Forskning
Udskriv Udskriv
Switch language
Bispebjerg Hospital - en del af Københavns Universitetshospital
Udgivet

Long-Term Exposure to Air Pollution, Road Traffic Noise, and Heart Failure Incidence: The Danish Nurse Cohort

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

  1. Trends in Use of Cardioprotective Medication in Peripheral Artery Disease: A Nationwide Study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Time Trends in Simple Congenital Heart Disease Over 39 Years: A Danish Nationwide Study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Outcomes in Antiplatelet-Associated Intracerebral Hemorrhage in the TICH-2 Randomized Controlled Trial

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Long-term exposure to road traffic noise and all-cause and cause-specific mortality: a Danish Nurse Cohort study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Long-term exposure to air pollution and liver cancer incidence in six European cohorts

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Long-term air pollution and road traffic noise exposure and COPD: the Danish Nurse Cohort

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  • Youn-Hee Lim
  • Jeanette T Jørgensen
  • Rina So
  • Tom Cole-Hunter
  • Amar J Mehta
  • Heresh Amini
  • Elvira V Bräuner
  • Rudi G J Westendorp
  • Shuo Liu
  • Laust H Mortensen
  • Barbara Hoffmann
  • Steffen Loft
  • Matthias Ketzel
  • Ole Hertel
  • Jørgen Brandt
  • Steen Solvang Jensen
  • Claus Backalarz
  • Mette K Simonsen
  • Nebojsa Tasic
  • Matija Maric
  • Zorana J Andersen
Vis graf over relationer

Background We examined the association of long-term exposure to air pollution and road traffic noise with incident heart failure (HF). Methods And Results Using data on female nurses from the Danish Nurse Cohort (aged >44 years), we investigated associations between 3-year mean exposures to air pollution and road traffic noise and incident HF using Cox regression models, adjusting for relevant confounders. Incidence of HF was defined as the first hospital contact (inpatient, outpatient, or emergency) between cohort baseline (1993 or 1999) and December 31, 2014, based on the Danish National Patient Register. Annual mean levels of particulate matter with a diameter <2.5 µm since 1990 and NO2 and road traffic noise since 1970 were estimated at participants' residences. Of the 22 189 nurses, 484 developed HF. We detected associations with all 3 pollutants, with hazard ratios (HRs) of 1.17 (95% CI, 1.01-1.36), 1.10 (95% CI, 0.99-1.22), and 1.12 (95% CI, 0.99-1.26) per increase of 5.1 µg/m3 in particulate matter with a diameter <2.5 µm, 8.6 µg/m3 in NO2, and 9.3 dB in road traffic noise, respectively. We observed an enhanced risk of HF incidence for those exposed to high levels of the 3 pollutants; however, the effect modification of coexposure was not statistically significant. Former smokers and nurses with hypertension showed the strongest associations with particulate matter with a diameter <2.5 µm (Peffect modification<0.05). Conclusions We found that long-term exposures to air pollution and road traffic noise were independently associated with HF.

OriginalsprogEngelsk
Artikelnummere021436
TidsskriftJournal of the American Heart Association
Vol/bind10
Udgave nummer20
Sider (fra-til)e021436
ISSN2047-9980
DOI
StatusUdgivet - 19 okt. 2021

ID: 68559571