False-positive findings in Cochrane meta-analyses with and without application of trial sequential analysis: an empirical review

Imberger, G., Thorlund, K., Gluud, C. & Wetterslev, J., 2016, I : B M J Open. 6, 8, s. e011890

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FibroTest, transient elastography method, and combined FibroTest and transient elastography method for diagnosis of severe hepatic fibrosis and cirrhosis in adults with chronic hepatitis C (Protocol)

Pavlov, C. S., Casazza, G., Nikolova, D. K., Tsochatzis, E. A., Ivashkin, V. T. & Gluud, C., 2016, I : Cochrane Database of Systematic Reviews. 7, s. CD012291

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Glucocorticosteroids for people with alcoholic hepatitis (Protocol)

Pavlov, C. S., Tsochatzis, E. A., Casazza, G., Nikolova, D. K., Volcek, E. & Gluud, C., 2016, I : Cochrane Database of Systematic Reviews. 6, s. CD001511

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Inhaled nitric oxide for acute respiratory distress syndrome (ARDS) in children and adults

Gebistorf, F., Karam, O., Wetterslev, J. & Afshari, A., 2016, I : Cochrane Database of Systematic Reviews. 6, s. CD002787

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Is heat pain detection threshold associated with the area of secondary hyperalgesia following brief thermal sensitization? A study of healthy volunteers - design and detailed plan of analysis

Hansen, M. S., Wetterslev, J., Pipper, C. B., Asghar, M. S. & Dahl, J. B., 2016, I : B M C Anesthesiology. 16, 1, s. 28

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Is the Volume of the Caudate Nuclei Associated With Area of Secondary Hyperalgesia? - Protocol for a 3-Tesla MRI Study of Healthy Volunteers

Hansen, M. S., Asghar, M. S., Wetterslev, J., Pipper, C. B., Johan Mårtensson, J., Becerra, L., Christensen, A., Nybing, J. D., Havsteen, I., Boesen, M. & Dahl, J. B., 2016, I : JMIR research protocols. 5, 2, s. e117

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Markers of endothelial damage and coagulation impairment in patients with severe sepsis resuscitated with hydroxyethyl starch 130/0.42 vs Ringer acetate

Müller, R., Ostrowski, S. R., Haase, N., Wetterslev, J., Perner, A. & Johansson, P. I., 2016, I : Journal of Critical Care. 32, s. 16-20

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Metformin versus placebo in combination with insulin analogues in patients with type 2 diabetes mellitus-the randomised, blinded Copenhagen Insulin and Metformin Therapy (CIMT) trial

Lundby-Christensen, L., Tarnow, L., Boesgaard, T. W., S Lund, S., Wiinberg, N., Perrild, H., Krarup, T., Snorgaard, O., Gade-Rasmussen, B., Thorsteinsson, B., Røder, M., Mathiesen, E. R., Jensen, T., Vestergaard, H., Hedetoft, C., Breum, L., Duun, E., Sneppen, S. E. B., Pedersen, O., Hemmingsen, B., Carstensen, B., Madsbad, S., Gluud, C., Wetterslev, J., Vaag, A. & Almdal, T. P., 2016, I : B M J Open. 6, 2, s. e008376

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Methylphenidate for attention deficit hyperactivity disorder (ADHD) in children and adolescents - assessment of harmful effects in non-randomised studies (Protocol)

Storebø, O. J., Pedersen, N., Ramstad, E., Krogh, H., Moreira-Maia, C. R., Magnusson, F. L., Holmskov, M., Nilausen, T. D., Skoog, M., Rosendal, S., Groth, C., Gillies, D., Rasmussen, K. B., Gauci, D., Zwi, M., Kirubakaran, R., Forsbøl, B., Håkonsen, S. J., Aagaard, L., Simonsen, E. & Gluud, C., 2016, I : Cochrane Database of Systematic Reviews. 2, s. CD012069

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Modified intention-to-treat analysis did not bias trial results

Dossing, A., Tarp, S., Furst, D. E., Gluud, C., Wells, G. A., Beyene, J., Hansen, B. B., Bliddal, H. & Christensen, R., 2016, I : Journal of Clinical Epidemiology. 72, s. 66-74

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No effect of escitalopram versus placebo on brain-derived neurotrophic factor in healthy individuals: a randomised trial

Knorr, U., Koefoed, P., Soendergaard, M. H. G., Vinberg, M., Gether, U., Gluud, C., Wetterslev, J., Winkel, P. & Kessing, L. V., 2016, I : Acta Neuropsychiatrica. 2, s. 101-9 9 s.

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Non-acute percutaneous coronary intervention versus medical therapy in patients with ischaemic heart disease (Protocol)

Nielsen, E. E., Feinberg, J., Wetterslev, J., Gluud, C. & Jakobsen, J. C., 2016, I : Cochrane Database of Systematic Reviews. 1, s. CD012068

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Non-invasive positive pressure ventilation for acute asthma in children (Protocol)

Korang, SK., Feinberg, J., Wetterslev, J. & Jakobsen, J. C., 2016, I : Cochrane Database of Systematic Reviews. 1, s. CD012067

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Predictive value of interleukin-6 in post-cardiac arrest patients treated with targeted temperature management at 33°C or 36°C

Bro-Jeppesen, J., Kjaergaard, J., Stammet, P., Wise, M. P., Hovdenes, J., Åneman, A., Horn, J., Devaux, Y., Erlinge, D., Gasche, Y., Wanscher, M., Cronberg, T., Friberg, H., Wetterslev, J., Pellis, T., Kuiper, M., Nielsen, N., Hassager, C. & TTM-trial investigators, 2016, I : Resuscitation. 98, s. 1-8 8 s.

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Prolonged-release melatonin versus placebo for benzodiazepine discontinuation in patients with schizophrenia or bipolar disorder: A randomised, placebo-controlled, blinded trial

Baandrup, L., Lindschou, J., Winkel, P., Gluud, C. & Glenthøj, B. Y., 2016, I : The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. 17, s. 514-524 11 s.

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Pulmonary artery perfusion versus no pulmonary perfusion during cardiopulmonary bypass in patients with COPD: a randomised clinical trial

Buggeskov, K. B., Sundskard, M. M., Jonassen, T., Andersen, L. W., Secher, N. H., Ravn, H. B., Steinbrüchel, D. A., Jakobsen, J. C. & Wetterslev, J., 2016, I : BMJ Open Respiratory Research. 3, 1, s. e000146

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Stress ulcer prophylaxis in adult neurocritical care patients-no firm evidence for benefit or harm

Krag, M., Perner, A., Wetterslev, J. & Møller, M. H., 2016, I : Critical care (London, England). 20, 1, s. 22

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Stress ulcer prophylaxis with a proton pump inhibitor versus placebo in critically ill patients (SUP-ICU trial): study protocol for a randomised controlled trial

Krag, M., Perner, A., Wetterslev, J., Wise, M. P., Borthwick, M., Bendel, S., Pelosi, P., Keus, F., Guttormsen, A. B., Schefold, J. C., Møller, M. H. & SUP-ICU investigators, 2016, I : Trials. 17, 1, s. 205

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The Area of Secondary Hyperalgesia following Heat Stimulation in Healthy Male Volunteers: Inter- and Intra-Individual Variance and Reproducibility

Hansen, M. S., Wetterslev, J., Pipper, C. B., Østervig, R., Asghar, M. S. & Dahl, J. B., 2016, I : P L o S One. 11, 5, s. e0155284

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The SafeBoosC II randomised trial: treatment guided by near-infrared spectroscopy reduces cerebral hypoxia without changing early biomarkers of brain injury

Plomgaard, A. M., van Oeveren, W., Hvass Petersen, T., Alderliesten, T., Austin, T., van Bel, F., Benders, M., Claris, O., Dempsey, E., Franz, A., Fumagalli, M., Gluud, C., Hagmann, C., Hyttel-Sørensen, S., Lemmers, P., Pellicer, A., Pichler, G., Winkel, P. & Greisen, G., 2016, I : Pediatric Research. 79, 4, s. 528-35

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The SafeBoosC phase II clinical trial: an analysis of the interventions related with the oximeter readings

Riera, J., Hyttel-Sorensen, S., Bravo, M. C., Cabañas, F., López-Ortego, P., Sanchez, L., Ybarra, M., Dempsey, E., Greisen, G., Austin, T., Claris, O., Fumagalli, M., Gluud, C., Lemmers, P., Pichler, G., Plomgaard, A. M., van Bel, F., Wolf, M. & Pellicer, A., 2016, I : Archives of Disease in Childhood. Fetal and Neonatal Edition. 101, s. F333-F338

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Thrombolysis for acute upper extremity deep vein thrombosis (Protocol)

Feinberg, J., Nielsen, E. E. & Jakobsen, J. C., 2016, I : Cochrane Database of Systematic Reviews. 4, s. CD012175

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Time to start of cardiopulmonary resuscitation and the effect of target temperature management at 33°C and 36°C

Dankiewicz, J., Friberg, H., Bělohlávek, J., Walden, A., Hassager, C., Cronberg, T., Erlinge, D., Gasche, Y., Hovdenes, J., Horn, J., Kjaergaard, J., Kuiper, M., Pellis, T., Stammet, P., Wanscher, M., Wetterslev, J., Wise, M., Åneman, A. & Nielsen, N., 2016, I : Resuscitation. 99, s. 44-49

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Systematic reviews of anesthesiologic interventions reported as statistically significant: problems with power, precision, and type 1 error protection

Imberger, G., Gluud, C., Boylan, J. & Wetterslev, J., dec. 2015, I : Anesthesia and Analgesia. 121, 6, s. 1611-22 12 s.

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WITHDRAWN: S-adenosyl-L-methionine for alcoholic liver diseases

Rambaldi, A. & Gluud, C., 11 nov. 2015, I : Cochrane Database of Systematic Reviews. 11, s. CD002235

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Cavity lining after excavating caries lesions: meta-analysis and trial sequential analysis of randomized clinical trials

Schwendicke, F., Göstemeyer, G. & Gluud, C., 8 aug. 2015, I : Journal of Dentistry. 43, 11, s. 1291-7

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Variability in targeted arterial oxygenation levels in patients with severe sepsis or septic shock

Dahl, R. M., Grønlykke, L., Haase, N., Holst, L. B., Perner, A., Wetterslev, J., Rasmussen, B. S., Meyhoff, C. S. & 6S-Trial and TRISS Trial investigators, aug. 2015, I : Acta Anaesthesiologica Scandinavica. 59, 7, s. 859-69 11 s.

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Risk Factors for and Prediction of a Difficult Neuraxial Block: A Cohort Study of 73,579 Patients from the Danish Anaesthesia Database

Stendell, L., Lundstrøm, L. H., Wetterslev, J., Itenov, T. S. & Rosenstock, C. V., 31 jul. 2015, I : Regional Anesthesia and Pain Medicine. 40, 5, s. 545-552

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WITHDRAWN: Targeting intensive glycaemic control versus targeting conventional glycaemic control for type 2 diabetes mellitus

Hemmingsen, B., Lund, S. S., Gluud, C., Vaag, A., Almdal, T. P. & Wetterslev, J., 29 jul. 2015, I : Cochrane Database of Systematic Reviews. 7, s. CD008143

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Lower urinary tract symptoms after subtotal versus total abdominal hysterectomy: exploratory analyses from a randomized clinical trial with a 14-year follow-up

Andersen, L. L., Møller, L. M. A., Gimbel, H. & Danish Hysterectomy Trial Group, 28 jul. 2015, I : International Urogynecology Journal. 261, s. 1767-1772

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No difference in mortality between men and women after out-of-hospital cardiac arrest

Winther-Jensen, M., Kjaergaard, J., Wanscher, M., Nielsen, N., Wetterslev, J., Cronberg, T., Erlinge, D., Friberg, H., Gasche, Y., Horn, J., Hovdenes, J., Kuiper, M., Pellis, T., Stammet, P., Wise, M. P., Åneman, A. & Hassager, C., 26 jul. 2015, I : Resuscitation. 96, s. 78-84 12 s.

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Impact of time to return of spontaneous circulation on neuroprotective effect of targeted temperature management at 33 or 36 degrees in comatose survivors of out-of hospital cardiac arrest

Kjaergaard, J., Nielsen, N., Winther-Jensen, M., Wanscher, M., Pellis, T., Kuiper, I., Thomsen, J. H., Wetterslev, J., Cronberg, T., Bro-Jeppesen, J., Erlinge, D., Friberg, H., Søholm, H., Gasche, Y., Horn, J., Hovdenes, J., Stammet, P., Wise, M. P., Åneman, A. & Hassager, C., 7 jul. 2015, I : Resuscitation. 96, s. 310-316

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Prothrombin complex concentrate for reversal of vitamin K antagonist treatment in bleeding and non-bleeding patients

Johansen, M., Wikkelsø, A., Lunde, J., Wetterslev, J. & Afshari, A., 7 jul. 2015, I : Cochrane Database of Systematic Reviews. 7, s. CD010555

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Glucocorticosteroids for sepsis: systematic review with meta-analysis and trial sequential analysis

Volbeda, M., Wetterslev, J., Gluud, C., Zijlstra, J. G., van der Horst, I. C. C. & Keus, F., jul. 2015, I : Intensive Care Medicine. 41, 7, s. 1220-34 15 s.

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Individual placement and support supplemented with cognitive remediation and work-related social skills training in Denmark: study protocol for a randomized controlled trial

Christensen, T. N., Nielsen, I. G., Stenager, E., Morthorst, B. R., Lindschou, J., Nordentoft, M. & Eplov, L. F., 21 jun. 2015, I : Trials. 16, 1, s. 280

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Trials on stress ulcer prophylaxis: finding the balance between benefit and harm

Krag, M., Perner, A., Wetterslev, J., Wise, M. P. & Møller, M. H., 3 jun. 2015, I : Intensive Care Medicine. 41, 7, s. 1367-8

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Protocol for CHANGE: a randomized clinical trial assessing lifestyle coaching plus care coordination versus care coordination alone versus treatment as usual to reduce risks of cardiovascular disease in adults with schizophrenia and abdominal obesity

Speyer, H., Nørgaard, H. C. B., Hjorthøj, C., Madsen, T. A., Drivsholm, S., Pisinger, C., Gluud, C., Mors, O., Krogh, J. & Nordentoft, M., 23 maj 2015, I : B M C Psychiatry. 15, 1, s. 119

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Neuron-Specific Enolase as a Predictor of Death or Poor Neurological Outcome After Out-of-Hospital Cardiac Arrest and Targeted Temperature Management at 33°C and 36°C

Stammet, P., Collignon, O., Hassager, C., Wise, M. P., Hovdenes, J., Åneman, A., Horn, J., Devaux, Y., Erlinge, D., Kjaergaard, J., Gasche, Y., Wanscher, M., Cronberg, T., Friberg, H., Wetterslev, J., Pellis, T., Kuiper, M., Gilson, G., Nielsen, N. & TTM-Trial Investigators, 19 maj 2015, I : Journal of the American College of Cardiology. 65, 19, s. 2104-14 11 s.

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Vitamin D, carotid intima-media thickness, and bone structure in patients with type 2 diabetes

Winckler, K., Tarnow, L., Christensen, L. L., Almdal, T. P., Wiinberg, N., Eiken, P., Boesgaard, T. W. & CIMT trial group (Bianca Hemmingsen, member), 8 maj 2015, I : Endocrine Connections. 4, 2, s. 128-135

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Stress ulcer prophylaxis in the intensive care unit: an international survey of 97 units in 11 countries

Krag, M., Perner, A., Wetterslev, J., Wise, M. P., Borthwick, M., Bendel, S., McArthur, C., Cook, D., Nielsen, N., Pelosi, P., Keus, F., Guttormsen, A. B., Moller, A. D., Møller, M. H. & SUP-ICU Collaborators, maj 2015, I : Acta Anaesthesiologica Scandinavica. 59, 5, s. 576-85 10 s.

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Neurological prognostication after cardiac arrest and targeted temperature management 33°C versus 36°C: Results from a randomised controlled clinical trial

Dragancea, I., Horn, J., Kuiper, M., Friberg, H., Ullén, S., Wetterslev, J., Cranshaw, J., Hassager, C., Nielsen, N., Cronberg, T. & TTM trial investigators, 25 apr. 2015, I : Resuscitation. 93, s. 164-170

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Prevalence and outcome of gastrointestinal bleeding and use of acid suppressants in acutely ill adult intensive care patients

Krag, M., Perner, A., Wetterslev, J., Wise, M. P., Borthwick, M., Bendel, S., McArthur, C., Cook, D., Nielsen, N., Pelosi, P., Keus, F., Guttormsen, A. B., Moller, A. D., Møller, M. H., SUP-ICU co-authors & Bestle, M. (red.), 10 apr. 2015, I : Intensive Care Medicine. 41, 5, s. 833-45

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Testing current practice is no mistake

Perner, A., Haase, N., Wetterslev, J. & Holst, L. B., 8 apr. 2015, I : Intensive Care Medicine. 41, 5, s. 960

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Neurologic function and health-related quality of life in patients following targeted temperature management at 33°C vs 36°C after out-of-hospital cardiac arrest: A Randomized Clinical Trial

Cronberg, T., Lilja, G., Horn, J., Kjaergaard, J., Wise, M. P., Pellis, T., Hovdenes, J., Gasche, Y., Åneman, A., Stammet, P., Erlinge, D., Friberg, H., Hassager, C., Kuiper, M., Wanscher, M., Bosch, F., Cranshaw, J., Kleger, G-R., Persson, S., Undén, J., Walden, A., Winkel, P., Wetterslev, J., Nielsen, N. & TTM Trial Investigators, 6 apr. 2015, I : JAMA Neurology. 72, 6, s. 634-41

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DEPERROR: Risks of systematic errors in drug and non-drug randomized clinical trials assessing intervention effects in patients with unipolar depression

Krogh, J., Hjorthøj, C. R., Jakobsen, J. C., Lindschou, J., Kessing, L. V., Nordentoft, M. & Gluud, C., 1 apr. 2015, I : Journal of Affective Disorders. 179, s. 121-127 7 s.

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Complete versus culprit-only revascularization for ST-segment-elevation myocardial infarction and multivessel disease: a Meta-analysis and Trial Sequential Analysis of randomized trials

Bangalore, S., Toklu, B. & Wetterslev, J., apr. 2015, I : Circulation. Cardiovascular interventions. 8, 4, s. pii:e002142

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