Forskning
Udskriv Udskriv
Switch language
Bispebjerg Hospital - en del af Københavns Universitetshospital
Udgivet

Associations between adult height and type 2 diabetes mellitus: a systematic review and meta-analysis of observational studies

Publikation: Bidrag til tidsskriftReviewForskningpeer review

Dokumenter

DOI

  1. Too sick to work, too healthy to qualify: a cross-country analysis of the effect of changes to disability benefits

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Applied mediation analyses: a review and tutorial

    Publikation: Bidrag til tidsskriftReviewForskningpeer review

  3. Intelligence in early adulthood and mortality from natural and unnatural causes in middle-aged Danish men

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Instrumental variable analysis using offspring BMI in childhood as an indicator of parental BMI in relation to mortality

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Airway hyperresponsiveness to inhaled mannitol identifies a cluster of non-eosinophilic asthma patients with high symptom burden

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Bariatric surgery and risk of new-onset inflammatory bowel disease: A nationwide cohort study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Fractures and Osteoporosis in Patients With Diabetes With Charcot Foot

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

BACKGROUND: Although short adult height is generally associated with increased risks of type 2 diabetes mellitus (T2DM), there are large inconsistencies across studies. The aims of this study were to describe and quantify currently available evidence on the association between adult height and T2DM, to examine whether the reported associations differ by sex, and to examine the shapes of the height and T2DM associations.

METHODS: Relevant literature was identified using PubMed (1966-May 2018), EMBASE (1947-May 2018) and Google Scholar (May 2018). We identified cross-sectional and cohort studies with original publications on human subjects, which were included in a random-effects meta-analysis.

RESULTS: From 15 971 identified sources, 25 studies met the inclusion criteria for the systematic review (N=401 562 individuals). From these 25 studies, 16 (9 cross-sectional studies and 7 cohort studies) were included in the meta-analysis (n=261 496 individuals). The overall random-effects meta-analysis indicated an inverse association between adult height and T2DM (effect estimate=0.88, 95% CI 0.81 to 0.95). No sex differences in the associations between adult height and T2DM were found (effect estimate for men: 0.86, 95% CI 0.75 to 0.99; effect estimate for women: 0.90; 95% CI 0.80 to 1.01; p value for sex interaction=0.80). Due to lack of data, results on the shape of the association between height and T2DM were inconclusive.

CONCLUSIONS: Shorter height is associated with an increased risk of T2DM and the association does not significantly differ by sex. The currently available data are insufficient to support conclusions regarding the shape of the association between height and T2DM.

TRIAL REGISTRATION NUMBER: CRD42017062446.

OriginalsprogEngelsk
TidsskriftJournal of Epidemiology and Community Health
Vol/bind73
Udgave nummer7
Sider (fra-til)681-688
Antal sider8
ISSN0143-005X
DOI
StatusUdgivet - 2019

Bibliografisk note

© Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. Published by BMJ.

Mest downloadede publikationer

Ingen data tilgængelig

ID: 56978749