Higher versus lower fraction of inspired oxygen or targets of arterial oxygenation for adults admitted to the intensive care unit

Barbateskovic, M., Schjørring, O. L., Russo Krauss, S., Jakobsen, J. C., Meyhoff, C. S., Dahl, R. M., Rasmussen, B. S., Perner, A. & Wetterslev, J., 27 nov. 2019, I : Cochrane Database of Systematic Reviews. 2019, 11, s. CD012631 CD012631.

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Low Dose Low-Molecular-Weight Heparin for Thrombosis Prophylaxis: Systematic Review with Meta-Analysis and Trial Sequential Analysis

Eck, R. J., Bult, W., Wetterslev, J., Gans, R. O. B., Meijer, K., van der Horst, I. C. C. & Keus, F., 21 nov. 2019, I : Journal of Clinical Medicine. 8, 12, s. pii:E2039

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Xiao Chai Hu Tang, a herbal medicine, for chronic hepatitis B

Kong, D. Z., Liang, N., Yang, G. L., Zhang, Z., Liu, Y., Li, J., Liu, X., Liang, S., Nikolova, D., Jakobsen, J. C., Gluud, C. & Liu, J., 7 nov. 2019, I : Cochrane Database of Systematic Reviews. 2019, 11

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Fever control interventions versus placebo, sham or no intervention in adults: a protocol for a systematic review with meta-analysis and Trial Sequential Analysis

Sethi, N., Naqash, A. I., Nielsen, N. & Jakobsen, J. C., 3 nov. 2019, I : BMJ Open. 9, 11, s. e032389

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Lifestyle Interventions for Weight Management in People with Serious Mental Illness: A Systematic Review with Meta-Analysis, Trial Sequential Analysis, and Meta-Regression Analysis Exploring the Mediators and Moderators of Treatment Effects

Speyer, H., Jakobsen, A. S., Westergaard, C., Nørgaard, H. C. B., Pisinger, C., Krogh, J., Hjorthøj, C., Nordentoft, M., Gluud, C., Correll, C. U. & Jørgensen, K. B., 1 nov. 2019, I : Psychotherapy and Psychosomatics. 88, 6, s. 350-362 13 s.

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Agents Intervening against Delirium in the Intensive Care Unit (AID-ICU) - Protocol for a randomised placebo-controlled trial of haloperidol in patients with delirium in the ICU

Andersen-Ranberg, N., Poulsen, L. M., Perner, A., Wetterslev, J., Estrup, S., Lange, T., Ebdrup, B., Hästbacka, J., Morgan, M. P. G., Citerio, G., Zafrani, L., Caballero, J., Collet, M. O., Weber, S., Andreasen, A. S., Bestle, M., Pedersen, H. B. S., Hildebrandt, T., Thee, C., Jensen, T. B., Dey, N., Nielsen, L. G. & Mathiesen, O., nov. 2019, I : Acta Anaesthesiologica Scandinavica. 63, 10, s. 1426-1433 8 s.

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Storage time of red blood cells among ICU patients with septic shock

Rygård, S. L., Grønlykke, L., Perner, A., Winkel, P., Lange, T., Holst, L. B., Johansson, P. I., Aneman, A., Brodersen, T., Laurén, E., Ullum, H. & Wetterslev, J., nov. 2019, I : Acta Anaesthesiologica Scandinavica. 63, 10, s. 1366-1377 12 s.

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Cannabinoids versus placebo or no intervention for pain: protocol for a systematic review with meta-analysis and trial sequential analysis

Barakji, J. A., Korang, S. K., Feinberg, J., Maagard, M., Gluud, C., Mathiesen, O. & Jakobsen, J. C., 31 okt. 2019, I : BMJ Open. 9, 10, s. e031574

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The effects of adding angiotensin receptor neprilysin inhibitors to usual care in patients with heart failure: a protocol for a systematic review of randomised clinical trials with meta-analysis and trial sequential analysis

Nielsen, E. E., Feinberg, J., Raymond, I., Olsen, M. H., Steensgaard-Hansen, F. V. & Jakobsen, J. C., 31 okt. 2019, I : Systematic Reviews. 8, 1, s. 251

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Coronary artery bypass surgery plus medical therapy versus medical therapy alone for ischaemic heart disease: a protocol for a systematic review with meta-analysis and trial sequential analysis

Lorenzen, U. S., Buggeskov, K. B., Nielsen, E. E., Sethi, N. J., Carranza, C. L., Gluud, C. & Jakobsen, J. C., 28 okt. 2019, I : Systematic Reviews. 8, 1, s. 246

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Outcomes of Prophylactic Pantoprazole in Adult Intensive Care Unit Patients Receiving Dialysis: Results of a Randomized Trial

Schefold, J. C., Krag, M., Marker, S., Perner, A., Wetterslev, J., Wise, M. P., Borthwick, M., Bendel, S., Keus, F., Guttormsen, A. B., Lange, T., the SUP-ICU investigators & Møller, M. H., 1 okt. 2019, I : American Journal of Nephrology. 50, 4, s. 312-319 8 s.

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Prompt closure versus gradual weaning of extraventricular drainage for hydrocephalus in adult patients with aneurysmal subarachnoid haemorrhage: a systematic review protocol with meta-analysis and trial sequential analysis

Capion, T., Lilja-Cyron, A., Juhler, M., Mathiesen, T. I. & Wetterslev, J., 1 okt. 2019, I : BMJ Open. 9, 10, s. e029719

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A difficulty with the DIFFMASK score is the difficult statistics - a reply

Lundstrøm, L. H., Rosenstock, C. V., Wetterslev, J. & Nørskov, A. K., okt. 2019, I : Anaesthesia. 74, 10, s. 1338 1 s.

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Conservative vs liberal fluid therapy in septic shock (CLASSIC) trial—Protocol and statistical analysis plan

Meyhoff, T. S., Hjortrup, P. B., Møller, M. H., Wetterslev, J., Lange, T., Kjaer, M-B. N., Jonsson, A. B., Hjortsø, C. J. S., Cronhjort, M., Laake, J. H., Jakob, S. M., Nalos, M., Pettilä, V., van der Horst, I., Ostermann, M., Mouncey, P., Rowan, K., Cecconi, M., Ferrer, R., Malbrain, M. L. N. G., Ahlstedt, C., Hoffmann, S., Bestle, M. H., Nebrich, L., Russell, L., Vang, M., Rasmussen, M. L., Sølling, C., Rasmussen, B. S., Brøchner, A. C. & Perner, A., okt. 2019, I : Acta Anaesthesiologica Scandinavica. 63, 9, s. 1262-1271 10 s.

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Pantoprazole in ICU patients at risk for gastrointestinal bleeding-1-year mortality in the SUP-ICU trial

Marker, S., Krag, M., Perner, A., Wetterslev, J., Lange, T., Wise, M. P., Borthwick, M., Bendel, S., Keus, F., Guttormsen, A. B., Schefold, J. C., Rasmussen, B. S., Elkmann, T., Bestle, M., Arenkiel, B., Laake, J. H., Kamper, M. K., Lång, M., Pawlowicz-Dworzanska, M. B., Karlsson, S., Liisanantti, J., Dey, N., Knudsen, H., Granholm, A., SUP-ICU trial investigators & Møller, M. H., okt. 2019, I : Acta Anaesthesiologica Scandinavica. 63, 9, s. 1184-1190 7 s.

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Selective serotonin reuptake inhibitors are still harmful and ineffective. Responses to the comments by Hieronymus et al

Kiran Kumar, K., Naqash Javaid, S., Janus Christian, J. & Christian, G., okt. 2019, I : Acta Neuropsychiatrica. 31, 5, s. 276-284 9 s.

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Effects of Individual Placement and Support Supplemented With Cognitive Remediation and Work-Focused Social Skills Training for People With Severe Mental Illness: A Randomized Clinical Trial

Christensen, T. N., Wallstrøm, I. G., Stenager, E., Bojesen, A. B., Gluud, C., Nordentoft, M. & Eplov, L. F., 4 sep. 2019, I : JAMA Psychiatry. 76, 12, s. 1232-1240 9 s.

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Therapeutic hypothermia for acute ischaemic stroke. Results of a European multicentre, randomised, phase III clinical trial

EuroHYP-1 investigators, sep. 2019, I : European Stroke Journal. 4, 3, s. 254-262 9 s.

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Time to onset of gastrointestinal bleeding in the SUP-ICU trial: a preplanned substudy

Granholm, A., Lange, T., Anthon, C. T., Marker, S., Krag, M., Meyhoff, T. S., Wise, M. P., Borthwick, M., Bendel, S., Keus, F., Guttormsen, A. B., Schefold, J. C., Wetterslev, J., Perner, A. & Møller, M. H., 23 aug. 2019, I : Acta Anaesthesiologica Scandinavica. 63, 10, s. 1346-1356

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Acupuncture for chronic hepatitis B

Kong, D. Z., Liang, N., Yang, G. L., Zhang, Z., Liu, Y., Yang, Y., Liu, Y. X., Wang, Q. G., Zhang, F., Zhang, H. Y., Nikolova, D., Jakobsen, J. C., Gluud, C. & Liu, J., 22 aug. 2019, I : Cochrane Database of Systematic Reviews. 8, s. CD013107

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Exercise-Based Rehabilitation for Heart Failure: Cochrane Systematic Review, Meta-Analysis, and Trial Sequential Analysis

Taylor, R. S., Long, L., Mordi, I. R., Madsen, M. T., Davies, E. J., Dalal, H., Rees, K., Singh, S. J., Gluud, C. & Zwisler, A-D., 1 aug. 2019, I : JACC. Heart failure. 7, 8, s. 691-705 15 s.

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Handling Oxygenation Targets in the Intensive Care Unit (HOT-ICU)-Protocol for a randomised clinical trial comparing a lower vs a higher oxygenation target in adults with acute hypoxaemic respiratory failure

Schjørring, O. L., Perner, A., Wetterslev, J., Lange, T., Keus, F., Laake, J. H., Okkonen, M., Siegemund, M., Morgan, M., Thormar, K. M., and the HOT-ICU Investigators & Rasmussen, B. S., aug. 2019, I : Acta Anaesthesiologica Scandinavica. 63, 7, s. 956-965 10 s.

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Clinical Examination for the Prediction of Mortality in the Critically Ill: The Simple Intensive Care Studies-I

Hiemstra, B., Eck, R. J., Wiersema, R., Kaufmann, T., Koster, G., Scheeren, T. W. L., Snieder, H., Perner, A., Pettilä, V., Wetterslev, J., Keus, F. & van der Horst, I. C. C., 25 jul. 2019, I : Critical Care Medicine. 47, 10, s. 1301-1309

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Heterogeneity of treatment effect of stress ulcer prophylaxis in ICU patients: A secondary analysis protocol

Granholm, A., Marker, S., Krag, M., Zampieri, F. G., Thorsen-Meyer, H-C., Kaas-Hansen, B. S., van der Horst, I. C. C., Lange, T., Wetterslev, J., Perner, A. & Møller, M. H., 18 jul. 2019, I : Acta Anaesthesiologica Scandinavica. 63, 9, s. 1251-1256

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Short-term versus long-term psychotherapy for adult psychiatric disorders: a protocol for a systematic review with meta-analysis and trial sequential analysis

Juul, S., Poulsen, S., Lunn, S., Sørensen, P., Jakobsen, J. C. & Simonsen, S., 13 jul. 2019, I : Systematic Reviews. 8, 1, s. 169

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Total serum bile acids or serum bile acid profile, or both, for the diagnosis of intrahepatic cholestasis of pregnancy

Manzotti, C., Casazza, G., Stimac, T., Nikolova, D. & Gluud, C., 5 jul. 2019, I : Cochrane Database of Systematic Reviews. 7, s. CD012546

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Plasma expanders for people with cirrhosis and large ascites treated with abdominal paracentesis

Simonetti, R. G., Perricone, G., Nikolova, D., Bjelakovic, G. & Gluud, C., 28 jun. 2019, I : Cochrane Database of Systematic Reviews. 6, s. CD004039

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Quinolones for sepsis. A protocol for a systematic review of randomised clinical trials with meta-analysis and trial sequential analysis

Korang, S. K., Maagaard, M., Feinberg, J., Perner, A., Gluud, C. & Jakobsen, J. C., 28 jun. 2019, I : Acta Anaesthesiologica Scandinavica. 63, 8, s. 1113-1123

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Targeted hypothermia versus targeted Normothermia after out-of-hospital cardiac arrest (TTM2): A randomized clinical trial-Rationale and design

Dankiewicz, J., Cronberg, T., Lilja, G., Jakobsen, J. C., Bělohlávek, J., Callaway, C., Cariou, A., Eastwood, G., Erlinge, D., Hovdenes, J., Joannidis, M., Kirkegaard, H., Kuiper, M., Levin, H., Morgan, M. P. G., Nichol, A. D., Nordberg, P., Oddo, M., Pelosi, P., Rylander, C., Saxena, M., Storm, C., Taccone, F., Ullén, S., Wise, M. P., Young, P., Friberg, H. & Nielsen, N., 26 jun. 2019, I : American Heart Journal. 217, s. 23-31 9 s.

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Radix Sophorae flavescentis versus other drugs or herbs for chronic hepatitis B

Liang, N., Kong, D. Z., Lu, C. L., Ma, S. S., Li, Y. Q., Nikolova, D., Jakobsen, J. C., Gluud, C. & Liu, J. P., 24 jun. 2019, I : Cochrane Database of Systematic Reviews. 6, s. CD013106

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Social skills training for attention deficit hyperactivity disorder (ADHD) in children aged 5 to 18 years

Storebø, O. J., Elmose Andersen, M., Skoog, M., Joost Hansen, S., Simonsen, E., Pedersen, N., Tendal, B., Callesen, H. E., Faltinsen, E. & Gluud, C., 21 jun. 2019, I : Cochrane Database of Systematic Reviews. 6, s. CD008223

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Apparently conclusive meta-analyses on interventions in critical care may be inconclusive - a meta-epidemiological study

Koster, T. M., Wetterslev, J., Gluud, C., Jakobsen, J. C., Kaufmann, T., Eck, R. J., Koster, G., Hiemstra, B., van der Horst, I. C. C. & Keus, F., 11 jun. 2019, I : Journal of Clinical Epidemiology. 114, s. 1-10

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Power estimations for non-primary outcomes in randomised clinical trials

Jakobsen, J. C., Ovesen, C., Winkel, P., Hilden, J., Gluud, C. & Wetterslev, J., 6 jun. 2019, I : BMJ Open. 9, 6, s. e027092

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Circulating endostatin as a risk factor for cardiovascular events in patients with stable coronary heart disease: A CLARICOR trial sub-study

Ruge, T., Carlsson, A. C., Kjøller, E., Hilden, J., Kolmos, H. J., Sajadieh, A., Kastrup, J., Jensen, G. B., Larsson, A., Nowak, C., Jakobsen, J. C., Winkel, P., Gluud, C. & Ärnlöv, J., maj 2019, I : Atherosclerosis. 284, s. 202-208 7 s.

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Pantoprazole prophylaxis in ICU patients with high severity of disease: a post hoc analysis of the placebo-controlled SUP-ICU trial

Marker, S., Perner, A., Wetterslev, J., Krag, M., Lange, T., Wise, M. P., Borthwick, M., Bendel, S., Keus, F., Guttormsen, A. B., Schefold, J. C., SUP-ICU investigators & Møller, M. H., maj 2019, I : Intensive Care Medicine. 45, 5, s. 609-618 10 s.

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Glucocorticosteroids for people with alcoholic hepatitis

Pavlov, C. S., Varganova, D. L., Casazza, G., Tsochatzis, E., Nikolova, D. & Gluud, C., 9 apr. 2019, I : Cochrane Database of Systematic Reviews. 4, s. CD001511

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Short-term versus long-term mentalization-based therapy for outpatients with subthreshold or diagnosed borderline personality disorder: a protocol for a randomized clinical trial

Juul, S., Lunn, S., Poulsen, S., Sørensen, P., Salimi, M., Jakobsen, J. C., Bateman, A. & Simonsen, S., 5 apr. 2019, I : Trials. 20, 1, s. 196

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Assessing assumptions for statistical analyses in randomised clinical trials

Nielsen, E. E., Nørskov, A. K., Lange, T., Thabane, L., Wetterslev, J., Beyersmann, J., de Uña-Álvarez, J., Torri, V., Billot, L., Putter, H., Winkel, P., Gluud, C. & Jakobsen, J. C., 4 apr. 2019, I : BMJ Evidence-Based Medicine. 24, 5, s. 185-189

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Carotid endarterectomy with primary closure versus patch angioplasty in patients with symptomatic and significant stenosis: protocol for a systematic review with meta-analyses and trial sequential analysis of randomised clinical trials

Marsman, M. S., Wetterslev, J., Jahrome, A. K., Gluud, C., Moll, F. L., Karimi, A., Keus, F. & Koning, G. G., 4 apr. 2019, I : BMJ Open. 9, 4, s. e026419

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Radix Sophorae flavescentis versus no intervention or placebo for chronic hepatitis B

Liang, N., Kong, D. Z., Ma, S. S., Lu, C. L., Yang, M., Feng, L. D., Shen, C., Diao, R. H., Cui, L. J., Lu, X. Y., Nikolova, D., Jakobsen, J. C., Gluud, C. & Liu, J. P., 3 apr. 2019, I : Cochrane Database of Systematic Reviews. 4, s. CD013089

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Dexmedetomidine for the management of delirium in critically ill patients-A protocol for a systematic review

Maagaard, M., Barbateskovic, M., Perner, A., Jakobsen, J. C. & Wetterslev, J., apr. 2019, I : Acta Anaesthesiologica Scandinavica. 63, 4, s. 549-557 9 s.

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Dexmedetomidine for the prevention of delirium in critically ill patients - A protocol for a systematic review

Maagaard, M., Barbateskovic, M., Perner, A., Jakobsen, J. C. & Wetterslev, J., apr. 2019, I : Acta Anaesthesiologica Scandinavica. 63, 4, s. 540-548 9 s.

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Methodological advantages and disadvantages of parallel and crossover randomised clinical trials on methylphenidate for attention deficit hyperactivity disorder: a systematic review and meta-analyses

Krogh, H. B., Storebø, O. J., Faltinsen, E., Todorovac, A., Ydedahl-Jensen, E., Magnusson, F. L., Holmskov, M., Gerner, T., Gluud, C. & Simonsen, E., 30 mar. 2019, I : BMJ Open. 9, 3, s. e026478

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Glucocorticosteroids for sepsis in children. A protocol for a systematic review

Korang, S. K., Gluud, C. & Jakobsen, J. C., 28 mar. 2019, I : Acta Anaesthesiologica Scandinavica. 63, 6, s. 819-826

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Error Matrix Tool to Overview the Validity of Evidence on Radix Sophorae flavescentis for Chronic Hepatitis B

Liang, N., Kong, D-Z., Ma, S-S., Lu, C-L., Yang, M., Feng, L-D., Liu, X-H., Gluud, C. & Liu, J-P., 18 mar. 2019, I : Journal of Alternative and Complementary Medicine. 25, 9, s. 957-973

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Low vs. high hemoglobin trigger for Transfusion in Vascular surgery (TV): a randomized clinical feasibility trial

Møller, A., Nielsen, H. B., Wetterslev, J., Pedersen, O. B., Hellemann, D., Winkel, P., Marcussen, K. V., Ramsing, B. G. U., Mortensen, A., Jakobsen, J. C. & Shahidi, S., 11 mar. 2019, I : Blood. 133, 25, s. 2639-2650

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Pharmacological interventions for prevention and management of delirium in intensive care patients: a systematic overview of reviews and meta-analyses

Barbateskovic, M., Krauss, S. R., Collet, M. O., Larsen, L. K., Jakobsen, J. C., Perner, A. & Wetterslev, J., 19 feb. 2019, I : BMJ Open. 9, 2, s. e024562

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Effect of Combination of Paracetamol (Acetaminophen) and Ibuprofen vs Either Alone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty: The PANSAID Randomized Clinical Trial

Thybo, K. H., Hägi-Pedersen, D., Dahl, J. B., Wetterslev, J., Nersesjan, M., Jakobsen, J. C., Pedersen, N. A., Overgaard, S., Schrøder, H. M., Schmidt, H., Bjørck, J. G., Skovmand, K., Frederiksen, R., Buus-Nielsen, M., Sørensen, C. V., Kruuse, L. S., Lindholm, P. & Mathiesen, O., 12 feb. 2019, I : JAMA - Journal of the American Medical Association. 321, 6, s. 562-571 10 s.

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Illness management and recovery: one-year follow-up of a randomized controlled trial in Danish community mental health centers: long-term effects on clinical and personal recovery

Jensen, S. B., Dalum, H. S., Korsbek, L., Hjorthøj, C., Mikkelsen, J. H., Thomsen, K., Kistrup, K., Olander, M., Lindschou, J., Mueser, K. T., Nordentoft, M. & Eplov, L. F., 11 feb. 2019, I : BMC Psychiatry. 19, 1, s. 65

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Ivabradine for coronary artery disease and/or heart failure-a protocol for a systematic review of randomised clinical trials with meta-analysis and Trial Sequential Analysis

Maagaard, M., Nielsen, E. E., Gluud, C. & Jakobsen, J. C., 1 feb. 2019, I : Systematic Reviews. 8, 1, s. 39

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