Research
Print page Print page
Switch language
Bispebjerg Hospital - a part of Copenhagen University Hospital
Published

The use of combined heart rate response and accelerometry to assess the level and predictors of physical activity in tuberculosis patients in Tanzania

Research output: Contribution to journalJournal articleResearchpeer-review

  1. Seroincidence of non-typhoid Salmonella infections: convenience vs. random community-based sampling

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Seroepidemiology of pertussis in a cross-sectional study of an adult general population in Denmark

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Trimethoprim use in early pregnancy and the risk of miscarriage: a register-based nationwide cohort study

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Thermostability of IFN-γ and IP-10 release assays for latent infection with Mycobacterium tuberculosis: A TBnet study

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Increased level of acute phase reactants in patients infected with modern Mycobacterium tuberculosis genotypes in Mwanza, Tanzania

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. The association between conventional risk factors and diabetes is weak among urban Tanzanians

    Research output: Contribution to journalJournal articleResearchpeer-review

  • M. Faurholt-Jepsen
  • D. Faurholt-Jepsen
  • N Range
  • G Praygod
  • K Jeremiah
  • M. G. Aabye
  • J Changalucha
  • H Krarup
  • D. L. Christensen
  • A. B. Andersen
  • Soren Brage
  • H Friis
View graph of relations

We assessed the role of tuberculosis (TB) disease and HIV infection on the level of physical activity. A combined heart rate and movement sensor was used to assess habitual physical activity in TB patients and non-TB controls. The association between sputum-negative TB, sputum-positive TB, HIV and physical activity estimates were assessed in multivariable linear regression models adjusted for age, sex, haemoglobin and alpha-1-Acid glycoprotein (AGP). Sputum-positive [eB 0·43, 95% confidence interval (CI) 0·29-0·64] and sputum-negative (eB 0·67, 95% CI 0·47-0·94) TB as well as HIV infection (eB 0·59, 95% CI 0·46-0·75) were associated with reduced activity compared to controls. Anaemia accounted for a substantial part of the effects of HIV, while elevated AGP primarily mediated the TB effect. The level of physical activity is highly influenced by TB and HIV, and mainly mediated through anaemia of infection and associated with elevated acute phase response.

Original languageEnglish
JournalEpidemiology and Infection
Volume142
Issue number6
Pages (from-to)1334-1342
Number of pages9
ISSN0950-2688
DOIs
Publication statusPublished - 2014

    Research areas

  • Epidemiology, HIV/AIDS, infectious disease epidemiology, lung infection, tuberculosis (TB)

ID: 51559318