Forskning
Udskriv Udskriv
Switch language
Bispebjerg Hospital - en del af Københavns Universitetshospital
Udgivet

Use of register and survey-based measures of anxiety in a population based Danish cohort

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

  1. Mirtazapine exposure in pregnancy and fetal safety: A nationwide cohort study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Time course of symptoms in posttraumatic stress disorder with delayed expression: a systematic review

    Publikation: Bidrag til tidsskriftReviewForskningpeer review

  3. Number of Traumatic brain injuries and temporal associations with depression: A register-based cohort study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Severe mental illness is associated with increased mortality and severe course of COVID-19

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  5. Familial risk and heritability of depression by age at first diagnosis in Danish twins

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Depression in adulthood and risk of dementia later in life: A Danish register-based cohort study of 595,828 men

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Diabetes, antidiabetic medications and risk of depression - A population-based cohort and nested case-control study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Socioeconomic Position and Late-Onset Dementia: A Nationwide Register-Based Study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

OBJECTIVE: We explored the comparability of anxiety measures from register- and survey-based data including analyses of prevalence and associations with selected psychiatric and somatic diseases.

METHODS: We measured anxiety using Danish registers (hospital diagnosis and anxiolytic drug prescriptions), self-reports, symptom checklist (SCL) scores, and a clinical interview in 7493 adults with mean age 52 (SD 13.3) years who participated in a health survey between 2012 and 2015. We estimated the prevalence of anxiety, agreement between different measures and performed quantitative bias analysis.

RESULTS: The lifetime prevalence of hospital diagnosed anxiety, anxiolytic drug prescriptions, and self-reported anxiety were 4.4%, 6.2%, and 5.1%, respectively, after adjusting for selective participation. The agreement between the different anxiety measures was low. Thus, 25% with an anxiety diagnosis and 20% with anxiolytic drug prescriptions also had a high SCL score. Anxiolytic drugs were the only measure significantly associated with higher odds of heart disease. Hospital diagnosis and self-reported anxiety were associated with depression with odds ratio (OR) above 15, whereas anxiolytic drug prescriptions were less strongly associated (OR = 2.2(95% confidence interval: 1.26-3.91)). The risk estimates attenuated considerably when correcting for measurement error, whereas the ORs became slightly higher when the selective participation in the survey was accounted for.

CONCLUSION: Anxiety diagnosed in hospitals and self-reported anxiety showed low level of agreement but provide comparable results regarding frequency measures and associations with disease outcomes.

OriginalsprogEngelsk
TidsskriftActa Psychiatrica Scandinavica
Vol/bind144
Udgave nummer5
Sider (fra-til)501-509
Antal sider9
ISSN0001-690X
DOI
StatusUdgivet - nov. 2021

ID: 66432193