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Bispebjerg Hospital - en del af Københavns Universitetshospital
Udgivet

Is the SPINK1 variant p.N34S overrepresented in patients with acute pancreatitis?

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Vis graf over relationer
Serine Protease Inhibitor Kazal type 1 (SPINK1) protects against premature intracellular activation of trypsinogen and development of acute pancreatitis. Our aim was to determine the prevalence of SPINK1 mutations (a) in unselected patients with first-time acute pancreatitis and (b) in the Danish background population (c) in a meta-analysis to combine the results with findings in similar investigations worldwide and (d) to evaluate whether patients with SPINK1 mutations had a more severe clinical course.
OriginalsprogEngelsk
TidsskriftEuropean Journal of Gastroenterology and Hepatology
Vol/bind24
Udgave nummer3
Sider (fra-til)309-15
Antal sider7
ISSN0954-691X
DOI
StatusUdgivet - 2012

ID: 36820247