Forskning
Udskriv Udskriv
Switch language
Bispebjerg Hospital - en del af Københavns Universitetshospital
Udgivet

Tunneled Peritoneal Catheter for Refractory Ascites in Cirrhosis: A Randomized Case-Series

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

  1. Echocardiographic abnormalities and predictors of mortality in hospitalized COVID-19 patients: the ECHOVID-19 study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Dehydration as referral diagnosis to a medical admittance department

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Diagnosis and Treatment of Genetic HFE-Hemochromatosis: The Danish Aspect

    Publikation: Bidrag til tidsskriftReviewForskningpeer review

  4. Sepsis-related Organ Failure Assessment Score is a strong predictor of survival in acute-on-chronic liver failure

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  • Nina Kimer
  • Agnete Nordheim Riedel
  • Lise Hobolth
  • Christian Mortensen
  • Lone Galmstrup Madsen
  • Mette Lehmann Andersen
  • Frank Vinholdt Schiødt
  • Søren Møller
  • Lise Lotte Gluud
Vis graf over relationer

BACKGROUND AND OBJECTIVES: Refractory ascites markedly worsens prognosis in cirrhosis. Large volume paracentesis (LVP) is standard treatment, but complications are common. In a randomized controlled case-series, we assessed a permanent tunneled peritoneal catheter versus LVP in patients with cirrhosis and ascites.

MATERIALS AND METHODS: Random allocation was computer-generated, and concealment used opaque envelopes. Patients were included from January 2017 to December 2018. Inclusion criteria were cirrhosis and recurrent ascites and expected survival of more than 3 months.

RESULTS: Thirteen patients were enrolled (PleurX =6 versus LVP = 7). Seven were female, ranging in age from 51 to 80 years. No procedure-related complications occurred. Two patients died due to variceal bleeding (PleurX-group) and sepsis (LVP-group). One patient was withdrawn due to hyponatremia (PleurX-group). Two patients were withdrawn due to bacterial peritonitis and infection of unknown origin (control-group). In the PleurX-group, all patients colonized the catheter, two developed bacterial peritonitis. The most common bacterial colonization was Staph. Epidermidis (n = 4).

CONCLUSIONS: In selected patients, the PleurX catheter mobilizes ascites and may be an alternative to LVP. The risk of infection should be considered in each case. The impact of colonization and risk of infections needs further investigation. The present trial does not allow for statistical conclusions.

OriginalsprogEngelsk
TidsskriftMedicina (Kaunas, Lithuania)
Vol/bind56
Udgave nummer11
ISSN1010-660X
DOI
StatusUdgivet - 27 okt. 2020

ID: 61235593