Research
Print page Print page
Switch language
Bispebjerg Hospital - a part of Copenhagen University Hospital
Published

Molecular Typing of Treponema pallidum in Denmark: A Nationwide Study of Syphilis

Research output: Contribution to journalJournal articleResearchpeer-review

DOI

  1. Management of Ocular Manifestations of Atopic Dermatitis: A Consensus Meeting Using a Modified Delphi Process

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Clinical Management of Atopic Dermatitis in Adults: Mapping of Expert Opinion in 4 Nordic Countries using a Modified Delphi Process

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Patient-reported Outcomes During Treatment in Patients with Moderate-to-severe Psoriasis: A Danish Nationwide Study

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Prevalence, type distribution, and risk factors for oral HPV in Danish renal transplant recipients

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Risk of genital warts in renal transplant recipients-A registry-based, prospective cohort study

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Seksuelt overførbare infektioner

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

  4. Seksuelt overførbare infektioner

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

  5. Seksuelt overførbare infektioner - fra praksis til hospital

    Research output: Contribution to journalJournal articleCommunication

  • Kirsten Salado-Rasmussen
  • Susan Cowan
  • Jan Gerstoft
  • Helle Kiellberg Larsen
  • Steen Hoffmann
  • Troels Bygum Knudsen
  • Terese Lea Katzenstein
  • Jørgen Skov Jensen
View graph of relations

The aim of this nationwide study is to determine the strain type diversity among patients diagnosed with syphilis by PCR during a 4-year period in Denmark. Epidemiological data, including HIV status, for all patients were obtained from the Danish national syphilis registration system. Molecular strain typing was based on characterization of 3 variable treponemal genes, arp, tpr and tp0548. A total of 278 specimens from 269 patients were included. Among the fully typeable specimens (n = 197), 22 strain types were identified, with 1 type, 14 d/g, accounting for 54%. The majority (93%) of the patients reported acquiring syphilis in Denmark. Among patients with concurrent HIV, 9 full strain types were identified and no difference in strain type was found by HIV status (p = 0.197). In conclusion, the majority of patients were infected in Denmark and the HIV-infected syphilis patients were diagnosed with a wide spectrum of different strain types of Treponema pallidum.

Original languageEnglish
JournalActa Dermatovenereologica
Volume96
Pages (from-to)202-206
ISSN0001-5555
DOIs
Publication statusPublished - 2016

ID: 45731506