Loop diuretics in adult intensive care patients with fluid overload: A protocol for a systematic review of randomised clinical trials with meta-analysis and Trial Sequential Analysis

Wichmann, S., Barbateskovic, M., Lindschou, J., Gluud, C., Perner, A. & Bestle, M. H., 1 okt. 2020, I : Acta Anaesthesiologica Scandinavica. 64, 9, s. 1327-1334

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The Agents Intervening against Delirium in the Intensive Care Unit-Trial (AID-ICU trial):- a detailed statistical analysis plan

Andersen-Ranberg, N., Poulsen, L. M., Perner, A., Wetterslev, J., Mathiesen, O., Mortensen, C. B., Estrup, S., Ebdrup, B. H., Hästbacka, J., Citerio, G., Caballero, J., Morgan, M. P. G., Oxenbøll-Collet, M., Weber, S-O., Andreasen, A. S., Bestle, M. H., Pedersen, H. B. S., Nielsen, L. G., Uslu, B., Jensen, T. B., Thee, C., Dey, N. & Lange, T., 1 okt. 2020, I : Acta Anaesthesiologica Scandinavica. 64, 9, s. 1357-1364 8 s.

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Metformin may adversely affect orthostatic blood pressure recovery in patients with type 2 diabetes: substudy from the placebo-controlled Copenhagen Insulin and Metformin Therapy (CIMT) trial

CIMT study group, 26 sep. 2020, I : Cardiovascular Diabetology. 19, 1, s. 150

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Prognostic value of 12 novel cardiological biomarkers in stable coronary artery disease. A 10-year follow-up of the placebo group of the Copenhagen CLARICOR trial

Winkel, P., Jakobsen, J. C., Hilden, J., Jensen, G. B., Kjøller, E., Sajadieh, A., Kastrup, J., Kolmos, H. J., Iversen, K. K., Bjerre, M., Larsson, A., Ärnlöv, J. & Gluud, C., 20 aug. 2020, I : BMJ Open. 10, 8, e033720.

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Early head-up mobilisation versus standard care for patients with severe acquired brain injury: A systematic review with meta-analysis and Trial Sequential Analysis

Riberholt, C. G., Wagner, V., Lindschou, J., Gluud, C., Mehlsen, J. & Møller, K., 13 aug. 2020, I : PLoS One. 15, 8, e0237136.

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Was amorphous aluminium hydroxyphosphate sulfate adequately evaluated before authorisation in Europe?

Petersen, S. B. & Gluud, C., 6 aug. 2020, I : BMJ Evidence-Based Medicine.

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Effect of Metformin vs. Placebo in Combination with Insulin Analogues on Bone Markers P1NP and CTX in Patients with Type 2 Diabetes Mellitus

Nordklint, A. K., Almdal, T. P., Vestergaard, P., Lundby-Christensen, L., Jørgensen, N. R., Boesgaard, T. W., Breum, L., Gade-Rasmussen, B., Sneppen, S. B., Gluud, C., Hemmingsen, B., Krarup, T., Madsbad, S., Mathiesen, E. R., Perrild, H., Tarnow, L., Thorsteinsson, B., Vestergaard, H., Lund, S. S. & Eiken, P., aug. 2020, I : Calcified Tissue International. 107, 2, s. 160-169 10 s.

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Should antidepressants be used for major depressive disorder?

Jakobsen, J. C., Gluud, C. & Kirsch, I., aug. 2020, I : BMJ Evidence-Based Medicine. 25, 4, s. 130-136 7 s.

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The PANSAID Randomized Clinical Trial: A pre-planned 1-year follow-up regarding harm

Thybo, K. H., Hägi-Pedersen, D., Wetterslev, J., Overgaard, S. & Mathiesen, O., aug. 2020, I : Acta Anaesthesiologica Scandinavica. 64, 7, s. 910-912 3 s.

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Low-dose hydrocortisone in patients with COVID-19 and severe hypoxia (COVID STEROID) trial-Protocol and statistical analysis plan

Petersen, M. W., Meyhoff, T. S., Helleberg, M., Kjær, M-B. N., Granholm, A., Hjortsø, C. J. S., Jensen, T. S., Møller, M. H., Hjortrup, P. B., Wetterslev, M., Vesterlund, G. K., Russell, L., Jørgensen, V. L., Tjelle, K., Benfield, T., Ulrik, C. S., Andreasen, A. S., Mohr, T., Bestle, M. H., Poulsen, L. M., Hitz, M. F., Hildebrandt, T., Knudsen, L. S., Møller, A., Sølling, C. G., Brøchner, A. C., Rasmussen, B. S., Nielsen, H., Christensen, S., Strøm, T., Cronhjort, M., Wahlin, R. R., Jakob, S., Cioccari, L., Venkatesh, B., Hammond, N., Jha, V., Myatra, S. N., Gluud, C., Lange, T. & Perner, A., 21 jul. 2020, I : Acta Anaesthesiologica Scandinavica.

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Prediction of carotid intima-media thickness and its relation to cardiovascular events in persons with type 2 diabetes

CIMT Trial group, 18 jul. 2020, I : Journal of Diabetes and its Complications. s. 107681

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Higher versus lower oxygenation strategies in acutely ill adults. A systematic review with meta-analysis and Trial Sequential Analysis

Barbateskovic, M., Schjørring, O. L., Krauss, S. R., Meyhoff, C. S., Jakobsen, J. J., Rasmussen, B. S., Perner, A. & Wetterslev, J., 17 jul. 2020, I : Chest.

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DEX-2-TKA - DEXamethasone twice for pain treatment after Total Knee Arthroplasty. Detailed statistical analysis plan for a randomized, blinded, three-group multicentre clinical trial

Gasbjerg, K. S., Hägi-Pedersen, D., Lunn, T. H., Overgaard, S., Pedersen, N. A., Bagger, J., Lindholm, P., Brorson, S., Schrøder, H. M., Thybo, K. H., Mathiesen, O. & Jakobsen, J. C., jul. 2020, I : Acta Anaesthesiologica Scandinavica. 64, 6, s. 839-846 8 s.

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Dr. Uhre et al. Reply

Uhre, V. F., Uhre, C. F., Lønfeldt, N. N., Pretzmann, L., Vangkilde, S., Plessen, K. J., Gluud, C., Jakobsen, J. C. & Pagsberg, A. K., jul. 2020, I : Journal of the American Academy of Child and Adolescent Psychiatry. 59, 7, s. 787-791 5 s.

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Prophylactic use of acid suppressants in adult acutely ill hospitalised patients: a systematic review with meta-analysis and trial sequential analysis

Marker, S., Barbateskovic, M., Perner, A., Wetterslev, J., Jakobsen, J. C., Krag, M., Granholm, A., Anthon, C. T. & Møller, M. H., jul. 2020, I : Acta Anaesthesiologica Scandinavica. 64, 6, s. 714-728 15 s.

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Response

Meyhoff, T. S., Møller, M. H., Hjortrup, P. B., Cronhjort, M., Perner, A. & Wetterslev, J., jul. 2020, I : Chest. 158, 1, s. 428

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The handling oxygenation targets in the intensive care unit (HOT-ICU) trial: Detailed statistical analysis plan

Schjørring, O. L., Klitgaard, T. L., Perner, A., Wetterslev, J., Lange, T., Keus, F., Laake, J. H., Morgan, M., Bäcklund, M., Siegemund, M., Thormar, K. M. & Rasmussen, B. S., jul. 2020, I : Acta Anaesthesiologica Scandinavica. 64, 6, s. 847-856 10 s.

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Effects of adding adjunctive hyperbaric oxygen therapy to standard wound care for diabetic foot ulcers: a protocol for a systematic review with meta-analysis and trial sequential analysis

Vinkel, J., Holm, N. F. R., Jakobsen, J. C. & Hyldegaard, O., 29 jun. 2020, I : BMJ Open. 10, 6, s. e031708

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Maternal Sildenafil vs Placebo in Pregnant Women With Severe Early-Onset Fetal Growth Restriction: A Randomized Clinical Trial

Dutch STRIDER Trial Group, 1 jun. 2020, I : JAMA network open. 3, 6, s. e205323

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Internet-based therapy with FearFighter for anxiety disorders: a randomised clinical trial

Fenger, M., Lindschou, J., Gluud, C., Winkel, P., Jørgensen, L., Dybkjaer, J. H. & Lau, M., 13 maj 2020, I : Nordic Journal of Psychiatry. s. 1-7 7 s.

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Interventions for treatment of COVID-19: a protocol for a living systematic review with network meta-analysis including individual patient data (The LIVING Project)

Juul, S., Nielsen, N., Bentzer, P., Veroniki, A. A., Thabane, L., Linder, A., Klingenberg, S., Gluud, C. & Jakobsen, J. C., 9 maj 2020, I : Systematic Reviews. 9, 1, s. 108

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Long-term mortality in the Intermediate care after emergency abdominal surgery (InCare) trial - a post-hoc follow-up study

Hansted, A. K., Møller, M. H., Møller, A. M., Wetterslev, J., Rosenberg, J., Jorgensen, L. N., Waldau, T. & Vester-Andersen, M., 9 maj 2020, I : Acta Anaesthesiologica Scandinavica.

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Exploratory analyses of the Danish Palliative Care Trial (DanPaCT): a randomized trial of early specialized palliative care plus standard care versus standard care in advanced cancer patients

Johnsen, A. T., Petersen, M. A., Sjøgren, P., Pedersen, L., Neergaard, M. A., Damkier, A., Gluud, C., Fayers, P., Lindschou, J., Strömgren, A. S., Nielsen, J. B., Higginson, I. J. & Groenvold, M., maj 2020, I : Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer. 28, 5, s. 2145-2155 11 s.

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Protocol for outcome reporting and follow-up in the Targeted Hypothermia versus Targeted Normothermia after Out-of-Hospital Cardiac Arrest trial (TTM2)

Lilja, G., Nielsen, N., Ullén, S., Nordstrom, E. B., Dankiewicz, J., Friberg, H., Heimburg, K., Jakobsen, J. C., Levin, H., Callaway, C., Cariou, A., Eastwood, G. M., Helbok, R., Hovdenes, J., Kirkegaard, H., Leithner, C., Morgan, M. P. G., Nordberg, P., Oddo, M., Pelosi, P., Rylander, C., Saxena, M., Taccone, F. S., Siranec, M., Wise, M. P., Young, P. J. & Cronberg, T., maj 2020, I : Resuscitation. 150, s. 104-112 9 s.

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Self-determination theory interventions versus usual care in people with diabetes: a protocol for a systematic review with meta-analysis and Trial Sequential Analysis. Under review.

Mathiesen, A. S., Rothmann, M., Zoffmann, V., Jakobsen, J. C., Gluud, C., Lindschou, J., Due-Christensen, M., Rasmussen, B., H.S. Marqvordsen, E. & Thomsen, T., maj 2020, I : Prospero.

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Serum osteoprotegerin as a long-term predictor for patients with stable coronary artery disease and its association with diabetes and statin treatment: A CLARICOR trial 10-year follow-up substudy

Bjerre, M., Hilden, J., Winkel, P., Jensen, G. B., Kjøller, E., Sajadieh, A., Kastrup, J., Kolmos, H. J., Larsson, A., Ärnlöv, J., Jakobsen, J. C. & Gluud, C., maj 2020, I : Atherosclerosis. 301, s. 8-14 7 s.

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Methylphenidate for ADHD rejected from the WHO Essential Medicines List due to uncertainties in benefit-harm profile

Storebø, O. J. & Gluud, C., 24 apr. 2020, I : BMJ Evidence-Based Medicine.

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Eversion technique versus conventional endarterectomy with patch angioplasty in carotid surgery: protocol for a systematic review with meta-analyses and trial sequential analysis of randomised clinical trials

Marsman, M. S., Wetterslev, J., Vriens, P. W. H. E., Bleys, R. L. A. W., Jahrome, A. K., Moll, F. L., Keus, F. & Koning, G. G., 19 apr. 2020, I : BMJ Open. 10, 4, s. e030503

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Arterial oxygen tensions in mechanically ventilated ICU patients and mortality: a retrospective, multicentre, observational cohort study

Schjørring, O. L., Jensen, A. K. G., Nielsen, C. G., Ciubotariu, A., Perner, A., Wetterslev, J., Lange, T. & Rasmussen, B. S., apr. 2020, I : British Journal of Anaesthesia. 124, 4, s. 420-429 10 s.

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Heterogeneity of treatment effect of prophylactic pantoprazole in adult ICU patients: a post hoc analysis of the SUP-ICU trial

Granholm, A., Marker, S., Krag, M., Zampieri, F. G., Thorsen-Meyer, H-C., Kaas-Hansen, B. S., van der Horst, I. C. C., Lange, T., Wetterslev, J., Perner, A. & Møller, M. H., apr. 2020, I : Intensive Care Medicine. 46, 4, s. 717-726 10 s.

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Letter to the Editor: Glucocorticosteroids for Alcohol-Associated Hepatitis

Varganova, D. L., Pavlov, C. S., Casazza, G., Nikolova, D. & Gluud, C., apr. 2020, I : Hepatology (Baltimore, Md.). 71, 4, s. 1524

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Early specialised palliative care: interventions, symptoms, problems

Skjoedt, N., Johnsen, A. T., Sjøgren, P., Neergaard, M. A., Damkier, A., Gluud, C., Lindschou, J., Fayers, P., Higginson, I. J., Strömgren, A. S. & Groenvold, M., 27 mar. 2020, I : BMJ Supportive and Palliative Care.

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Prognosis and Reclassification by YKL-40 in Stable Coronary Artery Disease

Schroder, J., Jakobsen, J. C., Winkel, P., Hilden, J., Jensen, G. B., Sajadieh, A., Larsson, A., Ärnlöv, J., Harutyunyan, M., Johansen, J. S., Kjøller, E., Gluud, C. & Kastrup, J., 3 mar. 2020, I : Journal of the American Heart Association. 9, 5, s. e014634

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Hyperoxia and antioxidants during major non-cardiac surgery and risk of cardiovascular events: Protocol for a 2 × 2 factorial randomised clinical trial

Petersen, C., Loft, F. C., Aasvang, E. K., Vester-Andersen, M., Rasmussen, L. S., Wetterslev, J., Jorgensen, L. N., Christensen, R. & Meyhoff, C. S., mar. 2020, I : Acta Anaesthesiologica Scandinavica. 64, 3, s. 400-409 10 s.

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Health apps targeting children with overweight-a protocol for a systematic review with meta-analysis and Trial Sequential Analysis of randomised clinical trials

Rashid, R., Perego, P., Condon, L., Jakobsen, J. C., Lindschou, J., Gluud, C., Andreoni, G. & Lissau, I., 11 feb. 2020, I : Systematic Reviews. 9, 1, 28.

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Haloperidol for the treatment of delirium in critically ill patients: a systematic review with meta-analysis and Trial Sequential Analysis

Barbateskovic, M., Krauss, S. R., Collet, M. O., Andersen-Ranberg, N. C., Mathiesen, O., Jakobsen, J. C., Perner, A. & Wetterslev, J., feb. 2020, I : Acta Anaesthesiologica Scandinavica. 64, 2, s. 254-266 13 s.

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Assessment of assumptions of statistical analysis methods in randomised clinical trials: the what and how

Nørskov, A. K., Lange, T., Nielsen, E. E., Gluud, C., Winkel, P., Beyersmann, J., de Uña-Álvarez, J., Torri, V., Billot, L., Putter, H., Wetterslev, J., Thabane, L. & Jakobsen, J. C., 27 jan. 2020, I : BMJ Evidence-Based Medicine.

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Dynamic LED-light versus static LED-light for depressed inpatients: study protocol for a randomised clinical study

Volf, C., Aggestrup, A. S., Petersen, P. M., Dam-Hansen, C., Knorr, U., Petersen, E. E., Engstrøm, J., Jakobsen, J. C., Hansen, T. S., Madsen, H. Ø., Hageman, I. & Martiny, K., 26 jan. 2020, I : BMJ Open. 10, 1, s. e032233

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Lower versus higher fluid volumes during initial management of sepsis - a systematic review with meta-analysis and trial sequential analysis

Meyhoff, T. S., Møller, M. H., Hjortrup, P. B., Cronhjort, M., Perner, A. & Wetterslev, J., 23 jan. 2020, I : Chest. 20, s. 30123-9 pii: S0012-3692.

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Pregnancy Associated Plasma Protein-A as a Cardiovascular Risk Marker in Patients with Stable Coronary Heart Disease During 10 Years Follow-Up-A CLARICOR Trial Sub-Study

Nilsson, E., Kastrup, J., Sajadieh, A., Boje Jensen, G., Kjøller, E., Kolmos, H. J., Wuopio, J., Nowak, C., Larsson, A., Jakobsen, J. C., Winkel, P., Gluud, C., Iversen, K. K., Ärnlöv, J. & Carlsson, A. C., 18 jan. 2020, I : Journal of Clinical Medicine. 9, 1

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Sertraline in primary care: comments on the PANDA trial

Hengartner, M. P., Plöderl, M., Braillon, A., Jakobsen, J. C. & Gluud, C., jan. 2020, I : The Lancet. Psychiatry. 7, 1, s. 17

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Systematic Review and Meta-Analysis: Cognitive-Behavioral Therapy for Obsessive-Compulsive Disorder in Children and Adolescents

Uhre, C. F., Uhre, V. F., Lønfeldt, N. N., Pretzmann, L., Vangkilde, S., Plessen, K. J., Gluud, C., Jakobsen, J. C. & Pagsberg, A. K., jan. 2020, I : Journal of the American Academy of Child and Adolescent Psychiatry. 59, 1, s. 64-77 14 s.

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Benefits and harm of paracetamol and ibuprofen in combination for postoperative pain: preplanned subgroup analyses of the multicenter randomized PANSAID trial

Thybo, K. H., Hägi-Pedersen, D., Wetterslev, J., Dahl, J. B., Jakobsen, J. C., Pedersen, N. A., Jakobsen, K., Bülow, H. H., Ibsen, L., Overgaard, S. & Mathiesen, O., 2020, I : Acta Anaesthesiologica Scandinavica. 64, 2, s. 245-253

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Considerations on the strengths and limitations of using disease-related mortality as an outcome in clinical research

Jakobsen, J. C., Wetterslev, J. & Gluud, C., 2020, I : BMJ Evidence-Based Medicine.

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Dynamic LED light versus static LED light for depressed inpatients: results from a randomized feasibility trial

Volf, C., Aggestrup, A. S., Svendsen, S. D., Hansen, T. S., Petersen, P. M., Dam-Hansen, C., Knorr, U., Petersen, E. E., Engstrøm, J., Hageman, I., Jakobsen, J. C. & Martiny, K., 2020, I : Pilot and Feasibility Studies. 6, s. 5

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Efficacy of new-generation antidepressants assessed with the Montgomery-Asberg Depression Rating Scale, the gold standard clinician rating scale: A meta-analysis of randomised placebo-controlled trials

Hengartner, M. P., Jakobsen, J. C., Sørensen, A. & Plöderl, M., 2020, I : PLoS One. 15, 2, s. e0229381

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Long-term patient-important outcomes after septic shock: a protocol for 1-year follow-up of the CLASSIC-trial

Kjaer, M-B. N., Meyhoff, T. S., Madsen, M. B., Hjortrup, P. B., Møller, M. H., Egerod, I., Wetterslev, J., Lange, T., Cronhjort, M., Laake, J. H., Jakob, S. M., Nalos, M., Pettilä, V., van der Horst, I. C. C., Ostermann, M., Mouncey, P., Cecconi, M., Ferrer, R., L N G Malbrain, M., Ahlstedt, C., Hoffmann, S., Bestle, M. H., Gyldensted, L., Nebrich, L., Russell, L., Vang, M., Sølling, C., Brøchner, A. C., Rasmussen, B. S. & Perner, A., 2020, I : Acta Anaesthesiologica Scandinavica. 64, s. 410–416

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Plexus anesthesia versus general anesthesia in patients for carotid endarterectomy with patch angioplasty: Protocol for a systematic review with meta-analyses and Trial Sequential Analysis of randomized clinical trials

Marsman, M. S., Wetterslev, J., Keus, F., van Aalst, D., van Rooij, F. G., Heyligers, J. M. M., Moll, F. L., Jahrome, A. K., Vriens, P. W. H. E. & Koning, G. G., 2020, I : International Journal of Surgery Protocols. 19, s. 1-7 7 s.

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Cerebral near-infrared spectroscopy monitoring versus treatment as usual for extremely preterm infants: a protocol for the SafeBoosC randomised clinical phase III trial

Hansen, M. L., Pellicer, A., Gluud, C., Dempsey, E., Mintzer, J., Hyttel-Sørensen, S., Heuchan, A. M., Hagmann, C., Ergenekon, E., Dimitriou, G., Pichler, G., Naulaers, G., Cheng, G., Guimarães, H., Tkaczyk, J., Kreutzer, K. B., Fumagalli, M., Claris, O., Lemmers, P., Fredly, S., Szczapa, T., Austin, T., Jakobsen, J. C. & Greisen, G., 30 dec. 2019, I : Trials. 20, 1, s. 811

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