Research
Print page Print page
Switch language
Bispebjerg Hospital - a part of Copenhagen University Hospital
Published

Body mass index and height in relation to type 2 diabetes by levels of intelligence and education in a large cohort of Danish men

Research output: Contribution to journalJournal articleResearchpeer-review

  1. Body mass index in young adulthood and risk of subsequent dementia at different levels of intelligence and education in Danish men

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Body mass index and risk of infections: a Mendelian randomization study of 101,447 individuals

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Early life body size in relation to risk of renal cell carcinoma in adulthood: a Danish observational cohort study

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Blood-brain barrier transcytosis genes, risk of dementia and stroke: a prospective cohort study of 74,754 individuals

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Treatment-resistant depression and risk of all-cause mortality and suicidality in Danish patients with major depression

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Associations between body mass index trajectories in childhood and cardiovascular risk factors in adulthood

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Early life body size, growth and risks of systemic lupus erythematosus - A large Danish observational cohort study

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Familial risk and heritability of depression by age at first diagnosis in Danish twins

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations

Socioeconomic status (SES) is inversely associated with risks of type 2 diabetes (T2D). We investigated if young men's cognitive function, measured by intelligence test scores and educational level, as determinants of SES modified associations between body mass index (BMI) and height with the risk of T2D. 369 989 young men from the Danish Conscription Database born between 1939 and 1959 with information on measured height, weight, intelligence test scores, and education were linked to the Danish National Patient Register. During follow-up from 1977 through 2015, T2D was recorded in 32 188 men. Hazard ratios (HR) and 95% confidence intervals (95% CI) were estimated by Cox regressions. BMIs below-average (z-scores ≤ 0) were not related to risks of T2D. For BMIs above-average (z-scores > 0), positive associations between BMI and T2D were slightly stronger among men with higher intelligence test scores or longer educations than among men with lower levels of these factors (pinteraction-values < 0.004). Irrespective of BMI, incidence rates of T2D were higher among men with low levels of intelligence test score and education. Height was inversely associated with T2D (per z-score, HR = 0.96 (95% CI 0.95-0.97) and the association did not vary by intelligence test scores or education (all pinteraction-values > 0.59). While below-average BMI was not associated with T2D risk, above-average BMIs were and these association were stronger among men with high cognitive function. Nevertheless, T2D risk was higher at lower levels of cognitive function throughout the range of BMI. Height was inversely associated with T2D and it was not modified by cognitive function.

Original languageEnglish
JournalEuropean Journal of Epidemiology
Volume35
Issue number12
Pages (from-to)1167-1175
Number of pages9
ISSN0393-2990
DOIs
Publication statusPublished - Dec 2020

    Research areas

  • Adolescent, Adult, Aged, Body Height, Body Mass Index, Cognition, Cohort Studies, Denmark/epidemiology, Diabetes Mellitus, Type 2/epidemiology, Educational Status, Humans, Incidence, Intelligence, Intelligence Tests/statistics & numerical data, Male, Middle Aged, Social Class, Young Adult

ID: 59830556