Harvard
Csengeri, D, Sprünker, N-A, Di Castelnuovo, A, Niiranen, T
, Vishram-Nielsen, JK, Costanzo, S, Söderberg, S, Jensen, SM, Vartiainen, E, Donati, MB, Magnussen, C, Camen, S, Gianfagna, F, Løchen, M-L, Kee, F, Kontto, J, Mathiesen, EB, Koenig, W, Stefan, B, de Gaetano, G
, Jørgensen, T, Kuulasmaa, K, Zeller, T, Salomaa, V, Iacoviello, L & Schnabel, RB 2021, '
Alcohol consumption, cardiac biomarkers, and risk of atrial fibrillation and adverse outcomes',
European Heart Journal, vol. 42, no. 12, pp. 1170-1177.
https://doi.org/10.1093/eurheartj/ehaa953APA
Csengeri, D., Sprünker, N-A., Di Castelnuovo, A., Niiranen, T.
, Vishram-Nielsen, J. K., Costanzo, S., Söderberg, S., Jensen, S. M., Vartiainen, E., Donati, M. B., Magnussen, C., Camen, S., Gianfagna, F., Løchen, M-L., Kee, F., Kontto, J., Mathiesen, E. B., Koenig, W., Stefan, B., ... Schnabel, R. B. (2021).
Alcohol consumption, cardiac biomarkers, and risk of atrial fibrillation and adverse outcomes.
European Heart Journal,
42(12), 1170-1177.
https://doi.org/10.1093/eurheartj/ehaa953CBE
Csengeri D, Sprünker N-A, Di Castelnuovo A, Niiranen T
, Vishram-Nielsen JK, Costanzo S, Söderberg S, Jensen SM, Vartiainen E, Donati MB, Magnussen C, Camen S, Gianfagna F, Løchen M-L, Kee F, Kontto J, Mathiesen EB, Koenig W, Stefan B, de Gaetano G
, Jørgensen T, Kuulasmaa K, Zeller T, Salomaa V, Iacoviello L, Schnabel RB. 2021.
Alcohol consumption, cardiac biomarkers, and risk of atrial fibrillation and adverse outcomes.
European Heart Journal. 42(12):1170-1177.
https://doi.org/10.1093/eurheartj/ehaa953MLA
Vancouver
Author
Csengeri, Dora ; Sprünker, Ngoc-Anh ; Di Castelnuovo, Augusto ; Niiranen, Teemu
; Vishram-Nielsen, Julie Kk ; Costanzo, Simona ; Söderberg, Stefan ; Jensen, Steen M ; Vartiainen, Erkki ; Donati, Maria Benedetta ; Magnussen, Christina ; Camen, Stephan ; Gianfagna, Francesco ; Løchen, Maja-Lisa ; Kee, Frank ; Kontto, Jukka ; Mathiesen, Ellisiv B ; Koenig, Wolfgang ; Stefan, Blankenberg ; de Gaetano, Giovanni
; Jørgensen, Torben ; Kuulasmaa, Kari ; Zeller, Tanja ; Salomaa, Veikko ; Iacoviello, Licia ; Schnabel, Renate B. /
Alcohol consumption, cardiac biomarkers, and risk of atrial fibrillation and adverse outcomes. In:
European Heart Journal. 2021 ; Vol. 42, No. 12. pp. 1170-1177.
Bibtex
@article{887261501d5e4b19941cfc9149912156,
title = "Alcohol consumption, cardiac biomarkers, and risk of atrial fibrillation and adverse outcomes",
abstract = "AIMS : There is inconsistent evidence on the relation of alcohol intake with incident atrial fibrillation (AF), in particular at lower doses. We assessed the association between alcohol consumption, biomarkers, and incident AF across the spectrum of alcohol intake in European cohorts.METHODS AND RESULTS : In a community-based pooled cohort, we followed 107 845 individuals for the association between alcohol consumption, including types of alcohol and drinking patterns, and incident AF. We collected information on classical cardiovascular risk factors and incident heart failure (HF) and measured the biomarkers N-terminal pro-B-type natriuretic peptide and high-sensitivity troponin I. The median age of individuals was 47.8 years, 48.3% were men. The median alcohol consumption was 3 g/day. N = 5854 individuals developed AF (median follow-up time: 13.9 years). In a sex- and cohort-stratified Cox regression analysis alcohol consumption was non-linearly and positively associated with incident AF. The hazard ratio for one drink (12 g) per day was 1.16, 95% CI 1.11-1.22, P < 0.001. Associations were similar across types of alcohol. In contrast, alcohol consumption at lower doses was associated with reduced risk of incident HF. The association between alcohol consumption and incident AF was neither fully explained by cardiac biomarker concentrations nor by the occurrence of HF.CONCLUSIONS : In contrast to other cardiovascular diseases such as HF, even modest habitual alcohol intake of 1.2 drinks/day was associated with an increased risk of AF, which needs to be considered in AF prevention.",
keywords = "Alcohol consumption, Atrial fibrillation, Biomarkers, Epidemiology",
author = "Dora Csengeri and Ngoc-Anh Spr{\"u}nker and {Di Castelnuovo}, Augusto and Teemu Niiranen and Vishram-Nielsen, {Julie Kk} and Simona Costanzo and Stefan S{\"o}derberg and Jensen, {Steen M} and Erkki Vartiainen and Donati, {Maria Benedetta} and Christina Magnussen and Stephan Camen and Francesco Gianfagna and Maja-Lisa L{\o}chen and Frank Kee and Jukka Kontto and Mathiesen, {Ellisiv B} and Wolfgang Koenig and Blankenberg Stefan and {de Gaetano}, Giovanni and Torben J{\o}rgensen and Kari Kuulasmaa and Tanja Zeller and Veikko Salomaa and Licia Iacoviello and Schnabel, {Renate B}",
note = "{\textcopyright} The Author(s) 2021. Published by Oxford University Press on behalf of the European Society of Cardiology.",
year = "2021",
month = mar,
day = "21",
doi = "10.1093/eurheartj/ehaa953",
language = "English",
volume = "42",
pages = "1170--1177",
journal = "European Heart Journal",
issn = "0195-668X",
publisher = "Oxford University Press",
number = "12",
}
RIS
TY - JOUR
T1 - Alcohol consumption, cardiac biomarkers, and risk of atrial fibrillation and adverse outcomes
AU - Csengeri, Dora
AU - Sprünker, Ngoc-Anh
AU - Di Castelnuovo, Augusto
AU - Niiranen, Teemu
AU - Vishram-Nielsen, Julie Kk
AU - Costanzo, Simona
AU - Söderberg, Stefan
AU - Jensen, Steen M
AU - Vartiainen, Erkki
AU - Donati, Maria Benedetta
AU - Magnussen, Christina
AU - Camen, Stephan
AU - Gianfagna, Francesco
AU - Løchen, Maja-Lisa
AU - Kee, Frank
AU - Kontto, Jukka
AU - Mathiesen, Ellisiv B
AU - Koenig, Wolfgang
AU - Stefan, Blankenberg
AU - de Gaetano, Giovanni
AU - Jørgensen, Torben
AU - Kuulasmaa, Kari
AU - Zeller, Tanja
AU - Salomaa, Veikko
AU - Iacoviello, Licia
AU - Schnabel, Renate B
N1 - © The Author(s) 2021. Published by Oxford University Press on behalf of the European Society of Cardiology.
PY - 2021/3/21
Y1 - 2021/3/21
N2 - AIMS : There is inconsistent evidence on the relation of alcohol intake with incident atrial fibrillation (AF), in particular at lower doses. We assessed the association between alcohol consumption, biomarkers, and incident AF across the spectrum of alcohol intake in European cohorts.METHODS AND RESULTS : In a community-based pooled cohort, we followed 107 845 individuals for the association between alcohol consumption, including types of alcohol and drinking patterns, and incident AF. We collected information on classical cardiovascular risk factors and incident heart failure (HF) and measured the biomarkers N-terminal pro-B-type natriuretic peptide and high-sensitivity troponin I. The median age of individuals was 47.8 years, 48.3% were men. The median alcohol consumption was 3 g/day. N = 5854 individuals developed AF (median follow-up time: 13.9 years). In a sex- and cohort-stratified Cox regression analysis alcohol consumption was non-linearly and positively associated with incident AF. The hazard ratio for one drink (12 g) per day was 1.16, 95% CI 1.11-1.22, P < 0.001. Associations were similar across types of alcohol. In contrast, alcohol consumption at lower doses was associated with reduced risk of incident HF. The association between alcohol consumption and incident AF was neither fully explained by cardiac biomarker concentrations nor by the occurrence of HF.CONCLUSIONS : In contrast to other cardiovascular diseases such as HF, even modest habitual alcohol intake of 1.2 drinks/day was associated with an increased risk of AF, which needs to be considered in AF prevention.
AB - AIMS : There is inconsistent evidence on the relation of alcohol intake with incident atrial fibrillation (AF), in particular at lower doses. We assessed the association between alcohol consumption, biomarkers, and incident AF across the spectrum of alcohol intake in European cohorts.METHODS AND RESULTS : In a community-based pooled cohort, we followed 107 845 individuals for the association between alcohol consumption, including types of alcohol and drinking patterns, and incident AF. We collected information on classical cardiovascular risk factors and incident heart failure (HF) and measured the biomarkers N-terminal pro-B-type natriuretic peptide and high-sensitivity troponin I. The median age of individuals was 47.8 years, 48.3% were men. The median alcohol consumption was 3 g/day. N = 5854 individuals developed AF (median follow-up time: 13.9 years). In a sex- and cohort-stratified Cox regression analysis alcohol consumption was non-linearly and positively associated with incident AF. The hazard ratio for one drink (12 g) per day was 1.16, 95% CI 1.11-1.22, P < 0.001. Associations were similar across types of alcohol. In contrast, alcohol consumption at lower doses was associated with reduced risk of incident HF. The association between alcohol consumption and incident AF was neither fully explained by cardiac biomarker concentrations nor by the occurrence of HF.CONCLUSIONS : In contrast to other cardiovascular diseases such as HF, even modest habitual alcohol intake of 1.2 drinks/day was associated with an increased risk of AF, which needs to be considered in AF prevention.
KW - Alcohol consumption
KW - Atrial fibrillation
KW - Biomarkers
KW - Epidemiology
UR - http://www.scopus.com/inward/record.url?scp=85103061402&partnerID=8YFLogxK
U2 - 10.1093/eurheartj/ehaa953
DO - 10.1093/eurheartj/ehaa953
M3 - Journal article
C2 - 33438022
VL - 42
SP - 1170
EP - 1177
JO - European Heart Journal
JF - European Heart Journal
SN - 0195-668X
IS - 12
ER -
