
−ESPE consensus workshop ”The GHD adolescent in transition to adult care”, UK, 2003
−Pituitary course (Paediatric, Endocrine and Neurosurgical societies), Denmark 2004-
−European congress of endocrinology (ECE), Berlin 2008
−16th world Congress of Pediatric and Adolescent Gynecology, Montpellier 2010
−1st International Workshop on Klinefelter syndrome, Copenhagen May 2010
−Copenhagen Workshop on Endocrine Disruptors. May 2013
−Endocrine Society Annual Meeting Steering Committee (2018-2020)
−Dronning Louises Børnehospitals Grant committee (2001-2010)
−Anti Doping Danmarks udvalg for forskning og medicin (2004-)
−Rigshospitalets Research council (2007-2013)
−ESPE Research Fellowship Grant Committee (secretary) (1999-2012)

Administrative experience
−Scientific consultant for Diagnostic Systems Laboratories, Inc, USA. 1995-1997
−ESPE Drugs and Therapeutics Committee (DTC) (1999-2005)
−Scientific Secretary Endocrinology committee Danish Paediatric Society (1998-2002)
−Chairman Endocrinology committee Danish Paediatric Society (2002-2004)
−Medical Expert in Medical committee (TUE), Anti Doping Danmark (2004-14)
−Director University Research Cluster for ”Fetal Environment and Postnatal Disease” University of Copenhagen (2005-10)
−Coordinator on Danish Network for Endocrine Disruption (DAN-ED) (DSF grant 2005-9)
−Head of Department (2006 - ), Dept Growth and Reproduction, Rigshospitalet
−Steering committee ”Reprosund” 2009-2012, and ”ReproHigh” 2012-2015
−Participant HS leadership programme (2005-6; team 10)
−Participant RegionH leadership programme “ledelse af ledere”, 2012 (12.5 days)
−Chairman, Internationaliseringspuljen, Institute of Clinical Medicine (2016 -)
−Steeting committee, Rigshospitalets assoc for professors (professorsammenslutningen)
−Steering committee, and Co-chairman European Reference Network ENDO ERN, Work
package on laboratory diagnostics and genetics (may 2016- ) web: https://endo-ern.eu/
−Rigshospitalets Research Strategic Council (forskningsstrategisk råd) (2017- )

International research relations
Principal investigator on NorthEuropean Multicenter clinical trial on GH treatment of short SGA children (NESGAS). National representative in EU COST consortia (DSD and GnRH deficiency), part of numerous international research collaborations with top international scientists from Harvard (professor Lanske), Turku (professor Toppari), Glasgow (professor Ahmed) and Cambridge Universities (professor Dunger, MRC programme leaders Ong and Perry)

Supervision of students
Supervisor of 29 Ph.D. students, herof 11 ongoing, and 18 succesfully completed and numerous master students. Reviewer on 22 PhD theses and 6 doctoral theses.

Dissertations (PhD and Doctoral Dissertation)
Juul, A. (2003). Serum levels of insulin-like growth factor I and its binding proteins in health and disease. København: Eget forlag.
Juul, A. (1995). Serum levels of IGF-I and IGFBP-3 in healthy children, adolescents and adults; Methodological aspects and definition of reference values with special emphasis on puberty. København: Eget forlag.

Publications (peer reviewed)

Juul, A., & Skakkebæk, N. E. (2019). Why do normal children have acromegalic levels of IGF-I during puberty? The Journal of clinical endocrinology and metabolism. https://doi.org/10.1210/jc.2018-02099
Rehfeld, A., Egeberg Palme, D. L., Almstrup, K., Juul, A., & Skakkebaek, N. E. (2019). Medium-throughput Screening Assays for Assessment of Effects on Ca2+-Signaling and Acrosome Reaction in Human Sperm. Journal of visualized experiments : JoVE, (145). https://doi.org/10.3791/59212
Jensen, T. K., Mustieles, V., Bleses, D., Frederiksen, H., Trecca, F., Schoeters, G., ... Andersson, A-M. (2019). Prenatal bisphenol A exposure is associated with language development but not with ADHD-related behavior in toddlers from the Odense Child Cohort. Environmental Research, 170, 398-405. https://doi.org/10.1016/j.envres.2018.12.055
Sadov, S., Virtanen, H. E., Main, K. M., Andersson, A-M., Juul, A., Jula, A., ... Toppari, J. (2019). Low-saturated-fat and low-cholesterol diet does not alter pubertal development and hormonal status in adolescents. Acta paediatrica, 108(2), 321-327. https://doi.org/10.1111/apa.14480
Assens, M., Frederiksen, H., Petersen, J. H., Larsen, T., Skakkebæk, N. E., Juul, A., ... Main, K. M. (2019). Variations in repeated serum concentrations of UV filters, phthalates, phenols and parabens during pregnancy. Environment International, 123, 318-324. https://doi.org/10.1016/j.envint.2018.11.047
Damsgaard, D., & Juul, A. (2019). Miljøet skader dansk sæd og vækst. Ugeskrift for læger [online].
Priskorn, L., Bang, A. K., Nordkap, L., Krause, M., Mendiola, J., Jensen, T. K., ... Jørgensen, N. (2019). Anogenital distance is associated with semen quality but not reproductive hormones in 1106 young men from the general population. Human reproduction (Oxford, England). https://doi.org/10.1093/humrep/dey326
Melau, C., Nielsen, J. E., Frederiksen, H., Kilcoyne, K., Perlman, S., Lundvall, L., ... Jørgensen, A. (2019). Characterization of Human Adrenal Steroidogenesis during Fetal Development. The Journal of clinical endocrinology and metabolism, epub. https://doi.org/10.1210/jc.2018-01759
Jørgensen, A., Macdonald, J., Nielsen, J. E., Kilcoyne, K. R., Perlman, S., Lundvall, L., ... Mitchell, R. T. (2018). Nodal Signaling Regulates Germ Cell Development and Establishment of Seminiferous Cords in the Human Fetal Testis. Cell Reports, 25(7), 1924-1937.e4. https://doi.org/10.1016/j.celrep.2018.10.064
Olesen, I. A., Joensen, U. N., Petersen, J. H., Almstrup, K., Rajpert-De Meyts, E., Carlsen, E., ... Jørgensen, N. (2018). Decrease in semen quality and Leydig cell function in infertile men: a longitudinal study. Human reproduction (Oxford, England), 33(11), 1963-1974. https://doi.org/10.1093/humrep/dey283
Jørgensen, J. O., Hermansen, K., Stochholm, K., & Juul, A. (2018). Adult Growth Hormone Deficiency: from Transition to Senescence. Pediatric Endocrinology Reviews, 16(Suppl 1), 70-79. https://doi.org/10.17458/per.vol16.2018.jhs.adultghdeficiency
Blomberg Jensen, M., Husted, H., Bjerrum, P. J., Juul, A., & Kehlet, H. (2018). Compromised Activation of Vitamin D After Elective Surgery: A Prospective Pilot Study. JBMR Plus, 2(5), 281-288. https://doi.org/10.1002/jbm4.10053
Ridefelt, P., Hilsted, L., Juul, A., Hellberg, D., & Rustad, P. (2018). Pediatric reference intervals for general clinical chemistry components - merging of studies from Denmark and Sweden. Scandinavian Journal of Clinical and Laboratory Investigation, 78(5), 365-372. https://doi.org/10.1080/00365513.2018.1474493
Tarsitano, M. G., Bandak, M., Jørgensen, N., Skakkebaek, N. E., Juul, A., Lenzi, A., ... Rajpert-De Meyts, E. (2018). Quantification of the Leydig cell compartment in testicular biopsies and association with biochemical Leydig cell dysfunction in testicular cancer survivors. Andrology, 6(5), 748-755. https://doi.org/10.1111/andr.12508
Öberg, D., Salemyr, J., Örtqvist, E., Juul, A., & Bang, P. (2018). A longitudinal study of serum insulin-like growth factor-I levels over 6 years in a large cohort of children and adolescents with type 1 diabetes mellitus: A marker reflecting diabetic retinopathy. Pediatric Diabetes, 19(5), 972-978. https://doi.org/10.1111/pedi.12681
Winge, S. B., Dalgaard, M. D., Belling, K. G., Jensen, J. M., Nielsen, J. E., Aksglaede, L., ... Almstrup, K. (2018). Transcriptome analysis of the adult human Klinefelter testis and cellularity-matched controls reveals disturbed differentiation of Sertoli- and Leydig cells. Cell Death and Differentiation, 9(6), 586. https://doi.org/10.1038/s41419-018-0671-1
Andreassen, M., Juul, A., Feldt-Rasmussen, U., & Jørgensen, N. (2018). Semen quality in patients with pituitary disease and adult-onset hypogonadotropic hypogonadism. Endocrine Connections, 7(4), 523-533. https://doi.org/10.1530/EC-18-0061
Krause, M., Frederiksen, H., Sundberg, K., Jørgensen, F. S., Jensen, L. N., Nørgaard, P., ... Andersson, A-M. (2018). Maternal exposure to UV filters and associations to maternal thyroid hormones and IGF-I/IGFBP3 and birth outcomes. Endocrine Connections, 7(2), 334-346. https://doi.org/10.1530/EC-17-0375
Jensen, R. B., Thankamony, A., Holst, K. K., Janssen, J. A. M. J. L., Juul, A., Dunger, D., ... Scheike, T. (2018). Genetic influence on the associations between IGF-I and glucose metabolism in a cohort of elderly twins. European Journal of Endocrinology, 178(2), 155-163. https://doi.org/10.1530/EJE-17-0754
Greiber, I. K., Hagen, C. P., Busch, A. S., Mieritz, M. G., Aksglæde, L., Main, K., ... Juul, A. (2018). The AMH genotype (rs10407022 T>G) is associated with circulating AMH levels in boys, but not in girls. Endocrine Connections, 7(2), 347-354. https://doi.org/10.1530/EC-17-0299
Busch, A. S., Hagen, C. P., Assens, M., Main, K. M., Almstrup, K., & Juul, A. (2018). Differential Impact of Genetic Loci on Age at Thelarche and Menarche in Healthy Girls. The Journal of clinical endocrinology and metabolism, 103(1), 228-234. https://doi.org/10.1210/jc.2017-01860
Carlsson, A., Sørensen, K., Andersson, A-M., Frederiksen, H., & Juul, A. (2018). Bisphenol A, phthalate metabolites and glucose homeostasis in healthy normal-weight children. Endocrine Connections, 7(1), 232-238. https://doi.org/10.1530/EC-17-0344
Krause, M., Frederiksen, H., Sundberg, K., Jørgensen, F. S., Jensen, L. N., Nørgaard, P., ... Andersson, A. M. (2018). Presence of benzophenones commonly used as UV filters and absorbers in paired maternal and fetal samples. Environmental International, 110, 51-60. https://doi.org/10.1016/j.envint.2017.10.005
Priskorn, L., Nordkap, L., Bang, A. K., Krause, M., Holmboe, S. A., Egeberg Palme, D. L., ... Jørgensen, N. (2018). Average sperm count remains unchanged despite reduction in maternal smoking: results from a large cross-sectional study with annual investigations over 21 years. Human reproduction (Oxford, England), 33(6), 998-1008. https://doi.org/10.1093/humrep/dey090
Mouritsen, A. K., Busch, A. S., Aksglaede, L., Rajpert-De Meyts, E., & Juul, A. (2018). Deletion in the uridine diphosphate glucuronyltransferase 2B17 gene is associated with delayed pubarche in healthy boys. Endocrine Connections, 7(3), 460-465. https://doi.org/10.1530/EC-18-0080
Albrethsen, J., Frederiksen, H., Andersson, A-M., Anand-Ivell, R., Nordkap, L., Bang, A. K., ... Juul, A. (2018). Development and validation of a mass spectrometry-based assay for quantification of insulin-like factor 3 in human serum. Clinical Chemistry and Laboratory Medicine, 56(11), 1913-20. https://doi.org/10.1515/cclm-2018-0171
Abildgaard, J., Danielsen, E. R., Dorph, E., Thomsen, C., Juul, A., Ewertsen, C., ... Lindegaard, B. (2018). Ectopic lipid deposition is associated with insulin resistance in postmenopausal women. The Journal of clinical endocrinology and metabolism, 103(9), 3394-3404. https://doi.org/10.1210/jc.2018-00554
Blomberg Jensen, M., Lawaetz, J. G., Petersen, J. H., Juul, A., & Jørgensen, N. (2018). Effects of vitamin D supplementation on semen quality, reproductive hormones and live birth rate: a randomized clinical trial. The Journal of clinical endocrinology and metabolism, 103(3), 870-881. https://doi.org/10.1210/jc.2017-01656
Johannsson, G., Bidlingmaier, M., Biller, B., Boguszewski, M., Casanueva, F. F., Chanson, P., ... Jørgensen, J. O. L. (2018). Growth Hormone Research Society perspective on biomarkers of GH action in children and adults. Endocrine Connections, 7(3), R126-R134. https://doi.org/10.1530/EC-18-0047
Kristensen, D. M., Desdoits-Lethimonier, C., Mackey, A. L., Dalgaard, M. D., De Masi, F., Munkbøl, C. H., ... Jégou, B. (2018). Ibuprofen alters human testicular physiology to produce a state of compensated hypogonadism. Proceedings of the National Academy of Sciences of the United States of America, 115(4), E715-E724. https://doi.org/10.1073/pnas.1715035115
Holmboe, S. A., Skakkebaek, N. E., Juul, A., Scheike, T., Jensen, T. K., Linneberg, A., ... Andersson, A-M. (2018). Individual testosterone decline and future mortality risk in men. European Journal of Endocrinology, 178(1), 123-130. https://doi.org/10.1530/EJE-17-0280
Bang, A. K., Busch, A. S., Almstrup, K., Gromoll, J., Kliesch, S., Rajpert-De Meyts, E., ... Jørgensen, N. (2018). Is the FSHR 2039A>G variant associated with susceptibility to testicular germ cell cancer? Andrology, 6(1), 176-83. https://doi.org/10.1111/andr.12440
Bandak, M., Jørgensen, N., Juul, A., Lauritsen, J., Kier, M. G. G., Mortensen, M. S., & Daugaard, G. (2018). Longitudinal Changes in Serum Levels of Testosterone and Luteinizing Hormone in Testicular Cancer Patients after Orchiectomy Alone or Bleomycin, Etoposide, and Cisplatin. European Urology Focus, 4(4), 591-598. https://doi.org/10.1016/j.euf.2016.11.018
Koskenniemi, J. J., Virtanen, H. E., Wohlfahrt-Veje, C., Löyttyniemi, E., Skakkebaek, N. E., Juul, A., ... Toppari, J. (2018). Postnatal Changes in Testicular Position are Associated with IGF-I and Function of Sertoli and Leydig Cells. The Journal of clinical endocrinology and metabolism, 103(4), 1429-1437. https://doi.org/10.1210/jc.2017-01889
Aksglaede, L., Olesen, I. A., Carlsen, E., Petersen, J. H., Juul, A., & Jørgensen, N. (2018). Serum concentration of anti-Müllerian hormone is not associated with semen quality. Andrology, 6(2), 286-92. https://doi.org/10.1111/andr.12456
Fisher, B. G., Frederiksen, H., Andersson, A-M., Juul, A., Thankamony, A., Ong, K. K., ... Acerini, C. L. (2018). Serum Phthalate and Triclosan Levels Have Opposing Associations With Risk Factors for Gestational Diabetes Mellitus. Frontiers in Endocrinology, 9, 99. https://doi.org/10.3389/fendo.2018.00099
Johannsen, T. H., Main, K. M., Ljubicic, ML., Jensen, T. K., Andersen, H. R., Andersen, M. S., ... Juul, A. (2018). Sex-Differences in Reproductive Hormones during Mini-Puberty in Infants with Normal and Disordered Sex Development. The Journal of clinical endocrinology and metabolism, 103(8), 3028-3037. https://doi.org/10.1210/jc.2018-00482
Winge, S. B., Dalgaard, M. D., Jensen, J. M., Graem, N., Schierup, M. H., Juul, A., ... Almstrup, K. (2018). Transcriptome profiling of fetal Klinefelter testis tissue reveals a possible involvement of long non-coding RNAs in gonocyte maturation. Human Molecular Genetics, 27(3), 430-39. https://doi.org/10.1093/hmg/ddx411
Egeberg Palme, D. L., Rehfeld, A., Bang, A. K., Nikolova, K. A., Kjærulff, S., Petersen, M. R., ... Almstrup, K. (2018). Viable acrosome-intact human spermatozoa in the ejaculate as a marker of semen quality and fertility status. Human reproduction (Oxford, England), 33(3), 361-371. https://doi.org/10.1093/humrep/dex380
Mørup, N., Busch, A. S., Bang, A. K., Nordkap, L., Nielsen, J. E., Rajpert-De Meyts, E., ... Almstrup, K. (2017). Polymorphisms in JMJD1C are associated with pubertal onset in boys and reproductive function in men. Scientific Reports, 7(1), 17242. https://doi.org/10.1038/s41598-017-17575-9
Juel Mortensen, L., Blomberg Jensen, M., Christiansen, P., Rønholt, A-M., Jørgensen, A., Frederiksen, H., ... Juul, A. (2017). Germ Cell Neoplasia in Situ and Preserved Fertility Despite Suppressed Gonadotropins in a Patient With Testotoxicosis. The Journal of clinical endocrinology and metabolism, 102(12), 4411-4416. https://doi.org/10.1210/jc.2017-01761
Nordkap, L., Almstrup, K., Nielsen, J. E., Bang, A. K., Priskorn, L., Krause, M., ... Jørgensen, N. (2017). Possible involvement of the glucocorticoid receptor (NR3C1) and selected NR3C1 gene variants in regulation of human testicular function. Andrology, 5(6), 1105-1114. https://doi.org/10.1111/andr.12418
Kolby, N., Busch, A. S., Aksglaede, L., Sørensen, K., Petersen, J. H., Andersson, A-M., & Juul, A. (2017). Nocturnal Urinary Excretion of FSH and LH in Children and Adolescents With Normal and Early Puberty. The Journal of clinical endocrinology and metabolism, 102(10), 3830-3838. https://doi.org/10.1210/jc.2017-01192
Bandak, M., Jørgensen, N., Juul, A., Lauritsen, J., Oturai, P. S., Mortensen, J., ... Daugaard, G. (2017). Leydig cell dysfunction, systemic inflammation and metabolic syndrome in long-term testicular cancer survivors. European journal of cancer (Oxford, England : 1990), 84, 9-17. https://doi.org/10.1016/j.ejca.2017.07.006
Boisen, I. M., Bøllehuus Hansen, L., Mortensen, L. J., Lanske, B., Juul, A., & Blomberg Jensen, M. (2017). Possible influence of vitamin D on male reproduction. The Journal of steroid biochemistry and molecular biology, 173, 215-222. https://doi.org/10.1016/j.jsbmb.2016.09.023
Lorenzen, M., Boisen, I. M., Mortensen, L. J., Lanske, B., Juul, A., & Jensen, M. B. (2017). Reproductive endocrinology of vitamin D. Molecular and Cellular Endocrinology, 453, 103-112. https://doi.org/10.1016/j.mce.2017.03.023
Bandak, M., Jørgensen, N., Juul, A., Lauritsen, J., Kreiberg, M., Oturai, P. S., ... Daugaard, G. (2017). A randomized double-blind study of testosterone replacement therapy or placebo in testicular cancer survivors with mild Leydig cell insufficiency (Einstein-intervention). B M C Cancer, 17(1), e461. https://doi.org/10.1186/s12885-017-3456-5
Tinggaard, J., Hagen, C. P., Christensen, A. N., Mouritsen, A., Mieritz, M. G., Wohlfahrt-Veje, C., ... Main, K. M. (2017). Anthropometry, DXA, and leptin reflect subcutaneous but not visceral abdominal adipose tissue on MRI in 197 healthy adolescents. Pediatric Research, 82, 620–628. https://doi.org/10.1038/pr.2017.138
Bandak, M., Jørgensen, N., Juul, A., Lauritsen, J., Kier, M. G. G., Mortensen, M. S., ... Daugaard, G. (2017). Reproductive hormones and metabolic syndrome in 24 testicular cancer survivors and their biological brothers. Andrology, 5(4), 718-724. https://doi.org/10.1111/andr.12355
Weischendorff, S., Kielsen, K., Sengeløv, H., Jordan, K., Nielsen, C. H., Pedersen, A. E., ... Müller, K. G. (2017). Associations between levels of insulin-like growth factor 1 and sinusoidal obstruction syndrome after allogeneic haematopoietic stem cell transplantation. Bone Marrow Transplantation, 52(6), 863-869. https://doi.org/10.1038/bmt.2017.43
Holmboe, S. A., Priskorn, L., Jørgensen, N., Skakkebaek, N. E., Linneberg, A., Juul, A., & Andersson, A-M. (2017). Influence of marital status on testosterone levels-A ten year follow-up of 1113 men. Psychoneuroendocrinology, 80, 155-161. https://doi.org/10.1016/j.psyneuen.2017.03.010
Vestergaard, E. T., Schjørring, M. E., Kamperis, K., Petersen, K. K., Rittig, S., Juul, A., ... Birkebaek, N. H. (2017). The follicle-stimulating hormone (FSH) and luteinizing hormone (LH) response to a gonadotropin-releasing hormone analogue test in healthy prepubertal girls aged 10 months to 6 years. European Journal of Endocrinology, 176(6), 747-753. https://doi.org/10.1530/EJE-17-0042
Lottrup, G., Belling, K., Leffers, H., Nielsen, J. E., Dalgaard, M. D., Juul, A., ... Rajpert-De Meyts, E. (2017). Comparison of global gene expression profiles of microdissected human foetal Leydig cells with their normal and hyperplastic adult equivalents. Molecular Human Reproduction, 23(5), 339-354. https://doi.org/10.1093/molehr/gax012
Busch, A. S., Hagen, C. P., Main, K. M., Pereira, A., Corvalan, C., Almstrup, K., ... Juul, A. (2017). Genetic Variation of Follicle-Stimulating Hormone Action Is Associated With Age at Testicular Growth in Boys. The Journal of clinical endocrinology and metabolism, 102(5), 1740-1749. https://doi.org/10.1210/jc.2016-4013
Egeberg Palme, D. L., Johannsen, T. H., Petersen, J. H., Skakkebæk, N. E., Juul, A., Jørgensen, N., & Almstrup, K. (2017). Validation of image cytometry for sperm concentration measurement: Comparison with manual counting of 4010 human semen samples. Clinica chimica acta; international journal of clinical chemistry, 468, 114-119. https://doi.org/10.1016/j.cca.2017.02.014
Kirk, I. K., Weinhold, N., Belling, K. C., Skakkebæk, N. E., Jensen, T. S., Leffers, H., ... Brunak, S. (2017). Chromosome-wise Protein Interaction Patterns and Their Impact on Functional Implications of Large-Scale Genomic Aberrations. Cell Systems, 4(3), 357-364.e3. https://doi.org/10.1016/j.cels.2017.01.001
Badiu, C., Bonomi, M., Borshchevsky, I., Cools, M., Craen, M., Ghervan, C., ... COST Action BM1105 (2017). Developing and evaluating rare disease educational materials co-created by expert clinicians and patients: the paradigm of congenital hypogonadotropic hypogonadism. Orphanet Journal of Rare Diseases, 12(1), 57. https://doi.org/10.1186/s13023-017-0608-2
Holst, J. M., Horváth-Puhó, E., Jensen, R., Rix, M., Hertel, N. T., Dekkers, O., ... Jorgensen, J. O. L. (2017). Cushing's Syndrome in Children and Adolescents: A Danish Nationwide Population-Based Cohort Study. European Journal of Endocrinology, 176, 567-74. https://doi.org/10.1530/EJE-16-0843
Mieritz, M. G., Christiansen, P., Jensen, M. B., Joensen, U. N., Nordkap, L., Olesen, I. A., ... Joergensen, N. (2017). Gynaecomastia in 786 Adult Men - Clinical and Biochemical findings. European Journal of Endocrinology, 176, 555-66. https://doi.org/10.1530/EJE-16-0643
Bang, A. K., Nordkap, L., Almstrup, K., Priskorn, L., Petersen, J. H., Rajpert-De Meyts, E., ... Joergensen, N. (2017). Dynamic GnRH- and hCG-testing: establishment of new diagnostic reference levels. European Journal of Endocrinology, 176(4), 379-391. https://doi.org/10.1530/EJE-16-0912
Olesen, I. A., Andersson, A-M., Aksglaede, L., Skakkebaek, N. E., Rajpert-de Meyts, E., Joergensen, N., & Juul, A. (2017). Clinical, genetic, biochemical, and testicular biopsy findings among 1,213 men evaluated for infertility. Fertility and Sterility, 107(1), 74-82. https://doi.org/10.1016/j.fertnstert.2016.09.015
Kranenburg, L. J. C., Reerds, S. T. H., Cools, M., Alderson, J., Muscarella, M., Magrite, E., ... Drop, S. L. S. (2017). Global Application of the Assessment of Communication Skills of Paediatric Endocrinology Fellows in the Management of Differences in Sex Development Using the ESPE E-Learning.Org Portal. Hormone research in paediatrics, 88, 127-39. https://doi.org/10.1159/000475992
Bliddal, S., Boas, M., Hilsted, L., Friis-Hansen, L., Juul, A., Larsen, T., ... Feldt-Rasmussen, U. (2017). Increase in thyroglobulin antibody and thyroid peroxidase antibody levels, but not preterm birth-rate, in pregnant Danish women upon iodine fortification. European Journal of Endocrinology, 176(5), 603-612. https://doi.org/10.1530/EJE-16-0987
Søeborg, T., Frederiksen, H., Johannsen, T. H., Andersson, A-M., & Juul, A. (2017). Isotope-dilution TurboFlow-LC-MS/MS method for simultaneous quantification of ten steroid metabolites in serum. Clinica chimica acta; international journal of clinical chemistry, 468, 180-186. https://doi.org/10.1016/j.cca.2017.03.002
Belling, K., Russo, F., Jensen, A. B., Dalgaard, M. D., Westergaard, D., Rajpert-De Meyts, E., ... Brunak, S. (2017). Klinefelter Syndrome Comorbidities Linked to Increased X Chromosome Gene Dosage and Altered Protein Interactome Activity. Human Molecular Genetics, 26(7), 1219-1229. [doi: 10.1093/hmg/ddx014].
Mogensen, D. M., Pihl, M. B., Skakkebæk, N. E., Andersen, H. R., Juul, A., Kyhl, H. B., ... Jensen, T. K. (2017). Prenatal exposure to antifungal medication may change anogenital distance in male offspring: a preliminary study. Environmental Health: A Global Access Science Source, 16(1), 68. https://doi.org/10.1186/s12940-017-0263-z
Bandak, M., Jørgensen, N., Juul, A., Lauritsen, J., Kier, M. G. G., Mortensen, M. S., & Daugaard, G. (2017). Preorchiectomy Leydig Cell Dysfunction in Patients With Testicular Cancer. Clinical Genitourinary Cancer (Online), 15(1), e37-e43. https://doi.org/10.1016/j.clgc.2016.07.006
Marstrand-Joergensen, M. R., Beck Jensen, R., Aksglaede, L., Dunoe, M., & Juul, A. (2017). Prevalence of SHOX Haploinsufficiency among Short Statured Children. Pediatric Research, 81(2), 335-341. https://doi.org/10.1038/pr.2016.233
Johansen, M. L., Hagen, C. P., Mieritz, M. G., Wolthers, O. D., Heuck, C., Petersen, J. H., & Juul, A. (2017). Pubertal Progression and Reproductive Hormones in Healthy Girls with Transient Thelarche. The Journal of clinical endocrinology and metabolism, 102(3), 1001-1008. https://doi.org/10.1210/jc.2016-2871
Bøllehuus Hansen, L., Rehfeld, A., de Neergaard, R., Nielsen, J. E., Iversen, L. H., Boisen, I. M., ... Blomberg Jensen, M. (2017). Selection of high quality spermatozoa may be promoted by activated vitamin D in the woman. The Journal of clinical endocrinology and metabolism, 102(3), 950-61. https://doi.org/10.1210/jc.2016-3008
Upners, E. N., Jensen, R. B., Rajpert-De Meyts, E., Dunø, M., Aksglaede, L., & Juul, A. (2017). Short stature homeobox-containing gene duplications in 3.7% of girls with tall stature and normal karyotypes. Acta paediatrica, 106(10), 1651-57. https://doi.org/10.1111/apa.13969
Wegmann , M. G., Thankamony, A., Roche, E., Hoey, H., Kirk, J., Shaikh, G., ... Jensen, R. B. (2017). The exon3-deleted Growth Hormone Receptor Gene polymorphism (d3-GHR) is associated with insulin metabolism and spontaneous growth in short SGA children (NESGAS). Growth Hormone & IGF Research, 35, 45-51.
Dessens A, A., Filho, GG., Kyriakou , A., Bryce, J., Sanders, C., Nordenskjöld, A., ... Ahmed, SF. (2017). Understanding the needs of professionals who provide psychosocial care for children and adults with a disorder in sex development. BMJ Paediatrics Open , e000132.
Dessens, A., Guaragna-Filho, G., Kyriakou, A., Bryce, J., Sanders, C., Nordenskjöld, A., ... Faisal Ahmed, S. (2017). Understanding the needs of professionals who provide psychosocial care for children and adults with disorders of sex development. BMJ Paediatrics Open , 1(1), e000132. https://doi.org/10.1136/bmjpo-2017-000132
Frederiksen, H., Nielsen, O., Skakkebaek, N. E., Juul, A., & Andersson, A-M. (2017). UV filters analyzed by isotope diluted TurboFlow-LC-MS/MS in urine from Danish children and adolescents. International Journal of Hygiene and Environmental Health, 220(2), 244-53. https://doi.org/10.1016/j.ijheh.2016.08.005
Kyriakou, A., Dessens, A., Bryce, J., Iotova, V., Juul, A., Krawczynski, M., ... Ahmed, S. F. (2016). Current models of care for disorders of sex development - results from an International survey of specialist centres. Orphanet Journal of Rare Diseases, 11(1), 155. https://doi.org/10.1186/s13023-016-0534-8
Thankamony, A., Jensen, R. B., O'Connell, S. M., Day, F., Kirk, J., Donaldson, M., ... Juul, A. (2016). Adiposity in children born small for gestational age is associated with β-cell function, genetic variants for insulin resistance and response to growth hormone treatment. The Journal of clinical endocrinology and metabolism, 101(1), 131-42. https://doi.org/10.1210/jc.2015-3019
Upners, E. N., & Juul, A. (2016). Evaluation and phenotypic characteristics of 293 Danish girls with tall stature: effects of oral administration of natural 17β-estradiol. Pediatric Research, 80(5), 693-701. https://doi.org/10.1038/pr.2016.128
Lucas-Herald, A., Bertelloni, S., Juul, A., Bryce, J., Jiang, J., Rodie, M., ... Ahmed, S. F. (2016). The Long-Term Outcome of Boys With Partial Androgen Insensitivity Syndrome and a Mutation in the Androgen Receptor Gene. The Journal of clinical endocrinology and metabolism, 101(11), 3959-3967. https://doi.org/10.1210/jc.2016-1372
Teumer, A., Qi, Q., Nethander, M., Aschard, H., Bandinelli, S., Beekman, M., ... CHARGE Longevity Working Group (2016). Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits. Aging Cell, 15(5), 811-24. https://doi.org/10.1111/acel.12490
Rasmussen, J. J., Selmer, C., Østergren, P. B., Pedersen, K. B., Schou, M., Gustafsson, F., ... Kistorp, C. (2016). Former Abusers of Anabolic Androgenic Steroids Exhibit Decreased Testosterone Levels and Hypogonadal Symptoms Years after Cessation: A Case-Control Study. P L o S One, 11(8), e0161208. https://doi.org/10.1371/journal.pone.0161208
Holmboe, S. A., Jensen, T. K., Linneberg, A., Scheike, T., Thuesen, B. H., Skakkebaek, N. E., ... Andersson, A-M. (2016). Low Testosterone: A Risk Marker Rather Than a Risk Factor for Type 2 Diabetes. The Journal of clinical endocrinology and metabolism, 101(8), 3180-90. https://doi.org/10.1210/jc.2016-1778
Jensen, T. K., Finne, K. F., Skakkebæk, N. E., Andersson, A-M., Olesen, I. A., Joensen, U. N., ... Juul, A. (2016). Self-reported onset of puberty and subsequent semen quality and reproductive hormones in healthy young men. Human reproduction (Oxford, England), 31(8), 1886-94. https://doi.org/10.1093/humrep/dew122
Blomberg Jensen, M., Gerner Lawaetz, J., Andersson, A-M., Petersen, J. H., Nordkap, L., Bang, A. K., ... Jørgensen, N. (2016). Vitamin D deficiency and low ionized calcium are linked with semen quality and sex steroid levels in infertile men. Human reproduction (Oxford, England), 31(8), 1875-85. https://doi.org/10.1093/humrep/dew152
Damsgaard, J., Joensen, U. N., Carlsen, E., Erenpreiss, J., Blomberg Jensen, M., Matulevicius, V., ... Jørgensen, N. (2016). Varicocele Is Associated with Impaired Semen Quality and Reproductive Hormone Levels: A Study of 7035 Healthy Young Men from Six European Countries. European Urology, 70(6), 1019-1029. https://doi.org/10.1016/j.eururo.2016.06.044
Fugl, L., Hagen, C. P., Mieritz, M. G., Tinggaard, J., Fallentin, E., Main, K. M., & Juul, A. (2016). Glandular breast tissue volume by magnetic resonance imaging in 100 healthy peripubertal girls: evaluation of clinical Tanner staging. Pediatric Research, 80(4), 526-30. https://doi.org/10.1038/pr.2016.125
Almstrup, K., Lindhardt Johansen, M., Busch, A. S., Hagen, C. P., Nielsen, J. E., Petersen, J. H., & Juul, A. (2016). Pubertal development in healthy children is mirrored by DNA methylation patterns in peripheral blood. Scientific Reports, 6, 28657. https://doi.org/10.1038/srep28657
Bandak, M., Jørgensen, N., Juul, A., Vogelius, I. R., Lauritsen, J., Kier, M. G. G., ... Daugaard, G. (2016). Testosterone deficiency in testicular cancer survivors - a systematic review and meta-analysis. Andrology, 4(3), 382-8. https://doi.org/10.1111/andr.12177
Busch, A. S., Hagen, C. P., Almstrup, K., & Juul, A. (2016). Circulating MKRN3 levels decline during puberty in healthy boys. The Journal of clinical endocrinology and metabolism, jc20161488. https://doi.org/10.1210/jc.2016-1488
Busch, A. S., Hagen, C. P., Almstrup, K., Main, K. M., & Juul, A. (2016). Genetic variations altering FSH action affect circulating hormone levels as well as follicle growth in healthy peripubertal girls. Human reproduction (Oxford, England), 31(4), 897-904. https://doi.org/10.1093/humrep/dew022
Christiansen, J. S., Backeljauw, P., Bidlingmaier, M., Biller, B., Boguszewski, M., Casanueva, F. F., ... Yuen, K. C. (2016). Growth Hormone Research Society Perspective on the Development of Long-Acting Growth Hormone Preparations. European journal of endocrinology / European Federation of Endocrine Societies, 174(6), C1-8. https://doi.org/10.1530/EJE-16-0111
Damgaard-Olesen, A., Johannsen, T. H., Holmboe, S. A., Søeborg, T., Petersen, J. H., Andersson, A., ... Juul, A. (2016). Reference ranges of 17-hydroxyprogesterone, DHEA, DHEAS, androstenedione, total and free testosterone determined by TurboFlow-LC-MS/MS and associations to health markers in 304 men. Clinica chimica acta; international journal of clinical chemistry, 454, 82-8. https://doi.org/10.1016/j.cca.2015.12.042
Varimo, T., Hero, M., Laitinen, E-M., Miettinen, P. J., Tommiska, J., Känsäkoski, J., ... Raivio, T. (2016). Childhood growth in boys with congenital hypogonadotropic hypogonadism. Pediatric Research, 79(5), 705-9. https://doi.org/10.1038/pr.2015.278
Bourguignon, J-P., Juul, A., Franssen, D., Fudvoye, J., Pinson, A., & Parent, A-S. (2016). Contribution of the Endocrine Perspective in the Evaluation of Endocrine Disrupting Chemical Effects: The Case Study of Pubertal Timing. Hormone research in paediatrics, 86(4), 221-232. https://doi.org/10.1159/000442748
Skakkebaek, N. E., Rajpert-De Meyts, E., Buck Louis, G. M., Toppari, J., Andersson, A-M., Eisenberg, M. L., ... Juul, A. (2016). Male Reproductive Disorders and Fertility Trends: Influences of Environment and Genetic Susceptibility. Physiological Reviews, 96(1), 55-97. https://doi.org/10.1152/physrev.00017.2015
Hvid, T., Åkerstrøm, T., Nielsen, S., Yfanti, C., Juul, A., Lindegaard, B., ... Hojman, P. (2016). Pre-training levels of testosterone and sex hormone-binding globulin are not correlated with training adaptations in fat mass and insulin sensitivity in healthy young men. Endocrine, 52(3), 660-3. https://doi.org/10.1007/s12020-015-0771-y
Känsäkoski, J., Raivio, T., Juul, A., & Tommiska, J. (2015). A missense mutation in MKRN3 in a Danish girl with central precocious puberty and her brother with early puberty. Pediatric Research, 78(6), 709-11. [78]. https://doi.org/10.1038/pr.2015.159
Jensen, R. B., Juul, A., Larsen, T., Mortensen, E. L., & Greisen, G. (2015). Cognitive ability in adolescents born small for gestational age: Associations with fetal growth velocity, head circumference and postnatal growth. Early Human Development, 91(12), 755-60. https://doi.org/10.1016/j.earlhumdev.2015.08.014
Ringholm, L., Juul, A., Pedersen-Bjergaard, U., Thorsteinsson, B., Damm, P., & Mathiesen, E. R. (2015). Lower levels of placental growth hormone in early pregnancy in women with type 1 diabetes and large for gestational age infants. Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society, 25(6), 312-5. https://doi.org/10.1016/j.ghir.2015.11.002
Holmboe, S. A., Vradi, E., Kold Jensen, T., Linneberg, A., Husemoen, L. L. N., Scheike, T., ... Andersson, A-M. (2015). The association of reproductive hormone levels and all-cause, cancer and cardiovascular disease mortality in men. The Journal of clinical endocrinology and metabolism, 100(12), 4472-80. https://doi.org/10.1210/jc.2015-2460
Mieritz, M. G., Rakêt, L. L., Hagen, C. P., Nielsen, J. E., Talman, M-L. M., Petersen, J. H., ... Juul, A. (2015). A Longitudinal Study of Growth, Sex Steroids, and IGF-1 in Boys With Physiological Gynecomastia. The Journal of clinical endocrinology and metabolism, 100(10), 3752-9. https://doi.org/10.1210/jc.2015-2836
Jørgensen, A., Lindhardt Johansen, M., Juul, A., Skakkebaek, N. E., Main, K. M., & Rajpert-De Meyts, E. (2015). Pathogenesis of germ cell neoplasia in testicular dysgenesis and disorders of sex development. Seminars in Cell and Developmental Biology, 45, 124-37. https://doi.org/10.1016/j.semcdb.2015.09.013
Mouritsen, A., Søeborg, T., Hagen, C. P., Mieritz, M. G., Johannsen, T. H., Frederiksen, H., ... Juul, A. (2015). Longitudinal changes in serum concentrations of adrenal androgen metabolites and their ratios by LC-MS/MS in healthy boys and girls. Clinica chimica acta; international journal of clinical chemistry, 450, 370-5. https://doi.org/10.1016/j.cca.2015.09.020
Gundersen, T. D., Jørgensen, N., Andersson, A-M., Bang, A. K., Nordkap, L., Skakkebæk, N. E., ... Jensen, T. K. (2015). Association Between Use of Marijuana and Male Reproductive Hormones and Semen Quality: A Study Among 1,215 Healthy Young Men. American Journal of Epidemiology, 182(6), 473-81. https://doi.org/10.1093/aje/kwv135
Boehm, U., Bouloux, P-M., Dattani, M. T., de Roux, N., Dodé, C., Dunkel, L., ... Young, J. (2015). European Consensus Statement on congenital hypogonadotropic hypogonadism —pathogenesis, diagnosis and treatment. Nature reviews. Endocrinology, 11(9), 547-64. https://doi.org/10.1038/nrendo.2015.112
Jørgensen, A., Nielsen, J. E., Perlman, S., Lundvall, L., Mitchell, R. T., Juul, A., & Rajpert-De Meyts, E. (2015). Ex vivo culture of human fetal gonads: manipulation of meiosis signalling by retinoic acid treatment disrupts testis development. Human reproduction (Oxford, England), 30(10), 2351-63. https://doi.org/10.1093/humrep/dev194
Sørensen, K., & Juul, A. (2015). BMI percentile-for-age overestimates adiposity in early compared with late maturing pubertal children. European journal of endocrinology / European Federation of Endocrine Societies, 173(2), 227-35. https://doi.org/10.1530/EJE-15-0239
Hagen, C. P., Mouritsen, A., Mieritz, M. G., Tinggaard, J., Wohlfahrt-Veje, C., Fallentin, E., ... Main, K. M. (2015). Uterine volume and endometrial thickness in healthy girls evaluated by ultrasound (3-dimensional) and magnetic resonance imaging. Fertility and Sterility, 104(2), 452-459.e2. https://doi.org/10.1016/j.fertnstert.2015.04.042
Lunding, S. A., Aksglaede, L., Anderson, R. A., Main, K. M., Juul, A., Hagen, C. P., & Pedersen, A. T. (2015). AMH as Predictor of Premature Ovarian Insufficiency: A Longitudinal Study of 120 Turner Syndrome Patients. The Journal of clinical endocrinology and metabolism, 100(7), E1030-8. https://doi.org/10.1210/jc.2015-1621
Poulsen, G. L., Nielsen, J. E., Skakkebæk, N. E., Juul, A., & Rajpert-De Meyts, E. (2015). Abundance of DLK1, differential expression of CYP11B1, CYP21A2 and MC2R, and lack of INSL3 distinguish testicular adrenal rest tumours from Leydig cell tumours. European journal of endocrinology / European Federation of Endocrine Societies, 172(4), 491-9. https://doi.org/10.1530/EJE-14-0810
Hauser, R., Skakkebaek, N. E., Hass, U., Toppari, J., Juul, A., Andersson, A-M., ... Trasande, L. (2015). Male Reproductive Disorders, Diseases, and Costs of Exposure to Endocrine-Disrupting Chemicals in the European Union. The Journal of clinical endocrinology and metabolism, 100(4), 1267-77. https://doi.org/10.1210/jc.2014-4325
Hagen, C. P., Sørensen, K., Mieritz, M. G., Johannsen, T. H., Almstrup, K., & Juul, A. (2015). Circulating MKRN3 Levels Decline Prior to Pubertal Onset and Through Puberty: A Longitudinal Study of Healthy Girls. The Journal of clinical endocrinology and metabolism, 100(5), 1920-6. https://doi.org/10.1210/jc.2014-4462
Allen, D. B., Backeljauw, P., Bidlingmaier, M., Biller, B. M. K., Boguszewski, M., Burman, P., ... Thorner, M. (2015). GH safety workshop position paper: a critical appraisal of recombinant human GH therapy in children and adults. European journal of endocrinology / European Federation of Endocrine Societies, 174(2), P1-9. https://doi.org/10.1530/EJE-15-0873
Lawaetz, J. G., Hagen, C. P., Grunnet Mieritz, M., Blomberg Jensen, M., Holm Petersen, J., & Juul, A. (2015). Evaluation of 451 Danish Boys with Delayed Puberty: Diagnostic use of a new Puberty Nomogram and Effects of Oral Testosterone Therapy. The Journal of clinical endocrinology and metabolism, 100(4), 1376-85. https://doi.org/10.1210/jc.2014-3631
Winge, S. B., Nielsen, J., Jørgensen, A., Owczarek, S., Ewen, K. A., Nielsen, J. E., ... Rajpert-De Meyts, E. (2015). Biglycan is a novel binding partner of fibroblast growth factor receptor 3c (FGFR3c) in the human testis. Molecular and Cellular Endocrinology, 399, 235-43. https://doi.org/10.1016/j.mce.2014.09.018
Hagen, C. P., Mouritsen, A., Mieritz, M. G., Tinggaard, J., Wohlfart-Veje, C., Fallentin, E., ... Main, K. M. (2015). Circulating AMH reflects ovarian morphology by Magnetic Resonance Imaging and 3D-ultrasound in 121 healthy girls. The Journal of clinical endocrinology and metabolism, 100(3), 880-90. https://doi.org/10.1210/jc.2014-3336
Faurschou, S., Mouritsen, A., Johannsen, T. H., Hougaard, D. M., Cohen, A., Duno, M., ... Main, K. M. (2015). Hormonal disturbances due to severe and mild forms of congenital adrenal hyperplasia are already detectable in neonatal life. Acta paediatrica, 104(2), e57-62. https://doi.org/10.1111/apa.12835
Hagen, C. P., Mieritz, M. G., Nielsen, J. E., Anand-Ivell, R., Ivell, R., & Juul, A. (2015). Longitudinal assessment of circulating insulin-like peptide 3 levels in healthy peripubertal girls. Fertility and Sterility, 103(3), 780-86e.1. https://doi.org/10.1016/j.fertnstert.2014.11.014
Blomberg Jensen, M., Priskorn, L., Jensen, T. K., Juul, A., & Skakkebaek, N. E. (2015). Temporal Trends in Fertility Rates: A Nationwide Registry Based Study from 1901 to 2014. P L o S One, 10(12), e0143722. https://doi.org/10.1371/journal.pone.0143722
Beck Jensen, R., Thankamony, A., Day, F., Scott, R. A., Langenberg, C., Kirk, J., ... Dunger, D. B. (2014). Genetic markers of insulin sensitivity and insulin secretion are associated with spontaneous postnatal growth and response to growth hormone treatment in short SGA children: the North European SGA Study (NESGAS). The Journal of clinical endocrinology and metabolism, jc20143469. https://doi.org/10.1210/jc.2014-3469
Tinggaard, J., Jensen, R. B., Sundberg, K., Birkebæk, N., Christiansen, P., Ellermann, A., ... Juul, A. (2014). Ovarian morphology and function during growth hormone therapy of short girls born small for gestational age. Fertility and Sterility, 102(6), 1733-41. https://doi.org/10.1016/j.fertnstert.2014.09.014
Søeborg, T., Frederiksen, H., Mouritsen, A., Johannsen, T. H., Main, K. M., Jørgensen, N., ... Juul, A. (2014). Sex, age, pubertal development and use of oral contraceptives in relation to serum concentrations of DHEA, DHEAS, 17α-hydroxyprogesterone, Δ4-androstenedione, testosterone and their ratios in children, adolescents and young adults. Clinica chimica acta; international journal of clinical chemistry, 437, 6-13. https://doi.org/10.1016/j.cca.2014.06.018
Vestergaard, P. F., Vendelbo, M. H., Pedersen, S. B., Juul, A., Ringgard, S., Møller, N., ... Jørgensen, J. O. L. (2014). GH signaling in skeletal muscle and adipose tissue in healthy human subjects: impact of gender and age. European journal of endocrinology / European Federation of Endocrine Societies, 171(5), 623-31. https://doi.org/10.1530/EJE-14-0538
Jensen, R. B., Thankamony, A., O'Connell, S. M., Kirk, J., Donaldson, M., Ivarsson, S-A., ... Juul, A. (2014). A randomised controlled trial evaluating IGF1 titration in contrast to current GH dosing strategies in children born small for gestational age: the North European Small-for-Gestational-Age Study. European journal of endocrinology / European Federation of Endocrine Societies, 171(4), 509-18. https://doi.org/10.1530/EJE-14-0419
Mieritz, M. G., Sorensen, K., Aksglaede, L., Mouritsen, A., Hagen, C. P., Hilsted, L., ... Juul, A. (2014). Elevated serum levels of free triiodothyronine in adolescent boys with gynaecomastia compared with controls. European journal of endocrinology / European Federation of Endocrine Societies, 171(2), 193-8. https://doi.org/10.1530/EJE-13-0847
Tommiska, J., Känsäkoski, J., Christiansen, P., Jørgensen, N., Lawaetz, J. G., Juul, A., & Raivio, T. (2014). Genetics of congenital hypogonadotropic hypogonadism in Denmark. European Journal of Medical Genetics, 57(7), 345-8. https://doi.org/10.1016/j.ejmg.2014.04.002
Juul, A., Almstrup, K., Andersson, A-M., Jensen, T. K., Jørgensen, N., Main, K. M., ... Skakkebæk, N. E. (2014). Possible fetal determinants of male infertility. Nature reviews. Endocrinology, 10, 553-562. https://doi.org/10.1038/nrendo.2014.97
Thankamony, A., Capalbo, D., Marcovecchio, M. L., Sleigh, A., Jørgensen, S. W., Hill, N. R., ... Dunger, D. B. (2014). Low circulating levels of IGF-1 in healthy adults are associated with reduced β-cell function, increased intramyocellular lipid, and enhanced fat utilization during fasting. The Journal of clinical endocrinology and metabolism, 99(6), 2198-207. https://doi.org/10.1210/jc.2013-4542
Lassen, T. H., Frederiksen, H., Jensen, T. K., Petersen, J. H., Joensen, U. N., Main, K. M., ... Andersson, A-M. (2014). Urinary bisphenol A levels in young men: association with reproductive hormones and semen quality. Environmental Health Perspectives, 122(5), 478-84. https://doi.org/10.1289/ehp.1307309
Lindhardt Johansen, M., Anand-Ivell, R., Mouritsen, A., Hagen, C. P., Mieritz, M. G., Søeborg, T., ... Juul, A. (2014). Serum levels of INSL3, AMH, Inhibin B and Testosterone during pubertal transition in healthy boys. Reproduction (Cambridge, England), 147, 529-535. https://doi.org/10.1530/REP-13-0435
Frederiksen, H., Jensen, T. K., Jørgensen, N., Boye Kyhl, H., Husby, S., Skakkebaek, N. E., ... Andersson, A-M. (2014). Human urinary excretion of non-persistent environmental chemicals: an overview of Danish data collected 2006-2012. Reproduction (Cambridge, England), 147, 555-565. https://doi.org/10.1530/REP-13-0522
Rossing, M., Gerdes, A-M., Juul, A., Rechnitzer, C., Rudnicki, M., Nielsen, F. C., & Hansen, T. V. O. (2014). A novel DICER1 mutation identified in a female with ovarian Sertoli-Leydig cell tumor and multinodular goiter: a case report. Journal of Medical Case Reports, 8, 112. https://doi.org/10.1186/1752-1947-8-112
Harder-Lauridsen, N. M., Birk, N. M., Ried-Larsen, M., Juul, A., Andersen, L. B., Pedersen, B. K., & Krogh-Madsen, R. (2014). A randomized controlled trial on a multicomponent intervention for overweight school-aged children - Copenhagen, Denmark. B M C Pediatrics, 14(1), 273. https://doi.org/10.1186/1471-2431-14-273
Andreassen, M., Jensen, R. B., Jørgensen, N., & Juul, A. (2014). Association between GH receptor polymorphism (exon 3 deletion), serum IGF1, semen quality, and reproductive hormone levels in 838 healthy young men. European journal of endocrinology / European Federation of Endocrine Societies, 170(4), 555-563. https://doi.org/10.1530/EJE-13-0729
Mouritsen, A., Lindhardt Johansen, M., Wohlfart-Veje, C., Hagen, C. P., Tinggaard, J., Mieritz, M. G., ... Main, K. M. (2014). Determination of Adrenal Volume by MRI in Healthy Children: Associations to Age, Body Size, Pubertal Stage and Serum levels of Adrenal Androgens. Clinical Endocrinology, 81, 183-189. https://doi.org/10.1111/cen.12414
Mieritz, M. G., Sørensen, K., Aksglæde, L., Mouritsen, A., Hagen, C. P., Hilsted, L., ... Juul, A. (2014). Elevated serum IGF-I, but unaltered sex steroid levels, in Healthy Boys with Pubertal Gynaecomastia. Clinical Endocrinology, 80(5), 691-8. https://doi.org/10.1111/cen.12323
Bliddal, S., Feldt-Rasmussen, U., Boas, M., Faber, J., Juul, A., Larsen, T. K., & Precht, D. H. (2014). Gestational-age-specific reference ranges from different laboratories misclassifies pregnant women's thyroid status: comparison of two longitudinal prospective cohort studies. European journal of endocrinology / European Federation of Endocrine Societies, 170, 329-39. https://doi.org/10.1530/EJE-13-0672
Jensen, T. K., Gottschau, M. E., Madsen, J. O. B., Andersson, A-M., Lassen, T. H., Skakkebæk, N. E., ... Jørgensen, N. (2014). Habitual alcohol consumption associated with reduced semen quality and changes in reproductive hormones; a cross-sectional study among 1221 young Danish men. B M J Open, 4(9), e005462. https://doi.org/10.1136/bmjopen-2014-005462
Mouritsen, A., Søeborg, T., Johannsen, T. H., Aksglaede, L., Sørensen, K., Hagen, C. P., ... Juul, A. (2014). Longitudinal changes in circulating testosterone levels determined by LC-MS/MS and by a commercially available radioimmunoassay in healthy girls and boys during the pubertal transition. Hormone Research in Paediatrics, 82(1), 12-7. https://doi.org/10.1159/000358560
Wohlfart-Veje, C., Audouze, K. M. L., Brunak, S., Antignac, J. P., le Bizec, B., Juul, A., ... Main, K. M. (2014). Polychlorinated dibenzo-p-dioxins, furans, and biphenyls (PCDDs/PCDFs and PCBs) in breast milk and early childhood growth and IGF1. Reproduction (Cambridge, England), 147(4), 391-9. https://doi.org/10.1530/REP-13-0422
Hagen, C. P., Sørensen, K., Aksglaede, L., Mouritsen, A., Mieritz, M. G., Tinggaard, J., ... Juul, A. (2014). Pubertal Onset in Girls is Strongly Influenced by Genetic Variation Affecting FSH Action. Scientific Reports, 4, 6412. https://doi.org/10.1038/srep06412
Bisgaard, A., Sørensen, K., Johannsen, T. H., Helge, J. W., Andersson, A-M., & Juul, A. (2014). Significant gender difference in serum levels of fibroblast growth factor 21 in Danish children and adolescents. International journal of pediatric endocrinology, 2014(1), 7. https://doi.org/10.1186/1687-9856-2014-7
Tinggaard, J., Aksglaede, L., Sørensen, K., Mouritsen, A., Wohlfart-Veje, C., Hagen, C. P., ... Juul, A. (2014). The 2014 Danish references from birth to 20 years for height, weight and body mass index. Acta paediatrica, 103(2), 214-24. https://doi.org/10.1111/apa.12468
Molgaard-Hansen, L., Skou, A-S., Juul, A., Glosli, H., Jahnukainen, K., Jarfelt, M., ... Nordic Society of Pediatric Hematology and Oncology (NOPHO) (2013). Pubertal development and fertility in survivors of childhood acute myeloid leukemia treated with chemotherapy only: A NOPHO-AML study. Pediatric Blood & Cancer, 60(12), 1988-95. https://doi.org/10.1002/pbc.24715
Sørensen, K., Juul, A., Christensen, K., Skytthe, A., Scheike, T. H., & Kold Jensen, T. (2013). Birth size and age at menarche: a twin perspective. Human reproduction (Oxford, England), 28(10), 2865-71. https://doi.org/10.1093/humrep/det283
Blomberg Jensen, M., Lieben, L., Nielsen, J. E., Willems, A., Jørgensen, A., Juul, A., ... Rajpert-De Meyts, E. (2013). Characterization of the testicular, epididymal and endocrine phenotypes in the Leuven Vdr-deficient mouse model: targeting estrogen signalling. Molecular and Cellular Endocrinology, 377(1-2), 93-102. https://doi.org/10.1016/j.mce.2013.06.036
Mouritsen, A., Frederiksen, H., Sørensen, K., Aksglæde, L., Hagen, C., Skakkebæk, N. E., ... Juul, A. (2013). Urinary phthalates from 168 girls and boys measured twice a year during a 5-year period: associations with adrenal androgen levels and puberty. Journal of Clinical Endocrinology and Metabolism, 98(9), 3755-64. https://doi.org/10.1210/jc.2013-1284
Hagen, C. P., Aksglæde, L., Sørensen, K., Mouritsen, A., Mieritz, M. G., Main, K. M., ... Juul, A. (2013). FSHB-211 and FSHR 2039 are associated with serum levels of follicle-stimulating hormone and antimüllerian hormone in healthy girls: a longitudinal cohort study. Fertility and Sterility, 100(4), 1089-1095. https://doi.org/10.1016/j.fertnstert.2013.06.026
Andreassen, M., Frystyk, J., Faber, J., Kristensen, L. Ø., & Juul, A. (2013). Growth hormone (GH) activity is associated with increased serum oestradiol and reduced Anti-Müllerian Hormone in healthy male volunteers treated with GH and a GH antagonist. Andrology, 1(4), 595-601. https://doi.org/10.1111/j.2047-2927.2013.00096.x
Abildgaard, J., Pedersen, A. T., Green, C. J., Majlund Harder-Lauridsen, N., Solomon, T. P., Thomsen, C., ... Lindegaard, B. (2013). Menopause is associated with decreased whole body fat oxidation during exercise. American Journal of Physiology: Endocrinology and Metabolism, 304(11), E1227-36. https://doi.org/10.1152/ajpendo.00492.2012
Munch-Andersen, T., Sorensen, K., Andersen, L. B., Aachmann-Andersen, N. J., Aksglaede, L., Juul, A., & Helge, J. W. (2013). Adverse metabolic risk profiles in Greenlandic Inuit children compared to Danish children. Obesity (Silver Spring, Md.), 21(6), 1226-31. https://doi.org/10.1002/oby.20203
Andersen, P. S., Petersen, B. L., Juul, A., & Andersen, M. (2013). Prepubertal unilateral gynecomastia and the presence of 47,XXY mosaicism in breast epithelial cells: a case report. Journal of Pediatric Surgery, 48(2), e21-3. https://doi.org/10.1016/j.jpedsurg.2012.11.051
Mouritsen, A., Aksglæde, L., Sørensen, K., Hagen, C. P., Petersen, J. H., Main, K. M., & Juul, A. (2013). The pubertal transition in 179 healthy Danish children: associations between pubarche, adrenarche, gonadarche, and body composition. European Journal of Endocrinology, 168(2), 129-36. https://doi.org/10.1530/EJE-12-0191
Aksglæde, L., Link, K., Giwercman, A., Jørgensen, N., Skakkebæk, N. E., & Juul, A. (2013). 47,XXY Klinefelter syndrome: clinical characteristics and age-specific recommendations for medical management. American Journal of Medical Genetics. Part C: Seminars in Medical Genetics, 163(1), 55-63. https://doi.org/10.1002/ajmg.c.31349
Tommiska, J., Jørgensen, N., Christiansen, P., Juul, A., & Raivio, T. (2013). A homozygous R262Q mutation in the gonadotropin-releasing hormone receptor presenting as reversal of hypogonadotropic hypogonadism and late-onset hypogonadism. Clinical Endocrinology, 78(2), 316-7. https://doi.org/10.1111/j.1365-2265.2012.04493.x
Mouritsen, A., Hagen, C. P., Sørensen, K., Aksglæde, L., Mieritz, M. G., Main, K. M., ... Juul, A. (2013). Androgen Receptor CAG Repeat Length Is Associated With Body Fat and Serum SHBG in Boys: A Prospective Cohort Study. Journal of Clinical Endocrinology and Metabolism, 98(3), E605-9. https://doi.org/10.1210/jc.2012-3778
Lindhardt Johansen, M., Hagen, C. P., Johannsen, T. H., Main, K. M., Picard, J-Y., Jørgensen, A., ... Juul, A. (2013). Anti-Müllerian Hormone and Its Clinical Use in Pediatrics with Special Emphasis on Disorders of Sex Development. International Journal of Endocrinology, 2013, 198698. https://doi.org/10.1155/2013/198698
Jensen, R. B., Thankamony, A., O'Connell, S. M., Salgin, B., Kirk, J., Donaldson, M., ... Juul, A. (2013). Baseline IGF-I Levels Determine Insulin Secretion and Insulin Sensitivity during the First Year on Growth Hormone Therapy in Children Born Small for Gestational Age. Results from a North European Multicentre Study (NESGAS). Hormone Research in Paediatrics, 80(1), 38-46. https://doi.org/10.1159/000353438
Frederiksen, H., Aksglæde, L., Sørensen, K., Nielsen, O., Main, K. M., Skakkebæk, N. E., ... Andersson, A-M. (2013). Bisphenol A and other phenols in urine from Danish children and adolescents analyzed by isotope diluted TurboFlow-LC-MS/MS. International Journal of Hygiene and Environmental Health, 216, 710-720. https://doi.org/10.1016/j.ijheh.2013.01.007
Østergren, P., Juul, A., & Azawi, N. H. (2013). Disorders of sex development presenting as unilateral cryptorchidism. Scandinavian Journal of Urology and Nephrology, 47(5), 433-36. https://doi.org/10.3109/21681805.2013.766901
Munch-Andersen, T., Sorensen, K., Aachmann-Andersen, N. J., Aksglaede, L., Juul, A., & Helge, J. W. (2013). Ethnic differences in leptin and adiponectin levels between Greenlandic Inuit and Danish children. International Journal of Circumpolar Health, 72. https://doi.org/10.3402/ijch.v72i0.21458
Ewen, K. A., Olesen, I. A., Winge, S. B., Nielsen, A. R., Nielsen, J. E., Graem, N., ... Rajpert-De Meyts, E. (2013). Expression of FGFR3 during human testis development and in germ cell-derived tumours of young adults. International Journal of Developmental Biology, 57(2-4), 141-51. https://doi.org/10.1387/ijdb.130022er
Edsgärd, D., Dalgaard, M. D., Weinhold, N., Wesolowska-Andersen, A., Rajpert-De Meyts, E., Ottesen, A-M., ... Brunak, S. (2013). Genome-wide assessment of the association of rare and common copy number variations to testicular germ cell cancer. Frontiers in Endocrinology, 4, 2. https://doi.org/10.3389/fendo.2013.00002
Nielsen, J., Jensen, R. B., & Juul, A. (2013). Increased sex hormone-binding globulin levels in children and adolescents with thyrotoxicosis. Hormone Research in Paediatrics, 79, 157-61. https://doi.org/10.1159/000348837
Jørgensen, A., Blomberg Jensen, M., Nielsen, J. E., Juul, A., & Rajpert-De Meyts, E. (2013). Influence of vitamin D on cisplatin sensitivity in testicular germ cell cancer-derived cell lines and in a NTera2 xenograft model. Journal of Steroid Biochemistry and Molecular Biology, 136, 238-246. https://doi.org/10.1016/j.jsbmb.2012.10.008
Hilsted, L., Rustad, P., Aksglæde, L., Sørensen, K., & Juul, A. (2013). Recommended Nordic paediatric reference intervals for 21 common biochemical properties. Scandinavian Journal of Clinical & Laboratory Investigation, 73(1), 1-9. https://doi.org/10.3109/00365513.2012.721519
Bergman, Å., Andersson, A-M., Becher, G., van den Berg, M., Blumberg, B., Bjerregaard, P., ... Zoeller, R. T. (2013). Science and policy on endocrine disrupters must not be mixed: a reply to a "common sense" intervention by toxicology journal editors. Environmental Health: A Global Access Science Source, 12, 69. https://doi.org/10.1186/1476-069X-12-69
Søeborg, T., Frederiksen, H., Fruekilde, P., Johannsen, T. H., Juul, A., & Andersson, A. M. (2013). Serum concentrations of DHEA, DHEAS, 17α-hydroxyprogesterone, Δ4-androstenedione and testosterone in children determined by TurboFlow-LC-MS/MS. Clinica Chimica Acta, 419C, 95-101. https://doi.org/10.1016/j.cca.2013.01.019
Bang, A. K., Jørgensen, N., Rajpert-De Meyts, E., & Juul, A. (2013). UGT2B17 Genotype and the Pharmacokinetic Serum Profile of Testosterone during Substitution Therapy with Testosterone Undecanoate. A Retrospective Experience from 207 Men with Hypogonadism. Frontiers in Endocrinology, 4, 94. https://doi.org/10.3389/fendo.2013.00094
Færch, L., Juul, A., Pedersen-Bjergaard, U., & Thorsteinsson, B. (2012). Association of IGF1 with glycemic control and occurrence of severe hypoglycemia in patients with type 1 diabetes mellitus. Endocrine Connections, 1(1), 31-6. https://doi.org/10.1530/EC-12-0012
Lindhardt Johansen, M., Hagen, C. P., Rajpert-De Meyts, E., Kjærgaard, S., Petersen, B. L., Skakkebæk, N. E., ... Juul, A. (2012). 45,X/46,XY mosaicism: phenotypic characteristics, growth, and reproductive function--a retrospective longitudinal study. Journal of Clinical Endocrinology and Metabolism, 97(8), E1540-9. https://doi.org/10.1210/jc.2012-1388
Dalgaard, M. D., Weinhold, N., Edsgärd, D., Silver, J. D., Pers, T. H., Nielsen, J. E., ... Gupta, R. (2012). A genome-wide association study of men with symptoms of testicular dysgenesis syndrome and its network biology interpretation. Journal of Medical Genetics, 49(1), 58-65. https://doi.org/10.1136/jmedgenet-2011-100174
Johannsen, T. H., Søeborg, T., Frederiksen, H., Andersson, A-M., & Juul, A. (2012). androgenstatus: metode og klinisk anvendelse. Klinisk Kemi i Norden, 24(3), 10-17.
Nielsen, L. B., Wang, C., Sørensen, K., Bang-Berthelsen, C. H., Hansen, L., Andersen, M. L. M., ... Mortensen, H. B. (2012). Circulating levels of microRNA from children with newly diagnosed type 1 diabetes and healthy controls: evidence that miR-25 associates to residual beta-cell function and glycaemic control during disease progression. Experimental Diabetes Research, 2012, 896362. https://doi.org/10.1155/2012/896362
Aksglaede, L., Garn, I. D., Hollegaard, M. V., Hougaard, D. M., Rajpert-De Meyts, E., & Juul, A. (2012). Detection of increased gene copy number in DNA from dried blood spot samples allows efficient screening for Klinefelter syndrome. Acta paediatrica, 101(12), e561-3. https://doi.org/10.1111/apa.12008
Veje, C. W., Andersen, H. R., Schmidt, I. M., Aksglaede, L., Sørensen, K., Juul, A., ... Main, K. M. (2012). Early breast development in girls after prenatal exposure to non-persistent pesticides. International Journal of Andrology, 35(3), 273-82. https://doi.org/10.1111/j.1365-2605.2011.01244.x
Blomberg Jensen, M., Jørgensen, A., Nielsen, J. E., Bjerrum, P. J., Skalkam, M., Petersen, J. H., ... Jørgensen, N. (2012). Expression of the vitamin D metabolizing enzyme CYP24A1 at the annulus of human spermatozoa may serve as a novel marker of semen quality. International Journal of Andrology, 35, 499-510. https://doi.org/10.1111/j.1365-2605.2012.01256.x
Frederiksen, H., Sørensen, K., Mouritsen, A., Aksglaede, L., Hagen, C., Petersen, J. H., ... Juul, A. (2012). High urinary phthalate concentration associated with delayed pubarche in girls. International Journal of Andrology, 35, 216-226. https://doi.org/10.1111/j.1365-2605.2012.01260.x
Jørgensen, N., Joensen, U. N., Jensen, T. K., Jensen, M. B., Almstrup, K., Olesen, I. A., ... Skakkebæk, N. E. (2012). Human semen quality in the new millennium: a prospective cross-sectional population-based study of 4867 men. BMJ Open, 2(4), e000990. https://doi.org/10.1136/bmjopen-2012-000990
Hagen, C. P., Aksglaede, L., Sørensen, K., Mouritsen, A., Andersson, A-M., Petersen, J. H., ... Juul, A. (2012). Individual serum levels of anti-Müllerian hormone in healthy girls persist through childhood and adolescence: a longitudinal cohort study. Human Reproduction, 27(3), 861-6. https://doi.org/10.1093/humrep/der435
Friedrich, N., Jørgensen, T., Juul, A., Spielhagen, C., Nauck, M., Wallaschofski, H., & Linneberg, A. (2012). Insulin-like growth factor I and anthropometric parameters in a Danish population. Experimental and Clinical Endocrinology and Diabetes, 120(3), 171-4. https://doi.org/10.1055/s-0031-1301289
Hagen, C. P., Vestergaard, S., Juul, A., Skakkebæk, N. E., Andersson, A-M., Main, K. M., ... Jensen, T. K. (2012). Low concentration of circulating antimüllerian hormone is not predictive of reduced fecundability in young healthy women: a prospective cohort study. Fertility and Sterility, 98(6), 1602-8.e2. https://doi.org/10.1016/j.fertnstert.2012.08.008
Hellmann, P., Christiansen, P., Johannsen, T. H., Main, K. M., Duno, M., & Juul, A. (2012). Male patients with partial androgen insensitivity syndrome: a longitudinal follow-up of growth, reproductive hormones and the development of gynaecomastia. Archives of Disease in Childhood, 97(5), 403-9. https://doi.org/10.1136/archdischild-2011-300584
Mogensen, S. S., Aksglaede, L., Mouritsen, A., Sørensen, K., Main, K. M., Gideon, P., & Juul, A. (2012). Pathological and incidental findings on brain MRI in a single-center study of 229 consecutive girls with early or precocious puberty. P L o S One, 7(1), e29829. https://doi.org/10.1371/journal.pone.0029829
Grandjean, P., Grønlund, C., Kjær, I. M., Jensen, T. K., Sørensen, N., Andersson, A-M., ... Weihe, P. (2012). Reproductive hormone profile and pubertal development in 14-year-old boys prenatally exposed to polychlorinated biphenyls. Reproductive Toxicology, 34(4), 498-503. https://doi.org/10.1016/j.reprotox.2012.07.005
Sørensen, K., Aksglaede, L., Petersen, J. H., Andersson, A-M., & Juul, A. (2012). Serum IGF1 and insulin levels in girls with normal and precocious puberty. European Journal of Endocrinology, 166(5), 903-10. https://doi.org/10.1530/EJE-12-0106
Hagen, C. P., Sørensen, K., Anderson, R. A., & Juul, A. (2012). Serum levels of antimüllerian hormone in early maturing girls before, during, and after suppression with GnRH agonist. Fertility and Sterility, 98(5), 1326-30. https://doi.org/10.1016/j.fertnstert.2012.07.1118
Friedrich, N., Thuesen, B., Jørgensen, T., Juul, A., Spielhagen, C., Wallaschofksi, H., & Linneberg, A. (2012). The Association Between IGF-I and Insulin Resistance: A general population study in Danish adults. Diabetes Care, 35(4), 768-773 . https://doi.org/10.2337/dc11-1833
Bonefeld, K., Hobolth, L., Juul, A., & Møller, S. (2012). The insulin like growth factor system in cirrhosis. Relation to changes in body composition following adrenoreceptor blockade. Growth Hormone & IGF Research, 22(6), 212-218. https://doi.org/10.1016/j.ghir.2012.09.001
Mieritz, M. G., Frederiksen, H., Sørensen, K., Aksglaede, L., Mouritsen, A., Hagen, C. P., ... Juul, A. (2012). Urinary phthalate excretion in 555 healthy Danish boys with and without pubertal gynaecomastia. International Journal of Andrology, 35(3), 227-35. https://doi.org/10.1111/j.1365-2605.2012.01279.x
Blomberg Jensen, M., Jørgensen, A., Nielsen, J. E., Steinmeyer, A., Leffers, H., Juul, A., & Rajpert-De Meyts, E. (2012). Vitamin D metabolism and effects on pluripotency genes and cell differentiation in testicular germ cell tumors in vitro and in vivo. Neoplasia, 14(10), 952-63.
Bandak, M., Aksglaede, L., Juul, A., Rørth, M., & Daugaard, G. (2011). The pituitary-Leydig cell axis before and after orchiectomy in patients with stage I testicular cancer. European Journal of Cancer, 47(17), 2585-91. https://doi.org/10.1016/j.ejca.2011.05.026
Vestergaard, T. R., Juul, A., Lausten-Thomsen, U., Lausen, B., Hjalgrim, H., Kvist, T. K., ... Schmiegelow, K. (2011). Duration of adrenal insufficiency during treatment for childhood acute lymphoblastic leukemia. International Journal of Pediatric Hematology/Oncology, 33(6), 442-9. https://doi.org/10.1097/MPH.0b013e3182260cbe
Roque, F. S., Jensen, P. B., Schmock, H., Dalgaard, M., Andreatta, M., Hansen, T., ... Brunak, S. (2011). Using electronic patient records to discover disease correlations and stratify patient cohorts. P L o S Computational Biology, 7(8), e1002141. https://doi.org/10.1371/journal.pcbi.1002141
Frederiksen, H., Aksglaede, L., Sørensen, K., Skakkebaek, N. E., Juul, A., & Andersson, A-M. (2011). Urinary excretion of phthalate metabolites in 129 healthy Danish children and adolescents: Estimation of daily phthalate intake. Environmental Research, 111(5), 656-63. https://doi.org/10.1016/j.envres.2011.03.005
Aksglaede, L., Skakkebaek, N. E., Almstrup, K., & Juul, A. (2011). Clinical and biological parameters in 166 boys, adolescents and adults with nonmosaic Klinefelter syndrome: a Copenhagen experience. Acta paediatrica, 100(6), 793-806. https://doi.org/10.1111/j.1651-2227.2011.02246.x
Rajpert-De Meyts, E., Ottesen, A. M., Garn, I. D., Aksglaede, L., & Juul, A. (2011). Deletions of the Y chromosome are associated with sex chromosome aneuploidy but not with Klinefelter syndrome. Acta paediatrica, 100(6), 900-2. https://doi.org/10.1111/j.1651-2227.2011.02169.x
Blomberg Jensen, M., Bjerrum, P. J., Jessen, T. E., Nielsen, J. E., Joensen, U. N., Olesen, I. A., ... Jørgensen, N. (2011). Vitamin D is positively associated with sperm motility and increases intracellular calcium in human spermatozoa. Human Reproduction, 26(6), 1307-17. https://doi.org/10.1093/humrep/der059
Mogensen, S. S., Aksglaede, L., Mouritsen, A., Sørensen, K., Main, K. M., Gideon, P., & Juul, A. (2011). Diagnostic work-up of 449 consecutive girls who were referred to be evaluated for precocious puberty. Journal of Clinical Endocrinology and Metabolism, 96(5), 1393-401. https://doi.org/10.1210/jc.2010-2745
Nielsen, L. R., Vestgaard, M., Laugesen, C. S., Juul, A., Damm, P., & Mathiesen, E. R. (2011). Pregnancy-induced increase in circulating IGF-I is associated with progression of diabetic retinopathy in women with type 1 diabetes. Growth Hormone & IGF Research, 21(1), 25-30. https://doi.org/10.1016/j.ghir.2010.12.001
Bang, P., Bjerknes, R., Dahlgren, J., Dunkel, L., Gustafsson, J., Juul, A., ... Aberg, V. (2011). A comparison of different definitions of growth response in short prepubertal children treated with growth hormone. Hormone Research in Paediatrics, 75(5), 335-45. https://doi.org/10.1159/000322878
Juul, A., Main, K. M., & Skakkebaek, N. E. (2011). Development: disorders of sex development-the tip of the iceberg? Nature reviews. Endocrinology, 7(9), 504-5. https://doi.org/10.1038/nrendo.2011.115
Jensen, R. B., vielwerth, S., Larsen, T., Hilsted, L. M., Cohen, A., Hougaard, D. M., ... Juul, A. (2011). Influence of fetal growth velocity and smallness at birth on adrenal function in adolescence. Hormone research in paediatrics, 75(1), 2-7. https://doi.org/10.1159/000315656
Tommiska, J., Sørensen, K., Aksglaede, L., Koivu, R., Puhakka, L., Juul, A., & Raivio, T. (2011). LIN28B, LIN28A, KISS1, and KISS1R in idiopathic central precocious puberty. B M C Research Notes, 4, 363. https://doi.org/10.1186/1756-0500-4-363
Hagen, C. P., Aksglæde, L., Sørensen, K., Mouritsen, A. K., & Juul, A. (2011). Clinical use of Anti-müllerian hormone (AMH) determinations in patients with disorders of sex development: importance of sex- and age-specific reference ranges. Pediatric Endocrinology Reviews, 9(suppl), 525-527.
Rasmussen, M. H., Juul, A., Main, K. M., & Hilsted, J. (2011). Normal sweat secretion despite impaired growth hormone-insulin-like growth factor-I axis in obese subjects. International Journal of Endocrinology, 2011, 493840. https://doi.org/10.1155/2011/493840
Aksglaede, L., Christiansen, P., Sørensen, K., Boas, M., Linneberg, A., Main, K. M., ... Juul, A. (2011). Serum concentrations of Anti-Müllerian Hormone (AMH) in 95 patients with Klinefelter syndrome with or without cryptorchidism. Acta paediatrica, 100(6), 839-845. https://doi.org/10.1111/j.1651-2227.2011.02148.x
Hagen, C. P., Main, K. M., Kjaergaard, S., & Juul, A. (2010). FSH, LH, inhibin B and estradiol levels in Turner syndrome depend on age and karyotype: longitudinal study of 70 Turner girls with or without spontaneous puberty. Human Reproduction, 25(12), 3134-41. https://doi.org/10.1093/humrep/deq291
Aksglaede, L., Sørensen, K., Boas, M., Mouritsen, A., Hagen, C. P., Jensen, R. B., ... Juul, A. (2010). Changes in anti-Müllerian hormone (AMH) throughout the life span: a population-based study of 1027 healthy males from birth (cord blood) to the age of 69 years. The Journal of clinical endocrinology and metabolism, 95(12), 5357-64. https://doi.org/10.1210/jc.2010-1207
Pedersen, N. G., Juul, A., Christiansen, M., Wøjdemann, K. R., & Tabor, A. (2010). Maternal serum placental growth hormone, but not human placental lactogen or insulin growth factor-1, is positively associated with fetal growth in the first half of pregnancy. Ultrasound in Obstetrics & Gynecology, 36(5), 534-41. https://doi.org/10.1002/uog.7727
Hagen, C. P., Aksglæde, L., Sørensen, K., Main, K. M., Boas, M., Cleemann, L., ... Juul, A. (2010). Serum levels of anti-Müllerian hormone as a marker of ovarian function in 926 healthy females from birth to adulthood and in 172 Turner syndrome patients. The Journal of clinical endocrinology and metabolism, 95(11), 5003-10. https://doi.org/10.1210/jc.2010-0930
Boas, M., Frederiksen, H., Feldt-Rasmussen, U., Skakkebæk, N. E., Hegedüs, L., Hilsted, L. M., ... Main, K. M. (2010). Childhood exposure to phthalates: associations with thyroid function, insulin-like growth factor I, and growth. Environmental Health Perspectives, 118(10), 1458-64. https://doi.org/10.1289/ehp.0901331
Frøkjær, V., Erritzøe, D., Juul, A., Nielsen, F. Å., Holst, K., Svarer, C., ... Knudsen, G. M. (2010). Endogenous plasma estradiol in healthy men is positively correlated with cerebral cortical serotonin 2A receptor binding. Psychoneuroendocrinology, 35(9), 1311-20. https://doi.org/10.1016/j.psyneuen.2010.03.002
Toppari, J., & Juul, A. (2010). Trends in puberty timing in humans and environmental modifiers. Molecular and Cellular Endocrinology, 324(1-2), 39-44. https://doi.org/10.1016/j.mce.2010.03.011
Hagenäs, I., Jørgensen, N., Rechnitzer, C., Sommer, P., Holm, M., Schmiegelow, K., ... Juul, A. (2010). Clinical and biochemical correlates of successful semen collection for cryopreservation from 12-18-year-old patients: a single-center study of 86 adolescents. Human Reproduction, 25(8), 2031-8. https://doi.org/10.1093/humrep/deq147
Sørensen, K., Mouritsen, A., Mogensen, S. S., Aksglaede, L., & Juul, A. (2010). Insulin sensitivity and lipid profiles in girls with central precocious puberty before and during gonadal suppression. The Journal of clinical endocrinology and metabolism, 95(8), 3736-44. https://doi.org/10.1210/jc.2010-0731
Blomberg Jensen, M., Andersen, C. B., Nielsen, J. E., Bagi, P., Jørgensen, A., Juul, A., & Leffers, H. (2010). Expression of the vitamin D receptor, 25-hydroxylases, 1alpha-hydroxylase and 24-hydroxylase in the human kidney and renal clear cell cancer. The Journal of steroid biochemistry and molecular biology, 121(1-2), 376-82. https://doi.org/10.1016/j.jsbmb.2010.03.069
Rosendahl, M., Andersen, C. Y., la Cour Freiesleben, N., Juul, A., Løssl, K., & Andersen, A. N. (2010). Dynamics and mechanisms of chemotherapy-induced ovarian follicular depletion in women of fertile age. Fertility and Sterility, 94(1), 156-66. https://doi.org/10.1016/j.fertnstert.2009.02.043
Mouritsen, A., Juul, A., & Jørgensen, N. (2010). Improvement of semen quality in an infertile man with 21-hydroxylase deficiency, suppressed serum gonadotropins and testicular adrenal rest tumours. International Journal of Andrology, 33(3), 518-20. https://doi.org/10.1111/j.1365-2605.2009.00958.x
Mouritsen, A., Jørgensen, N., Main, K. M., Schwartz, M., & Juul, A. (2010). Testicular adrenal rest tumours in boys, adolescents and adult men with congenital adrenal hyperplasia may be associated with the CYP21A2 mutation. International Journal of Andrology, 33(3), 521-7. https://doi.org/10.1111/j.1365-2605.2009.00967.x
Sørensen, K., Aksglaede, L., Petersen, J. H., Leffers, H., & Juul, A. (2010). The exon 3 deleted growth hormone receptor gene is associated with small birth size and early pubertal onset in healthy boys. The Journal of clinical endocrinology and metabolism, 95(6), 2819-26. https://doi.org/10.1210/jc.2009-2484
Ottesen, A-M., Aksglaede, L., Garn, I., Tartaglia, N., Tassone, F., Gravholt, C. H., ... Juul, A. (2010). Increased number of sex chromosomes affects height in a nonlinear fashion: a study of 305 patients with sex chromosome aneuploidy. American Journal of Medical Genetics. Part A, 152A(5), 1206-12. https://doi.org/10.1002/ajmg.a.33334
Blomberg Jensen, M., Nielsen, J. E., Jørgensen, A., Rajpert-De Meyts, E., Kristensen, D. M., Jørgensen, N., ... Leffers, H. (2010). Vitamin D receptor and vitamin D metabolizing enzymes are expressed in the human male reproductive tract. Human Reproduction, 25(5), 1303-11. https://doi.org/10.1093/humrep/deq024
Bentsen, A. H., Ansel, L., Simonneaux, V., Tena-Sempere, M., Juul, A., & Mikkelsen, J. D. (2010). Maturation of kisspeptinergic neurons coincides with puberty onset in male rats. Peptides, 31(2), 275-83. https://doi.org/10.1016/j.peptides.2009.11.017
Nielsen, A. M., Olsen, E. M., & Juul, A. (2010). New Danish reference values for height, weight and body mass index of children aged 0-5 years. Acta paediatrica, 99(2), 268-78. https://doi.org/10.1111/j.1651-2227.2009.01582.x
Courant, F., Aksglæde, L., Antignac, J-P., Monteau, F., Sørensen, K., Andersson, A-M., ... Bizec, B. L. (2010). Assessment of circulating sex steroid levels in prepubertal and pubertal boys and girls by a novel ultrasensitive gas chromatography-tandem mass spectrometry method. The Journal of clinical endocrinology and metabolism, 95(1), 82-92. https://doi.org/10.1210/jc.2009-1140
Sørensen, K., Aksglaede, L., Petersen, J. H., & Juul, A. (2010). Recent changes in pubertal timing in healthy Danish boys: associations with body mass index. The Journal of clinical endocrinology and metabolism, 95(1), 263-70. https://doi.org/10.1210/jc.2009-1478
Aksglæde, L., Sørensen, K., Boas, M., Mouritsen, A. K., Hagen, C. P., Jensen, R. B., ... Juul, A. (2010). Changes in Anti-Mullerian Hormone (AMH) throughout the Life Span: A Population-Based Study of 1027 Healthy Males from Birth (Cord Blood) to the Age of 69 Years. Journal of Clinical Endocrinology and Metabolism, 95(12), 5357-5364.
Backeljauw, P., Bang, P., Dunger, D. B., Juul, A., Le Bouc, Y., & Rosenfeld, R. (2010). Insulin-like growth factor-I in growth and metabolism. Journal of Pediatric Endocrinology & Metabolism, 23(1-2), 3-16.
Boas, M., Forman, J. L., Juul, A., Feldt-Rasmussen, U., Skakkebaek, N. E., Hilsted, L. M., ... Main, K. M. (2009). Narrow intra-individual variation of maternal thyroid function in pregnancy based on a longitudinal study on 132 women. European Journal of Endocrinology, 161(6), 903-10. https://doi.org/10.1530/EJE-09-0579
Sørensen, K., Aksglaede, L., Munch-Andersen, T., Aachmann-Andersen, N. J., Petersen, J. H., Hilsted, L. M., ... Juul, A. (2009). Sex hormone-binding globulin levels predict insulin sensitivity, disposition index, and cardiovascular risk during puberty. Diabetes Care, 32(5), 909-14. https://doi.org/10.2337/dc08-1618
Aksglaede, L., Juul, A., Olsen, L. W., & Sørensen, T. I. A. (2009). Age at puberty and the emerging obesity epidemic. P L o S One, 4(12), e8450. https://doi.org/10.1371/journal.pone.0008450
Juul, A., Sørensen, K., Aksglaede, L., Garn, I., Rajpert-De Meyts, E., Hullstein, I., ... Ottesen, A. M. (2009). A common deletion in the uridine diphosphate glucuronyltransferase (UGT) 2B17 gene is a strong determinant of androgen excretion in healthy pubertal boys. Journal of Clinical Endocrinology and Metabolism, 94(3), 1005-11. https://doi.org/10.1210/jc.2008-1984
Bjørnhart, B., Juul, A., Nielsen, S., Zak, M., Svenningsen, P., & Müller, K. (2009). Cartilage oligomeric matrix protein in patients with juvenile idiopathic arthritis: relation to growth and disease activity. Journal of Rheumatology, 36(8), 1749-54. https://doi.org/10.3899/jrheum.080942
Mikkelsen, J. D., Bentsen, A. H., Ansel, L., Simonneaux, V., & Juul, A. (2009). Comparison of the effects of peripherally administered kisspeptins. Regulatory Peptides, 152(1-3), 95-100. https://doi.org/10.1016/j.regpep.2008.10.001
Carel, J-C., Eugster, E. A., Rogol, A., Ghizzoni, L., Palmert, M. R., Antoniazzi, F., ... ESPE-LWPES GnRH Analogs Consensus Conference Group (2009). Consensus statement on the use of gonadotropin-releasing hormone analogs in children. Pediatrics Electronic Pages, 123(4), e752-62. https://doi.org/10.1542/peds.2008-1783
Larnkjaer, A., Ingstrup, H. K., Schack-Nielsen, L., Hoppe, C., Mølgaard, C., Skovgaard, I., ... Michaelsen, K. F. (2009). Early programming of the IGF-I axis: negative association between IGF-I in infancy and late adolescence in a 17-year longitudinal follow-up study of healthy subjects. Growth Hormone & I G F Research, 19(1), 82-6. https://doi.org/10.1016/j.ghir.2008.06.003
Sørensen, K., Aksglaede, L., Munch-Andersen, T., Aachmann-Andersen, N. J., Leffers, H., Helge, J. W., ... Juul, A. (2009). Impact of the growth hormone receptor exon 3 deletion gene polymorphism on glucose metabolism, lipids, and insulin-like growth factor-I levels during puberty. Journal of Clinical Endocrinology and Metabolism, 94(8), 2966-9. https://doi.org/10.1210/jc.2009-0313
Aksglaede, L., Jørgensen, N., Skakkebaek, N. E., & Juul, A. (2009). Low semen volume in 47 adolescents and adults with 47,XXY Klinefelter or 46,XX male syndrome. International Journal of Andrology, 32(4), 376-84. https://doi.org/10.1111/j.1365-2605.2008.00921.x
Aksglaede, L., Sørensen, K., Petersen, J. H., Skakkebaek, N. E., & Juul, A. (2009). Recent decline in age at breast development: the Copenhagen Puberty Study. Pediatrics Electronic Pages, 123(5), e932-9. https://doi.org/10.1542/peds.2008-2491
Thodberg, H. H., Kreiborg, S., Juul, A., & Pedersen, K. D. (2009). The BoneXpert method for automated determination of skeletal maturity. I E E E Transactions on Medical Imaging, 28(1), 52-66. https://doi.org/10.1109/TMI.2008.926067
Júlíusson, P. B., Roelants, M., Eide, G. E., Moster, D., Juul, A., Hauspie, R., ... Bjerknes, R. (2009). Vekstkurver for norske barn. Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række, 129(4), 281-6. https://doi.org/10.4045/tidsskr.09.32473
Behrendtzen, S., & Juul, A. (2008). Kemi mistænkes for at forstyrre børns pubertet. Politiken, 4-5.
Ringholm Nielsen, L., Juul, A., Pedersen-Bjergaard, U., Thorsteinsson, B., Damm, P., & Mathiesen, E. R. (2008). Lower levels of circulating IGF-I in Type 1 diabetic women with frequent severe hypoglycaemia during pregnancy. Diabetic Medicine, 25(7), 826-33. https://doi.org/10.1111/j.1464-5491.2008.02495.x
Agate, L., Mariotti, S., Elisei, R., Mossa, P., Pacini, F., Molinaro, E., ... Pinchera, A. (2008). Thyroid autoantibodies and thyroid function in subjects exposed to Chernobyl fallout during childhood: evidence for a transient radiation-induced elevation of serum thyroid antibodies without an increase in thyroid autoimmune disease. Journal of Clinical Endocrinology and Metabolism, 93(7), 2729-36. https://doi.org/10.1210/jc.2008-0060
Aksglaede, L., Skakkebaek, N. E., & Juul, A. (2008). Abnormal sex chromosome constitution and longitudinal growth: serum levels of insulin-like growth factor (IGF)-I, IGF binding protein-3, luteinizing hormone, and testosterone in 109 males with 47,XXY, 47,XYY, or sex-determining region of the Y chromosome (SRY)-positive 46,XX karyotypes. Journal of Clinical Endocrinology and Metabolism, 93(1), 169-76. https://doi.org/10.1210/jc.2007-1426
Vatten, L. J., Nilsen, T. I. L., Juul, A., Jeansson, S., Jenum, P. A., & Eskild, A. (2008). Changes in circulating level of IGF-I and IGF-binding protein-1 from the first to second trimester as predictors of preeclampsia. European Journal of Endocrinology, 158(1), 101-5. https://doi.org/10.1530/EJE-07-0386
Euling, S. Y., Herman-Giddens, M. E., Lee, P. A., Selevan, S. G., Juul, A., Sørensen, T. I. A., ... Swan, S. H. (2008). Examination of US puberty-timing data from 1940 to 1994 for secular trends: panel findings. Pediatrics (English Edition), 121 Suppl 3, S172-91. https://doi.org/10.1542/peds.2007-1813D
Crain, D. A., Janssen, S. J., Edwards, T. M., Heindel, J., Ho, S., Hunt, P., ... Guillette, L. J. (2008). Female reproductive disorders: the roles of endocrine-disrupting compounds and developmental timing. Fertility and Sterility, 90(4), 911-40. https://doi.org/10.1016/j.fertnstert.2008.08.067
Lassen, P., Sundberg, K., Juul, A., & Skibsted, L. (2008). Fetal goiter and bilateral ovarian cysts. Fetal Diagnosis and Therapy, 23(2), 132-5. https://doi.org/10.1159/000111593
Jensen, R. B., Vielwerth, S., Frystyk, J., Veldhuis, J., Larsen, T. K., Mølgaard, C., ... Juul, A. (2008). Fetal growth velocity, size in early life and adolescence, and prediction of bone mass: association to the GH-IGF axis. Journal of Bone and Mineral Research, 23(3), 439-46. https://doi.org/10.1359/jbmr.071034
Aksglaede, L., Olsen, L. W., Sørensen, T. I. A., & Juul, A. (2008). Forty years trends in timing of pubertal growth spurt in 157,000 Danish school children. P L o S One, 3(7), e2728. https://doi.org/10.1371/journal.pone.0002728
Aksglaede, L., Jensen, R. B., Carlsen, E., Kok, P., Keenan, D. M., Veldhuis, J., ... Juul, A. (2008). Increased basal and pulsatile secretion of FSH and LH in young men with 47,XXY or 46,XX karyotypes. European Journal of Endocrinology, 158(6), 803-10. https://doi.org/10.1530/EJE-07-0709
Aksglaede, L., Molgaard, C., Skakkebaek, N. E., & Juul, A. (2008). Normal bone mineral content but unfavourable muscle/fat ratio in Klinefelter syndrome. Archives of Disease in Childhood. Education and Practice Edition, 93(1), 30-4. https://doi.org/10.1136/adc.2007.120675
Rasmussen, M., Wildschiødtz, G., Juul, A., & Hilsted, J. (2008). Polysomnographic sleep, growth hormone insulin-like growth factor-I axis, leptin, and weight loss. Obesity, 16(7), 1516-21. https://doi.org/10.1038/oby.2008.249
Mau Kai, C., Juul, A., McElreavey, K., Ottesen, A. M., Garn, I. D., Main, K. M., ... Rajpert-De Meyts, E. (2008). Sons conceived by assisted reproduction techniques inherit deletions in the azoospermia factor (AZF) region of the Y chromosome and the DAZ gene copy number. Human Reproduction, 23(7), 1669-78. https://doi.org/10.1093/humrep/den124
Juul, A., Magnusdottir, S., Scheike, T., Prytz, S., & Skakkebaek, N. E. (2007). Age at voice break in Danish boys: effects of pre-pubertal body mass index and secular trend. International Journal of Andrology, 30(6), 537-42. https://doi.org/10.1111/j.1365-2605.2007.00751.x
Andersson, A-M., Jensen, T. K., Juul, A., Petersen, J. H., Jørgensen, T., & Skakkebaek, N. E. (2007). Secular decline in male testosterone and sex hormone binding globulin serum levels in Danish population surveys. Journal of Clinical Endocrinology and Metabolism, 92(12), 4696-705. https://doi.org/10.1210/jc.2006-2633
Aksglaede, L., Andersson, A-M., Jørgensen, N., Jensen, T. K., Carlsen, E., McLachlan, R. I., ... Juul, A. (2007). Primary testicular failure in Klinefelter's syndrome: the use of bivariate luteinizing hormone-testosterone reference charts. Clinical Endocrinology, 66(2), 276-81. https://doi.org/10.1111/j.1365-2265.2006.02722.x
Bjerre, P., Lindholm, J., Brennum, J., Juul, A., Kosteljanetz, M., Klose, M., & Feldt-Rasmussen, U. (2007). [Debat]: Hypofyseinsufficiens efter hovedtraumer. Ugeskrift for læger, 169(18), 1693-1694.
Ottesen, A. M., Garn, I. D., Aksglaede, L., Juul, A., & Rajpert-De Meyts, E. (2007). A simple screening method for detection of Klinefelter syndrome and other X-chromosome aneuploidies based on copy number of the androgen receptor gene. Molecular Human Reproduction, 13(10), 745-50. https://doi.org/10.1093/molehr/gam053
Klose, M., Juul, A., Struck, J., Morgenthaler, N. G., Kosteljanetz, M., & Feldt-Rasmussen, U. (2007). Acute and long-term pituitary insufficiency in traumatic brain injury: a prospective single-centre study. Clinical Endocrinology, 67(4), 598-606. https://doi.org/10.1111/j.1365-2265.2007.02931.x
Klamer, A., Skogstrand, K., Hougaard, D. M., Nørgaard-Petersen, B., Juul, A., & Greisen, G. (2007). Adiponectin levels measured in dried blood spot samples from neonates born small and appropriate for gestational age. European Journal of Endocrinology, 157(2), 189-94. https://doi.org/10.1530/EJE-06-0710
Rasmussen, M. H., Juul, A., & Hilsted, J. (2007). Effect of weight loss on free insulin-like growth factor-I in obese women with hyposomatotropism. Obesity, 15(4), 879-86. https://doi.org/10.1038/oby.2007.607
Aksglaede, L., Petersen, J. H., Main, K. M., Skakkebaek, N. E., & Juul, A. (2007). High normal testosterone levels in infants with non-mosaic Klinefelter's syndrome. European Journal of Endocrinology, 157(3), 345-50. https://doi.org/10.1530/EJE-07-0310
Klose, M. C., Juul, A., Poulsgaard, L., Kosteljanetz, M., Brennum, J., & Feldt-Rasmussen, U. F. (2007). Hypofyseinsufficiens efter hovedtraumer. Ugeskrift for Laeger, 169(3), 211-3.
Jensen, R. B., Vielwerth, S., Larsen, T. K., Greisen, G., Veldhuis, J., & Juul, A. (2007). Pituitary-gonadal function in adolescent males born appropriate or small for gestational age with or without intrauterine growth restriction. Journal of Clinical Endocrinology and Metabolism, 92(4), 1353-7. https://doi.org/10.1210/jc.2006-2348
Juul, A., Aksglaede, L., Lund, A. M., Duno, M., Skakkebaek, N. E., & Rajpert-De Meyts, E. (2007). Preserved fertility in a non-mosaic Klinefelter patient with a mutation in the fibroblast growth factor receptor 3 gene: case report. Human Reproduction, 22(7), 1907-11. https://doi.org/10.1093/humrep/dem126
Klose, M., Juul, A., Poulsgaard, L., Kosteljanetz, M., Brennum, J., & Feldt-Rasmussen, U. (2007). Prevalence and predictive factors of post-traumatic hypopituitarism. Clinical Endocrinology, 67(2), 193-201. https://doi.org/10.1111/j.1365-2265.2007.02860.x
Mau Kai, C., Main, K. M., Andersen, A. N., Loft, A., Skakkebaek, N. E., & Juul, A. (2007). Reduced serum testosterone levels in infant boys conceived by intracytoplasmic sperm injection. Journal of Clinical Endocrinology and Metabolism, 92(7), 2598-603. https://doi.org/10.1210/jc.2007-0095
Sørensen, K., Andersson, A. M., Skakkebaek, N. E., & Juul, A. (2007). Serum sex hormone-binding globulin levels in healthy children and girls with precocious puberty before and during gonadotropin-releasing hormone agonist treatment. Journal of Clinical Endocrinology and Metabolism, 92(8), 3189-96. https://doi.org/10.1210/jc.2007-0231
Jensen, R. B., Vielwerth, S., Larsen, T. K., Greisen, G., Leffers, H., & Juul, A. (2007). The presence of the d3-growth hormone receptor polymorphism is negatively associated with fetal growth but positively associated with postnatal growth in healthy subjects. Journal of Clinical Endocrinology and Metabolism, 92(7), 2758-63. https://doi.org/10.1210/jc.2007-0176
Kai, C. M., Main, K. M., Andersen, A. N., Loft, A., Chellakooty, M., Skakkebaek, N. E., & Juul, A. (2006). Serum insulin-like growth factor-I (IGF-I) and growth in children born after assisted reproduction. The Journal of clinical endocrinology and metabolism, 91(11), 4352-60. https://doi.org/10.1210/jc.2006-0701
Skakkebaek, N. E., Jørgensen, N., Main, K. M., Rajpert-De Meyts, E., Leffers, H., Andersson, A-M., ... Toppari, J. (2006). Is human fecundity declining? International Journal of Andrology, 29(1), 2-11. https://doi.org/10.1111/j.1365-2605.2005.00573.x
Chellakooty, M., Juul, A., Boisen, K. A., Damgaard, I. N., Kai, C. M., Schmidt, I. M., ... Main, K. M. (2006). A prospective study of serum insulin-like growth factor I (IGF-I) and IGF-binding protein-3 in 942 healthy infants: associations with birth weight, gender, growth velocity, and breastfeeding. Journal of Clinical Endocrinology and Metabolism, 91(3), 820-6. https://doi.org/10.1210/jc.2005-0950
Rasmussen, M. H., Juul, A., Kjems, L. L., & Hilsted, J. (2006). Effects of short-term caloric restriction on circulating free IGF-I, acid-labile subunit, IGF-binding proteins (IGFBPs)-1-4, and IGFBPs-1-3 protease activity in obese subjects. European Journal of Endocrinology, 155(4), 575-81. https://doi.org/10.1530/eje.1.02246
Aksglaede, L., Wikström, A. M., Rajpert-De Meyts, E., Dunkel, L., Skakkebaek, N. E., & Juul, A. (2006). Natural history of seminiferous tubule degeneration in Klinefelter syndrome. Human Reproduction Update, 12(1), 39-48. https://doi.org/10.1093/humupd/dmi039
Juul, A., Teilmann, G., Scheike, T. H., Hertel, N., Holm, K., Laursen, E., ... Skakkebaek, N. E. (2006). Pubertal development in Danish children: comparison of recent European and US data. International Journal of Andrology, 29(1), 247-55; discussion 286-90. https://doi.org/10.1111/j.1365-2605.2005.00556.x
Aksglaede, L., Juul, A., Leffers, H., Skakkebaek, N. E., & Andersson, A-M. (2006). The sensitivity of the child to sex steroids: possible impact of exogenous estrogens. Human Reproduction Update, 12(4), 341-9. https://doi.org/10.1093/humupd/dml018
Christesen, H. B. T., Jensen, R. B. B., Birkebaek, N. H., Hertel, N. T., Main, K. M., Mortensen, H. B., ... Juul, A. (2006). Vaeksthormonbehandling af korte børn født small for gestational age. Ugeskrift for Laeger, 168(9), 889-95.
Clayton, P. E., Cuneo, R. C., Juul, A., Monson, J. P., Shalet, S. M., Tauber, M., & European Society of Paediatric Endocrinology (2005). Consensus statement on the management of the GH-treated adolescent in the transition to adult care. European Journal of Endocrinology, 152(2), 165-70. https://doi.org/10.1530/eje.1.01829
Jensen, R. B., Jeppesen, K. A., Vielwerth, S., Michaelsen, K. F., Main, K. M., Skakkebaek, N. E., & Juul, A. (2005). Insulin-like growth factor I (IGF-I) and IGF-binding protein 3 as diagnostic markers of growth hormone deficiency in infancy. Hormone Research, 63(1), 15-21. https://doi.org/10.1159/000082456
Teilmann, G., Pedersen, C., Jensen, T. K., Skakkebaek, N. E., & Juul, A. (2005). Prevalence and incidence of precocious pubertal development in Denmark: an epidemiologic study based on national registries. Pediatrics (English Edition), 116(6), 1323-8. https://doi.org/10.1542/peds.2005-0012
Lange, M., Müller, J., Svendsen, O. L., Kastrup, K. W., Juul, A., & Feldt-Rasmussen, U. (2005). The impact of idiopathic childhood-onset growth hormone deficiency (GHD) on bone mass in subjects without adult GHD. Clinical Endocrinology, 62(1), 18-23. https://doi.org/10.1111/j.1365-2265.2004.02164.x
Chellakooty, M., Vangsgaard, K., Larsen, T., Scheike, T., Falck-Larsen, J., Legarth, J., ... Juul, A. (2004). A longitudinal study of intrauterine growth and the placental growth hormone (GH)-insulin-like growth factor I axis in maternal circulation: association between placental GH and fetal growth. Journal of Clinical Endocrinology and Metabolism, 89(1), 384-91.
Hoppe, C., Udam, T. R., Lauritzen, L., Mølgaard, C., Juul, A., & Michaelsen, K. F. (2004). Animal protein intake, serum insulin-like growth factor I, and growth in healthy 2.5-y-old Danish children. American Journal of Clinical Nutrition, 80(2), 447-52.
Hubina, E., Mersebach, H., Rasmussen, A. K., Juul, A., Sneppen, S. B., Góth, M. I., & Feldt-Rasmussen, U. (2004). Effect of growth hormone replacement therapy on pituitary hormone secretion and hormone replacement therapies in GHD adults. Hormone Research, 61(5), 211-7. https://doi.org/10.1159/000076538
Hoppe, C., Mølgaard, C., Juul, A., & Michaelsen, K. F. (2004). High intakes of skimmed milk, but not meat, increase serum IGF-I and IGFBP-3 in eight-year-old boys. European Journal of Clinical Nutrition, 58(9), 1211-6. https://doi.org/10.1038/sj.ejcn.1601948
Hoppe, C., Mølgaard, C., Thomsen, B. L. R., Juul, A., & Michaelsen, K. F. (2004). Protein intake at 9 mo of age is associated with body size but not with body fat in 10-y-old Danish children. American Journal of Clinical Nutrition, 79(3), 494-501.
Dalsgaard, M. K., Ott, P., Dela, F., Juul, A., Pedersen, B. K., Warberg, J., ... Secher, N. H. (2004). The CSF and arterial to internal jugular venous hormonal differences during exercise in humans. Experimental Physiology, 89(3), 271-7. https://doi.org/10.1113/expphysiol.2003.026922
Zimmermann-Belsing, T., Juul, A., Juul Holst, J., & Feldt-Rasmussen, U. (2004). The insulin-like growth axis in patients with autoimmune thyrotoxicosis: effect of antithyroid drug treatment. Growth Hormone & I G F Research, 14(3), 235-44. https://doi.org/10.1016/j.ghir.2003.12.015
Lønberg, U., Damm, P., Andersson, A-M., Main, K. M., Chellakooty, M., Lauenborg, J., ... Juul, A. (2003). Increase in maternal placental growth hormone during pregnancy and disappearance during parturition in normal and growth hormone-deficient pregnancies. American Journal of Obstetrics and Gynecology, 188(1), 247-51.
Jørgensen, M. H., Ott, P., Juul, A., Skakkebaek, N. E., & Michaelsen, K. F. (2003). Does breast feeding influence liver biochemistry? Journal of Pediatric Gastroenterology and Nutrition, 37(5), 559-65.
Lange, M., Feldt-Rasmussen, U., Svendsen, O. L., Kastrup, K. W., Juul, A., & Müller, J. (2003). High risk of adrenal insufficiency in adults previously treated for idiopathic childhood onset growth hormone deficiency. Journal of Clinical Endocrinology and Metabolism, 88(12), 5784-9.
Chellakooty, M., Schmidt, I. M., Haavisto, A. M., Boisen, K. A., Damgaard, I. N., Mau, C., ... Main, K. M. (2003). Inhibin A, inhibin B, follicle-stimulating hormone, luteinizing hormone, estradiol, and sex hormone-binding globulin levels in 473 healthy infant girls. Journal of Clinical Endocrinology and Metabolism, 88(8), 3515-20.
Jensen, R. B. B., Chellakooty, M., Vielwerth, S., Vaag, A., Larsen, T. K., Greisen, G., ... Juul, A. (2003). Intrauterine growth retardation and consequences for endocrine and cardiovascular diseases in adult life: does insulin-like growth factor-I play a role? Hormone Research, 60 Suppl 3, 136-48. https://doi.org/74515
Teilmann, G., & Juul, A. (2003). Pubertas praecox som følge af juvenil hypotyrose. Ugeskrift for Laeger, 165(43), 4121-3.
Juul, A. (2003). Serum levels of insulin-like growth factor I and its binding proteins in health and disease. Growth Hormone & IGF Research, 13(4), 113-70.
Parent, A-S., Teilmann, G., Juul, A., Skakkebaek, N. E., Toppari, J., & Bourguignon, J-P. (2003). The timing of normal puberty and the age limits of sexual precocity: variations around the world, secular trends, and changes after migration. Endocrine Reviews, 24(5), 668-93.
Lange, K. H. W., Lorentsen, J., Isaksson, F., Simonsen, L., Juul, A., Christensen, N. J., ... Bülow, J. (2002). Subcutaneous abdominal adipose tissue lipolysis during exercise determined by arteriovenous measurements in older women. American Geriatrics Society. Journal, 50(2), 275-81.
Lange, M., Svendsen, O. L., Skakkebaek, N. E., Müller, J., Juul, A., Schmiegelow, M., & Feldt-Rasmussen, U. (2002). An audit of the insulin-tolerance test in 255 patients with pituitary disease. European Journal of Endocrinology, 147(1), 41-7.
Juul, A., & Skakkebaek, N. E. (2002). Androgens and the ageing male. Human Reproduction Update, 8(5), 423-33.
Jørgensen, J., Nørrelund, H., Vahl, N., Juul, A., Skakkebaek, N. E., & Christiansen, J. S. (2002). Continuation of growth hormone therapy versus placebo in transition-phase patients with growth hormone deficiency: impact on body composition, insulin sensitivity, and thyroid function. Journal of Pediatric Endocrinology & Metabolism, 15 Suppl 5, 1355-60.
Juul, A., Bernasconi, S., Clayton, P. E., Kiess, W., DeMuinck-Keizer Schrama, S., & Drugs and Therapeutics Committee of the European Society for Paediatric Endocrinology (ESPE) (2002). European audit of current practice in diagnosis and treatment of childhood growth hormone deficiency. Hormone Research, 58(5), 233-41. https://doi.org/66265
Lange, K. H. W., Andersen, J. L., Beyer, N., Isaksson, F., Larsson, B., Rasmussen, M. H., ... Kjaer, M. (2002). GH administration changes myosin heavy chain isoforms in skeletal muscle but does not augment muscle strength or hypertrophy, either alone or combined with resistance exercise training in healthy elderly men. Journal of Clinical Endocrinology and Metabolism, 87(2), 513-23.
Kiess, W., Conway, G., Ritzen, M., Rosenfield, R., Bernasconi, S., Juul, A., ... Bourguignon, J-P. (2002). Induction of puberty in the hypogonadal girl--practices and attitudes of pediatric endocrinologists in Europe. Hormone Research, 57(1-2), 66-71. https://doi.org/57952
Chellakooty, M., Skibsted, L., Skouby, S. O., Andersson, A-M., Petersen, J. H., Main, K. M., ... Juul, A. (2002). Longitudinal study of serum placental GH in 455 normal pregnancies: correlation to gestational age, fetal gender, and weight. Journal of Clinical Endocrinology and Metabolism, 87(6), 2734-9.
Juul, A., Scheike, T. H., Davidsen, M., Gyllenborg, J., & Jørgensen, T. (2002). Low serum insulin-like growth factor I is associated with increased risk of ischemic heart disease: a population-based case-control study. Circulation, 106(8), 939-44.
Teilmann, G., Juul, A., Skakkebaek, N. E., & Toppari, J. (2002). Putative effects of endocrine disrupters on pubertal development in the human. Best Practice & Research: Clinical Endocrinology & Metabolism, 16(1), 105-21. https://doi.org/10.1053/beem.2002.0184
Christiansen, P., Andersson, A-M., Skakkebaek, N. E., & Juul, A. (2002). Serum inhibin B, FSH, LH and testosterone levels before and after human chorionic gonadotropin stimulation in prepubertal boys with cryptorchidism. European Journal of Endocrinology, 147(1), 95-101.
Gyllenborg, J., Rasmussen, S. L., Borch-Johnsen, K., Heitmann, B. L., Skakkebaek, N. E., & Juul, A. (2001). Cardiovascular risk factors in men: The role of gonadal steroids and sex hormone-binding globulin. Metabolism, 50(8), 882-8.
Lange, K. H., Lorentsen, J., Isaksson, F., Juul, A., Rasmussen, M. H., Christensen, N. J., ... Kjaer, M. (2001). Endurance training and GH administration in elderly women: effects on abdominal adipose tissue lipolysis. American Journal of Physiology: Endocrinology and Metabolism, 280(6), E886-97.
Lange, K. H., Isaksson, F., Rasmussen, M. H., Juul, A., Bülow, J., & Kjaer, M. (2001). GH administration and discontinuation in healthy elderly men: effects on body composition, GH-related serum markers, resting heart rate and resting oxygen uptake. Clinical Endocrinology, 55(1), 77-86.
Lange, M. W., Thulesen, J., Feldt-Rasmussen, U., Skakkebaek, N. E., Vahl, N., Jørgensen, J. O., ... Juul, A. (2001). Skin morphological changes in growth hormone deficiency and acromegaly. European Journal of Endocrinology, 145(2), 147-53.
Juul, A. (2001). The effects of oestrogens on linear bone growth. Human Reproduction Update, 7(3), 303-13.
Fisker, S., Nørrelund, H., Juul, A., Skakkebaek, N. E., Christiansen, J. S., & Jørgensen, J. O. (2001). The growth hormone (GH)-insulin-like growth factor axis during testosterone replacement therapy in GH-treated hypopituitary males. Growth Hormone & IGF Research, 11(2), 104-9. https://doi.org/10.1054/ghir.2001.0195
Sneppen, S. B., Lange, M. W., Pedersen, L. M., Kristensen, L. Ø., Main, K. M., Juul, A., ... Feldt-Rasmussen, U. (2001). Total and free insulin-like growth factor I, insulin-like growth factor binding protein 3 and acid-labile subunit reflect clinical activity in acromegaly. Growth Hormone & IGF Research, 11(6), 384-91. https://doi.org/10.1054/ghir.2001.0254
Nørrelund, H., Vahl, N., Juul, A., Møller, N., Alberti, K. G., Skakkebaek, N. E., ... Jørgensen, J. O. (2000). Continuation of growth hormone (GH) therapy in GH-deficient patients during transition from childhood to adulthood: impact on insulin sensitivity and substrate metabolism. Journal of Clinical Endocrinology and Metabolism, 85(5), 1912-7.
Lange, K. H., Isaksson, F., Juul, A., Rasmussen, M. H., Bülow, J., & Kjaer, M. (2000). Growth hormone enhances effects of endurance training on oxidative muscle metabolism in elderly women. American Journal of Physiology: Endocrinology and Metabolism, 279(5), E989-96.
Müller, J., Juul, A., Andersson, A. M., Sehested, A. M., & Skakkebaek, N. E. (2000). Hormonal changes during GnRH analogue therapy in children with central precocious puberty. Journal of Pediatric Endocrinology & Metabolism, 13 Suppl 1, 739-46.
Sehested, A. M., Juul, A., Andersson, A. M., Petersen, J. H., Jensen, T. K., Müller, J., & Skakkebaek, N. E. (2000). Serum inhibin A and inhibin B in healthy prepubertal, pubertal, and adolescent girls and adult women: relation to age, stage of puberty, menstrual cycle, follicle-stimulating hormone, luteinizing hormone, and estradiol levels. Journal of Clinical Endocrinology and Metabolism, 85(4), 1634-40.
Juul, A., Fisker, S., Scheike, T. H., Hertel, T. K., Müller, J., Orskov, H., & Skakkebaek, N. E. (2000). Serum levels of growth hormone binding protein in children with normal and precocious puberty: relation to age, gender, body composition and gonadal steroids. Clinical Endocrinology, 52(2), 165-72.
Sneppen, S. B., Main, K. M., Juul, A., Pedersen, L. M., Kristensen, L. O., Skakkebaek, N. E., & Feldt-Rasmussen, U. (2000). Sweat secretion rates in growth hormone disorders. Clinical Endocrinology, 53(5), 601-8.
Møller, S., Juul, A., Becker, U., & Henriksen, J. H. (2000). The acid-labile subunit of the ternary insulin-like growth factor complex in cirrhosis: relation to liver dysfunction. Journal of Hepatology, 32(3), 441-6.
Yu, H., Mistry, J., Nicar, M. J., Khosravi, M. J., Diamandis, A., van Doorn, J., & Juul, A. (1999). Insulin-like growth factors (IGF-I, free IGF-I and IGF-II) and insulin-like growth factor binding proteins (IGFBP-2, IGFBP-3, IGFBP-6, and ALS) in blood circulation. Journal of Clinical Laboratory Analysis, 13(4), 166-72.
Lund, A. M., Hansen, M., Kollerup, G. B., Juul, A., Teisner, B., & Skovby, F. (1998). Collagen-derived markers of bone metabolism in osteogenesis imperfecta. Acta paediatrica, 87(11), 1131-7.
Juul, A., Andersson, A. M., Pedersen, S. A., Jørgensen, J. O., Christiansen, J. S., Groome, N. P., & Skakkebaek, N. E. (1998). Effects of growth hormone replacement therapy on IGF-related parameters and on the pituitary-gonadal axis in GH-deficient males. A double-blind, placebo-controlled crossover study. Hormone Research, 49(6), 269-78.
Kiess, W., Anil, M., Blum, W. F., Englaro, P., Juul, A., Attanasio, A., ... Rascher, W. (1998). Serum leptin levels in children and adolescents with insulin-dependent diabetes mellitus in relation to metabolic control and body mass index. European Journal of Endocrinology, 138(5), 501-9.
Juul, A., Møller, S., Mosfeldt-Laursen, E., Rasmussen, M. H., Scheike, T. H., Pedersen, S. A., ... Skakkebaek, N. E. (1998). The acid-labile subunit of human ternary insulin-like growth factor binding protein complex in serum: hepatosplanchnic release, diurnal variation, circulating concentrations in healthy subjects, and diagnostic use in patients with growth hormone deficiency. Journal of Clinical Endocrinology and Metabolism, 83(12), 4408-15.
Juul, A., Scheike, T. H., Pedersen, A. T., Main, K. M., Andersson, A. M., Pedersen, L. M., & Skakkebaek, N. E. (1997). Changes in serum concentrations of growth hormone, insulin, insulin-like growth factor and insulin-like growth factor-binding proteins 1 and 3 and urinary growth hormone excretion during the menstrual cycle. Human Reproduction, 12(10), 2123-8.
EMALD-gruppen (1997). Den prognostiske værdi af insulinlignende vækstfaktor i (IGF-I) og bindingsproteinet IGFBP-3 ved alkoholistisk leversygdom. Ugeskrift for læger, 159(30), 4636-4640.
Kondrup, J., Nielsen, K., & Juul, A. (1997). Effect of long-term refeeding on protein metabolism in patients with cirrhosis of the liver. British Journal of Nutrition, 77(2), 197-212.
Juul, A., Holm, K., Kastrup, K. W., Pedersen, S. A., Michaelsen, K. F., Scheike, T. H., ... Skakkebaek, N. E. (1997). Free insulin-like growth factor I serum levels in 1430 healthy children and adults, and its diagnostic value in patients suspected of growth hormone deficiency. Journal of Clinical Endocrinology and Metabolism, 82(8), 2497-502.
Juul, A., Kastrup, K. W., Pedersen, S. A., & Skakkebaek, N. E. (1997). Growth hormone (GH) provocative retesting of 108 young adults with childhood-onset GH deficiency and the diagnostic value of insulin-like growth factor I (IGF-I) and IGF-binding protein-3. Journal of Clinical Endocrinology and Metabolism, 82(4), 1195-201.
Wolthers, O. D., Hansen, M., Juul, A., Nielsen, H. K., & Pedersen, S. (1997). Knemometry, urine cortisol excretion, and measures of the insulin-like growth factor axis and collagen turnover in children treated with inhaled glucocorticosteroids. Pediatric Research, 41(1), 44-50. https://doi.org/10.1203/00006450-199704001-00272
Hebebrand, J., Blum, W. F., Barth, N., Coners, H., Englaro, P., Juul, A., ... Remschmidt, H. (1997). Leptin levels in patients with anorexia nervosa are reduced in the acute stage and elevated upon short-term weight restoration. Molecular Psychiatry, 2(4), 330-4.
Blum, W. F., Englaro, P., Hanitsch, S., Juul, A., Hertel, N., Müller, J., ... Rascher, W. (1997). Plasma leptin levels in healthy children and adolescents: dependence on body mass index, body fat mass, gender, pubertal stage, and testosterone. Journal of Clinical Endocrinology and Metabolism, 82(9), 2904-10.
Juul, A., & Skakkebaek, N. E. (1997). Prediction of the outcome of growth hormone provocative testing in short children by measurement of serum levels of insulin-like growth factor I and insulin-like growth factor binding protein 3. Journal of Pediatrics, 130(2), 197-204.
Juul, A., Müller, J., & Skakkebaek, N. E. (1997). Prostate specific antigen in boys with precocious puberty before and during gonadal suppression by GnRH agonist treatment. European Journal of Endocrinology, 136(4), 401-5.
Andersson, A. M., Juul, A., Petersen, J. H., Müller, J., Groome, N. P., & Skakkebaek, N. E. (1997). Serum inhibin B in healthy pubertal and adolescent boys: relation to age, stage of puberty, and follicle-stimulating hormone, luteinizing hormone, testosterone, and estradiol levels. Journal of Clinical Endocrinology and Metabolism, 82(12), 3976-81.
Larsen, T., Main, K., Andersson, A. M., Juul, A., Greisen, G., & Skakkebaek, N. E. (1996). Growth hormone, insulin-like growth factor I and its binding proteins 1 and 3 in last trimester intrauterine growth retardation with increased pulsatility index in the umbilical artery. Clinical Endocrinology, 45(3), 315-9.
Demir, A., Voutilainen, R., Juul, A., Dunkel, L., Alfthan, H., Skakkebaek, N. E., & Stenman, U. H. (1996). Increase in first morning voided urinary luteinizing hormone levels precedes the physical onset of puberty. Journal of Clinical Endocrinology and Metabolism, 81(8), 2963-7.
Mosfeldt-Laursen, EM., Juul, A., Lanng, S., Højby, N., Koch, C., Müller, J., & Skakkebæk, N. E. (1996). Nedsatte serum koncentrationer af insulin-like growth factor hos patienter med cystisk fibrose. Ugeskrift for læger, 158(38), 5300-5302.
Møller, S., Becker, P. U., Juul, A., Skakkebaek, N. E., & Christensen, E. (1996). Prognostic value of insulinlike growth factor I and its binding protein in patients with alcohol-induced liver disease. EMALD group. Hepatology, 23(5), 1073-1078.
Juul, A., Flyvbjerg, A., Frystyk, J., Müller, J., & Skakkebaek, N. E. (1996). Serum concentrations of free and total insulin-like growth factor-I, IGF binding proteins -1 and -3 and IGFBP-3 protease activity in boys with normal or precocious puberty. Clinical Endocrinology, 44(5), 515-23.
Hertel, N. T., Scheike, T., Juul, A., Main, K. M., Holm, K., Bach-Mortensen, N., ... Müller, J. R. (1995). Kropsproportioner hos danske børn. Kurver for siddehøjde, siddehøjderatio, subiskial benloengde og armspoend. Ugeskrift for Laeger, 157(49), 6876-81.
Møller, S., Juul, A., Becker, U., Flyvbjerg, A., Skakkebaek, N. E., & Henriksen, J. H. (1995). Concentrations, release, and disposal of insulin-like growth factor (IGF)-binding proteins (IGFBP), IGF-I, and growth hormone in different vascular beds in patients with cirrhosis. The Journal of clinical endocrinology and metabolism, 80(4), 1148-1157.
Laursen, E., Juul, A., Lanng, S., Høiby, N., Koch, C., Müller, J., & Skakkebaek, N. E. (1995). Diminished concentrations of insulin-like growth factor I in cystic fibrosis. Archives of Disease in Childhood. Education and Practice Edition, 72(6), 494-7.
Juul, A., Hjortskov, N., Jepsen, L., Nielsen, B., Halkjaer-Kristensen, J., Vahl, N., ... Skakkebaek, N. E. (1995). Growth hormone deficiency and hyperthermia during exercise: a controlled study of sixteen GH-deficient patients. Journal of Clinical Endocrinology and Metabolism, 80(11), 3335-40.
Müller, J., Starup, J., Christiansen, J. S., Jørgensen, J. O., Juul, A., & Skakkebaek, N. E. (1995). Growth hormone treatment during pregnancy in a growth hormone-deficient woman. European Journal of Endocrinology, 132(6), 727-9.
Rasmussen, M. H., Juul, A., Kjems, L. L., Skakkebaek, N. E., & Hilsted, J. (1995). Lack of stimulation of 24-hour growth hormone release by hypocaloric diet in obesity. The Journal of clinical endocrinology and metabolism, 80(3), 796-801.
Rasmussen, M. H., Hvidberg, A., Juul, A., Main, K. M., Gotfredsen, A., Skakkebaek, N. E., ... Skakkebae, N. E. (1995). Massive weight loss restores 24-hour growth hormone release profiles and serum insulin-like growth factor-I levels in obese subjects. The Journal of clinical endocrinology and metabolism, 80(4), 1407-1415.
Hjortskov, N., Jepsen, L., Nielsen, B., Juul, A., & Skakkebaek, N. E. (1995). Pilocarpine iontophoresis test: an index of physiological sweat secretion? Clinical physiology (Oxford, England), 15(4), 409-14.
Juul, A., Scheike, T. H., Nielsen, C. T., Krabbe, S., Müller, J., & Skakkebaek, N. E. (1995). Serum insulin-like growth factor I (IGF-I) and IGF-binding protein 3 levels are increased in central precocious puberty: effects of two different treatment regimens with gonadotropin-releasing hormone agonists, without or in combination with an antiandrogen (cyproterone acetate). Journal of Clinical Endocrinology and Metabolism, 80(10), 3059-67.
Juul, A., Dalgaard, P., Blum, W. F., Bang, P., Hall, K. P., Michaelsen, K. F., ... Skakkebaek, N. E. (1995). Serum levels of insulin-like growth factor (IGF)-binding protein-3 (IGFBP-3) in healthy infants, children, and adolescents: the relation to IGF-I, IGF-II, IGFBP-1, IGFBP-2, age, sex, body mass index, and pubertal maturation. Journal of Clinical Endocrinology and Metabolism, 80(8), 2534-42.
Pedersen, J. F., Juul, A., Mølsted-Pedersen, L., & Skakkebaek, N. E. (1995). Serum levels of insulin-like growth factor-1 in first trimester of diabetic pregnancy: relation to early growth delay. B J O G, 102(11), 927-8.
Wolthers, O. D., Juul, A., Hansen, M., Müller, J., & Pedersen, S. (1995). The insulin-like growth factor axis and collagen turnover in asthmatic children treated with inhaled budesonide. Acta paediatrica, 84(4), 393-7.
Nielsen, K., Kondrup, J., Elsner, P., Juul, A., & Jensen, E. S. (1994). Casein and soya-bean protein have different effects on whole body protein turnover at the same nitrogen balance. British Journal of Nutrition, 72(1), 69-81.
Juul, A., Pedersen, S. A., Sørensen, S., Winkler, K., Jørgensen, J. O., Christiansen, J. S., & Skakkebaek, N. E. (1994). Growth hormone (GH) treatment increases serum insulin-like growth factor binding protein-3, bone isoenzyme alkaline phosphatase and forearm bone mineral content in young adults with GH deficiency of childhood onset. European Journal of Endocrinology, 131(1), 41-9.
Jørgensen, JOL., Møller, J., Wolthers, T., Vahn, N., Juul, A., Skakkebæk, N. E., & Christiansen, JS. (1994). Growth hormone (GH)-deficiency in adults: clinical features and effects of GH substitution. The journal of pediatric endocrinology, 283-293.
Juul, A., Bang, P., Hertel, N., Main, K., Dalgaard, P., Jørgensen, K., ... Skakkebaek, N. E. (1994). Serum insulin-like growth factor-I in 1030 healthy children, adolescents, and adults: relation to age, sex, stage of puberty, testicular size, and body mass index. Journal of Clinical Endocrinology and Metabolism, 78(3), 744-52.
Møller, S., Becker, U., Grønbaek, M., Juul, A., Winkler, K., & Skakkebaek, N. E. (1994). Short-term effect of recombinant human growth hormone in patients with alcoholic cirrhosis. Journal of Hepatology, 21(5), 710-7.
Main, K. M., Jarden, M., Angelo, L., Dinesen, B. I., Hertel, N., Juul, A., ... Skakkebaek, N. E. (1994). The impact of gender and puberty on reference values for urinary growth hormone excretion: a study of 3 morning urine samples in 517 healthy children and adults. Journal of Clinical Endocrinology and Metabolism, 79(3), 865-71.
Wolthers, O. D., Juul, A., Hansen, M., Müller, J., & Pedersen, S. (1994). The insulin-like growth factor axis and collagen turnover during prednisolone treatment. Archives of Disease in Childhood. Education and Practice Edition, 71(5), 409-13.
Juul, A., Main, K., Blum, W. F., Lindholm, J., Ranke, M. B., & Skakkebaek, N. E. (1994). The ratio between serum levels of insulin-like growth factor (IGF)-I and the IGF binding proteins (IGFBP-1, 2 and 3) decreases with age in healthy adults and is increased in acromegalic patients. Clinical Endocrinology, 41(1), 85-93.
Blum, W. F., Horn, N., Kratzsch, J., Jørgensen, J. O., Juul, A., Teale, D., ... Ranke, M. B. (1993). Clinical studies of IGFBP-2 by radioimmunoassay. Plant Growth Regulation, 3(1), 100-4.
Juul, A., Behrenscheer, A., Tims, T., Nielsen, B., Halkjaer-Kristensen, J., & Skakkebaek, N. E. (1993). Impaired thermoregulation in adults with growth hormone deficiency during heat exposure and exercise. Clinical Endocrinology, 38(3), 237-44.
Hertel, N., Stoltenberg, M., Juul, A., Main, K. M., Müller, J., Nielsen, C. T., ... Skakkebaek, N. E. (1993). Serum concentrations of type I and III procollagen propeptides in healthy children and girls with central precocious puberty during treatment with gonadotropin-releasing hormone analog and cyproterone acetate. Journal of Clinical Endocrinology and Metabolism, 76(4), 924-7.
Juul, A., & Skakkebaek, N. E. (1991). Growth hormone deficiency and hyperthermia. Lancet, 338(8771), 887.
Nielsen, J. D., Stoltenberg, M., Siemsen, M., Juul, A., Pedersen, F., & Madsen, J. K. (1990). Anvendelse af fibrinolytika ved behandling af akut myokardieinfarkt i Danmark. En spørgeskemaundersøgelse. Ugeskrift for Laeger, 152(33), 2368-70.
Nielsen, J. D., Stoltenberg, M., Juul, A., Siemsen, M., & Christiansen, I. B. (1990). Behandling af ustabil angina pectoris. En spørgeskemaundersøgelse. Ugeskrift for Laeger, 152(33), 2372-4.
Juul, A., & Pedersen, A. T. (1990). Endogene opioider og deres terapeutiske anvendelse i smertebehandling. Ugeskrift for Laeger, 152(6), 372-5.
Siemsen, M., & Juul, A. (1990). Stavnsbåndet genindføres. Stud Med, 53(64), 11.
Juul, A., Juul, P., & Christensen, H. B. (1989). Guanethidine-induced sympathectomy in the nude rat. Pharmacol Toxicol, 64(1), 20-2.

Letters and Editorials

Damsgaard, J., Joensen, U. N., Carlsen, E., Erenpreiss, J., Jensen, M. B., Matulevicius, V., ... Jørgensen, N. (2017). Reply to Eugenio Ventimiglia, Francesco Montorsi, and Andrea Salonia's Letter to the Editor: Jakob Damsgaard, Ulla N. Joensen, Elisabeth Carlsen, et al. Varicocele Is Associated with Impaired Semen Quality and Reproductive Hormone Levels: A Study of 7035 Healthy Young Men from Six European Countries. Eur Urol 2016;70:1019-29. European Urology, 71(2), e71-e72. https://doi.org/10.1016/j.eururo.2016.09.002
Skakkebæk, N. E., Andersson, A-M., Juul, A., Jensen, T. K., Almstrup, K., Toppari, J., & Jørgensen, N. (2011). Commentary: sperm counts, data responsibility, and good scientific practice. Epidemiology, 22(5), 620-1. https://doi.org/10.1097/EDE.0b013e318229ec01
Juul, A. (2011). In utero programming of pubertal development? Archives of Disease in Childhood, 96(8), 703. https://doi.org/10.1136/adc.2010.202028
Juul, A., Main, K. M., & Skakkebæk, N. E. (2011). Disorders of sexual differentiation-the tip of the iceberg? Nature Reviews Endocrinology, 7, 504-5.
Juul, A., & Møller, S. (1997). IGF-I in cronic liver dissease: A marker of hepatocellular, malnutrition, and survival. Nutrition, 13(3), 231-232.

Book chapters and Proceedings

Juul, A., Aksglaede, L., Bay, K., Grigor, K. M., & Skakkebæk, N. E. (2011). Klinefelter syndrome: the forgotten syndrome: basic and clinical questions posed to an international group of scientists. Acta paediatrica, 100(6), 791-2. https://doi.org/10.1111/j.1651-2227.2011.02283.x
Ranke, MB., Feldt-Rasmussen, U., Bang, P., Baxter, RC., Camacho-Hübner, C., Clemmons, DR., ... Strassburger, CJ. (2001). Consensus on how to measure insulin-like growth factor-I (IGF-I). Hormone Research, 55, 106-109.
Juul, A., & Thorn, NA. (1989). Characterization of the uptake of DADLE to isolated nerve terminals - morphine stimulates uptake. Journal of Neuroendocrinology, 101-102.

ID: 30784271