Print page Print page
Switch language
Bispebjerg Hospital - a part of Copenhagen University Hospital

Systematic Medication Review in General Practice by an Interdisciplinary Team: A thorough but Laborious Method to Address Polypharmacy among Elderly Patients

Research output: Contribution to journalJournal articlepeer-review


  1. Short-term mortality following tramadol poisonings in Denmark

    Research output: Contribution to journalJournal articlepeer-review

  2. Mirtazapine exposure in pregnancy and fetal safety: A nationwide cohort study

    Research output: Contribution to journalJournal articlepeer-review

  3. Exposure to Tramadol During Early Pregnancy and Risk of Spontaneous Abortion or Major Congenital Malformations

    Research output: Contribution to journalJournal articlepeer-review

  4. The Blind Spot of Pharmacology: A Scoping Review of Drug Metabolism in Prematurely Born Children

    Research output: Contribution to journalReviewpeer-review

View graph of relations

Polypharmacy increases the risk of hospitalization but may be reduced by medication review. The study objective is to describe and evaluate a method for conducting medication review in general practice by an interdisciplinary medication team of pharmacists and physicians-in this case conducted by a team from the Department of Clinical Pharmacology-based on information concerning medication, diagnosis, relevant laboratory data and medical history supplied by the general practitioner. We discussed the medication review with the patients' general practitioners and received feedback from them regarding acceptance rates of the recommended changes. Ninety-four patients with a total of 1471 prescriptions were included. A medication change was recommended for nearly half of the prescriptions (48%); at least one change of medication was recommended for all patients. The acceptance rate for recommended medication changes was 55%, corresponding to a mean of 4.2 accepted recommendations per patient. For 18% of all 1471 prescriptions, the general practitioner agreed either to discontinue (stop the medication completely) or reduce the dose of the medication. This method is thorough, but since it requires several healthcare professionals, it is rather time-consuming. There is a need to support medication review in general practice, but although this method may be too time consuming in most cases, it may nevertheless prove to be a useful tool managing the most complicated patients.

Original languageEnglish
JournalPharmacy (Basel, Switzerland)
Issue number2
Publication statusPublished - 31 Mar 2020

    Research areas

  • medication errors, general practice, general practitioners, family practice, pharmacists, aged, aged 80 and over, polypharmacy, deprescriptions, healthcare professional, medication review, medicine review

ID: 59855760